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Date of last update: 10/15/2017.

Forum Name: Liver Diseases

Question: Is there a safe amount of acetaminophen in cirrhosis?

 AilingBlackLab - Wed Sep 02, 2009 7:49 pm

I have read many conflicting opinions stating that people presenting early cirrhosis should avoid acetaminophen entirely , and have also read that in theraputic doses (the old guideline being 4,000mg per day max.) should be no problem even with existing liver disease. ...Now the FDA drops max to 3200mg ? is there a true concensus on what is safe in a patient with existing cirrhosis?
 Theresa Jones, RN - Tue Sep 29, 2009 7:27 am

User avatar Hi AilingBlackLab,
According to previous information provided by the American College of Gastroenterology acetaminophen should not exceed the package labeling. However new guidelines have been established by the FDA. You are correct in stating, people with liver disease should not exceed the FDA recommended limit of 3200mg. One of the reasons prompting the recommended lower dosage is because there are many other over the counter products that contain acetaminophen. People will take two acetaminophen tablets and then take Alka Seltzer Plus Cold for example, which also contains acetaminophen. There is a great deal of care recommended in reading package labeling and I would suggest that you not exceed the FDA recommendations. Best wishes!
Theresa Jones, RN

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