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Submitted by Dr. Hesham Al-Inany, M.D. Lecturer, Gynaecology & Obstetrics dept. Kasr El-Aini hospital, Cairo University, Egypt.


During Gamete Micromanipulation sperms are injected into an ovum to assist in union of the gametes.


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Gametogenesis: a basic review
Anomalies of the female genital tract


Patient activation and consent form

Prior to commencing treatment the couple are interviewed by their gynecologist and any change in their medical condition is noted. The procedure of gamete micromanipulation is discussed in details and the routine investigations are done first. Once the patients have been activated, consent should be taken.
Consent forms need to cover the following areas : the technique of gamete micromanipulation, its potential complications, the inability to guarantee success and possible unknown ill effects on the resultant fetus. If excess embryos or eggs are to be frozen, special consent is obtained outlining the experimental nature of these procedure.
The main reason for having consent from the couple that have the possible complications explained and understood. As legal systems vary from country to country, it is advised that appropriate legal advice should be obtained before the consent forms are drafted.

Psychological Support

Most couples entering the gamete micromanipulation program have been through a long series of investigations. They often are depressed about their inability to conceive and not infrequently, one or other of the partners feels inadequate being unable to fulfill the spouse's desire for a child.

Sometimes there is pressure from one or the other partner that if the child is not produced then divorce may result. Many couples find that intercourse becomes a calculated compulsory activity and all elements of pleasure and recreation is removed. For all these, psychological support is essential to help couples to cope with these problems. The doctor plays the main role to eliminate the patient anxiety, anger and depression.

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