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Date of last update: 10/14/2017.

Forum Name: Obstetrics

Question: Nitrofurantoin and conception

 RoxRen - Thu Feb 03, 2005 8:55 am

I am currently trying to conceive. I am day 12 of my cycle ( normal 29 day cycles), and 3 days into a 7 day prescription for Nitrofurantoin to treat a bladder infection. I have read that this drug is sometimes related to male infertility and can affect sperm quality. Will this drug affect my vaginal secretions in such a way that sperm quality can degrade? Is it advisable to conceive while on this drug? Thanks.
 Dr. Anthony Solomon - Sun Feb 06, 2005 7:16 pm

The British National Formulary does not mention any side-effects of Nitrofurantoin associated with male infertilty or sperm quality. Rather, it advises that the drug should not be prescribed in pregnancy at term , impaired renal function , G6PD deficiency, and porphyria.

It is advisable not to conceive while on this drug because of unpleasant side-effects, notably loss of appetite, nausea, vomiting, diarrhoea, and hypersensitivity reactions.

Dr Anthony Solomon

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