Medical Specialty >> Gastroenterology

Doctors Lounge - Gastroenterology Answers

Back to Gastroenterology Answers List

If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge ( does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.

DISCLAIMER: The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.

Date of last update: 10/15/2017.

Forum Name: Gastroenterology Topics


 Leena - Sat Sep 12, 2009 3:11 am

Dear Doctor:

Since July 2009, my friend Ani has been suffering severe diarrhea with nausea for weeks. Has other symptoms such as drastic weight loss and fatigue. Consulted gastroenterologist who performed endoscopy along with biopsies.

His UGI Endoscopy report findings:

Esophagus: Has 2 erosions at lower end, G. E. Junction at 39 cm, small hiatus hernia.

Stomach: Body, fundus, pylorus and antrum has erythema with congested greater curvature folds

Duodenum: D1 is normal and D2 has normal folds Gastric and D3 BC taken

Impression: GERD LA-B, small hiatus hernia

His Histopathology report results came as follows:


A. Duodenal mucosa is patchily eroded and contains moderate diffuse infiltrate of plasma cells, lymphocytes and eosinophils in the lamina propria.Villi and villous crypt ratio are near normal.Part of normal muscularis mucosae present. No Brunner glands, granuloma, collagenosis, or atypia noted.

B. Gastric mucosa is patchily eroded and has moderate diffuse infiltrate of plasma cells, lymphocytes and eosinophils in the oedematous lamina propria. Few glands are crowded showing mild dysplasia, regenerating activity and intestinal metaplasia. Focal distortion of glands present. Part of normal muscularis mucosae seen. No granuloma, collagenosis, increase in IEL or atypia noted. H.Pyloris seen.



1) Where it mentions "HELICOBACTOR ASSOCIATED CHRONIC GASTRITIS WITH PATCHY INTESTINAL METAPLASIA AND MILD DYSPLASIA," is there something to be extremely concerned about? Is this pre-cancerous or has it already progressed to cancer?

2) What type of treatment is recommended?

Currently having breathing difficulty and doctor said due to his stomach ailment. Currently taking Amoxicllin, Clarithromycin and Rabeprazole.

Need your esteemed opinion and advise, please

Thank you

 Dr.M.Aroon kamath - Tue Nov 03, 2009 2:31 am

User avatar Hi,
H.pylori can result in two types of gastritis..
- Antral predominant gastritis (may lead to peptic ulceration) or
- Multifocal atrophic gastritis (this may lead to a chronic atrophic gastritis - with areas of 'intestinal mataplasia'- increases the risk for gastric carcinomas).
H.pylori infection also increases the risk for gastric MALT lymphomas.

It does not mean however,that everyone who has Multifocal atrophic gastritis will develop a cancer.
In most people, it remains as atrophic gastritis. Only a small minority may develop a gastric cancer if they happen to have additional risk factors.
People living in areas where gastric cancer incidence is high are believed to be at a higher risk.
Best wishes!

| Check a doctor's response to similar questions

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us