Doctors Lounge - Endocrinology AnswersBack to Endocrinology Answers List
If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge (www.doctorslounge.com) does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.
DISCLAIMER: The information provided on www.doctorslounge.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.
Date of last update: 10/17/2017.
Forum Name: Diabetes
Question: insulin rsistance and very lean
|veka82 - Wed Apr 29, 2009 12:35 pm||
I'm a 26 year old female and i have receantly been diagnosed with Insulin Resistance. I went to doctor because my periods were mildly irregular and i was suffering from hirtuism.i also feel tired all the time. My fasting blood glucose levels and fasting insulin levels are in normal range, but my OGTT showed Insulin Resistance. All my other labs were normal. ( those include liver panel, minerlas, lipid profile, IgG, IgA, IgM, CRP, CEA, AFP, CA15, CA125, CA19, FSH, LH, E2, Progesteron, PRL, Testosteron, andostendion, HGH, ACTH, cortisol, 17-KS, 17-OHS). Only DHEA is elevated (17nmol/L).
I am normal weight, more like somewhat skinny. My BMI is 19.5. So what makes no sence to me is: Insulin Resistance is always linked to overweight people....
I was perscribed Metformin 500mg 2x a day. I am very concerned that the Metformin is going to make me loose even more weight. Is that a possibility?
I have not started taking the medication because of this concern yet.
thank you for answering my questions nad please excuse a ny possibe spelling errors as my english is not perfect
|Dr.M.jagesh kamath - Mon Sep 06, 2010 12:03 pm||
Hello,Insulin resistance has been found in PCOS both in the obese and lean.There is also compelling evidence that metformin increased insulin sensitivity,obviously in the obese but even in the lean as well.Thus metformin has been considered as an integral part of therapy even in the lean PCOS patients.The drug also reduces clinical manifestations of hyperandrogenism in these patients.
|| Check a doctor's response to similar questions|
Are you a Doctor, Pharmacist, PA or a Nurse?
Join the Doctors Lounge online medical community
Editorial activities: Publish, peer review, edit online articles.
Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.