Medical Specialty >> Hematology

Doctors Lounge - Hematology Answers

Back to Hematology Answers List

If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge ( does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.

DISCLAIMER: The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.

Date of last update: 10/12/2017.

Forum Name: Hematology Topics

Question: giant platelets/low platelets bone marrow biopsy

 cootie1998 - Wed Sep 16, 2009 8:13 pm

My husband has had giant platelets for 2 years and was followed by a hematologist and had some testing for them and we were told to just watch them. Recently he had been feeling more tired than usual and we got sent back to the hematologist because now his platelets are still Giant but also low @ 111. He had a bone marrow biopsy earlier this week and we are going for platelet aggregation this friday. I realize we are most likely looking at a clotting disorder potentially but is leukemia or lymphoma a possibility also? As far as medical hx he has been treated for HTN for 2 years, he quite chewing snuff 2 years ago. Just want some ideas on how serious of an issue we are looking at? He returns to the doctor next week and we are really worried. Thanks for your time.
 Dr.M.jagesh kamath - Mon Nov 16, 2009 2:56 am

User avatar Hello,With giant platelets and low platelet count with out bleeding or clotting disorder one has to think of May-Hegglin anomaly in which giant platelets and inclusion bodies called dohle bodies are found in leucocytes.This is rare but not a serious condition and may not need treatment.Do get a consultation with your hematologist and you can discuss such a possiblity.Best wishes.

| Check a doctor's response to similar questions

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us