Medical Specialty >> Gynecology

Doctors Lounge - Gynecology Answers

Back to Gynecology Answers List

If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge ( does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.

DISCLAIMER: The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.

Date of last update: 10/14/2017.

Forum Name: Obstetrics

Question: Amitriptyline during pregnancy

 bowskie - Wed Mar 10, 2010 8:48 am

How great a risk is there of complications with our babies development due to the medication Amitriptyline?

It was prescribed by our doctor for kidney stones (to control the number of times at night when my wife felt she needed to urinate) before we were aware of the pregnancy. It is likely that is was taken for the first 2-3 weeks of pregnancy.

I am worried that this might cause deformities in the baby, as I have read that some women who were pregnant and took it had this problem.
 Debbie Miller, RN - Tue Mar 30, 2010 12:36 am

User avatar Hello,
At that early point in development it is very unlikely the medication would cause any increased risk of birth defects. It is sometimes used when benefit outweighs the potential risks. Animal studies have linked this drug with birth defects and though animal studies are not good indicators of human response, we do recommend caution with this drug and pregnancy so discontinuing it is the safest course unless your doctor determines it is the best treatment for you.

Best wishes.

| Check a doctor's response to similar questions

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us