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Date of last update: 10/14/2017.

Forum Name: Gynecology

Question: diphenhydramine and menstruation

 hmag_82 - Mon May 21, 2007 5:28 am

I have been taking diphenhydramine (over the counter sleep aid tablets) everynight for about six weeks straight, sometimes having to double the dosage. I did not get my period this month, it is about three weeks late and I am not pregnant. Can overuse of this drug be the cause?
 Dr. Chan Lowe - Mon May 21, 2007 5:55 pm

User avatar Diphenhydramine can have effects on the menstrual cycle. Absense of menses is not typically reported to happen with this drug. However, many things can affect the menstrual cycle, including poor sleep.

If you do not have a period next month you should see your gynecologist for an evaluation. Missing one period every now and then is relatively common.

Best wishes.

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