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Date of last update: 10/12/2017.

Forum Name: Hematology Topics

Question: Subclinical iron overload???

 siligurl - Wed Apr 08, 2009 3:27 pm

Last year my iron labs were way off (high). Docs did nothing with it. Just got retested and my labs are as follows:
Transferrin = 265 mg/dl
UIBC - 205 ug/dl
TIBC = 296 ug/dl
iron saturation = 31%
iron = 91 ug/dl

So I get that all those numbers are within normal range, but see that some are on the higher end of normal. Do I need to be concerned? I know that I have a lot of symptoms of hemochromatosis-- to include hypothyroidism, gall bladder disease w/o family history, liver damage, etc.-- and am curious as to whether subclinical iron overload could be a factor.

 Dr.M.jagesh kamath - Fri Oct 16, 2009 11:13 pm

User avatar Hello,Your investigations are normal.Haemochromatosis is a genetic condition in which the body absorbs more iron from the gut due to inability to stop when the reserves are full.If you are worried about this due to a family ho, you can undergo HFE gene test to look out for mutations.Generally transferrin saturations would give adequate proof.A repeat test would be best done and if normal would be helpful to make sure that there is no problem.Good wishes.

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