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Robert L. Coleman, MD's avatar

Rucaparib Maintenance Therapy Improves PFS in Platinum-sensitive Ovarian Cancer - The ARIEL3 Trial

Author: Robert L. Coleman, MD
Submitted: September 12, 2017.
Professor Robert L. Coleman M.D., FACOG, FACS discusses the implications of data from the Phase 3 ARIEL3 trial of the novel PARP inhibitor rucaparib as maintenance therapy in patients with platinum-sensitive ovarian cancer. Professor Coleman is the Vice… Read more...


Ted Lain, MD's avatar

Investigational Topical Minocycline Gel for Acne Advances to Phase III Development

Author: Ted Lain, MD
Submitted: May 25, 2017.
Clinical trial investigator Dr. Ted Lain comments on the results of the OPAL study, a Phase 2b clinical trial which evaluated the efficacy of a novel topical gel formulation of the antibiotic minocycline (BPX-01) in reducing the number of inflammatory… Read more...


Elizabeth M. Swisher, MD's avatar

Characterization of patients with ovarian carcinoma who respond to the PARP inhibitor rucaparib

Author: Elizabeth M. Swisher, MD
Submitted: April 12, 2017.
Dr. Elizabeth M. Swisher comments on the implications of new data from the ARIEL2 trial, an ongoing Phase 2 trial of the novel PARP inhibitor rucaparib in relapsed, high-grade serous or endometrioid ovarian cancer. The new results offer an important insight… Read more...


Bert Vogelstein, MD's avatar

Bert Vogelstein explains cancer and the unavoidable replicative mutations

Author: Bert Vogelstein, MD
Submitted: March 28, 2017.
Investigators at Johns Hopkins University in Baltimore used complex mathematical modeling to track mutations driving abnormal cell growth for 32 types of cancer. From their calculations, the researchers believe that the bulk of cancers are caused by random… Read more...


Tamer M. Fouad, M.D.'s avatar

Ebola Outbreak Highlights Struggle for Science in Africa and Inequalities in Global Health Research

Author: Tamer M. Fouad, M.D.
Submitted: November 13, 2014.
This article was first published on The Huffington Post by Dr. Tamer M. Fouad, M.D. Republished on Doctors Lounge with permission. Read more...


Dr. Alberto De la Guerra's avatar

Bevacizumab for breast cancer: FDA grants a stay of execution

Author: Dr. Alberto De la Guerra
Submitted: January 19, 2011.
The Food and Drug Administration has after repeated delays proposed removing metastatic breast cancer as an indication from the Avastin label. The proposal is being contested by Roche/Genentech, the drug’s maker. In this article we review the evidence… Read more...


Debbie Miller, RN's avatar

Pregnancy Weight Gain Guidelines in the US - a Historical Overview

Author: Debbie Miller, RN
Submitted: October 12, 2010.
Prior to the introduction of the medical community in the natural birth process, any maternal recommendations and guidelines were passed from mother to daughter or through lay midwives, herbal and folk practitioners. Childbirth, though risky, was not… Read more...


Dr. Alberto De la Guerra's avatar

New TNM Classification for Lung Cancer. Part II: A review

Author: Dr. Alberto De la Guerra
Submitted: February 07, 2010.
The American Joint Committee on Cancer and the Union Internationale Contre le Cancer have redefined the criteria for staging lung cancer based on the proposals made by the International Association for the Study of Lung Cancer, which appeared in the recently… Read more...


Dr. Alberto De la Guerra's avatar

New TNM Classification for Lung Cancer - Part I: The changes

Author: Dr. Alberto De la Guerra
Submitted: January 31, 2010.
Appropriate staging of lung cancer is fundamental for determining the best treatment approach and defining prognosis. After ten years of labor the IASLC has modernized the lung cancer TNM staging system. Revisions to the TNM were determined by differences… Read more...


Tamer M. Fouad, M.D.'s avatar

Improved survival in AML with higher anthracycline doses

Author: Tamer M. Fouad, M.D.
Submitted: September 29, 2009.
Younger patients with acute myeloid leukemia (AML) that receive higher doses of anthracyclines during induction chemotherapy are reported to have better complete remission rates in most studies. As of yet, studies have failed to show an improved surivival… Read more...


Jeffrey A. Gordon, M.D.'s avatar

Aspirin Use as Treatment in Colorectal Cancer: Teaching an Old Dog New Tricks

Author: Jeffrey A. Gordon, M.D.
Submitted: September 12, 2009.
Aspirin use can decrease the risk of colorectal adenomas.  Full-dose, but not low-dose, aspirin may decrease the risk of developing colorectal cancer.  Whether or not aspirin use can favorably augment survival in patients diagnosed with colorectal cancer… Read more...


Tamer M. Fouad, M.D.'s avatar

The Role of Chemotherapy in Advanced Estrogen Receptor Positive Breast Cancer

Author: Tamer M. Fouad, M.D.
Submitted: September 03, 2009.

Estrogen receptor positive (ER-positive) breast tumors account for approximately three-quarters of all new cases. Patients with advanced tumors are treated based on the presence of risk factors such as the presence of visceral metastasis, short disease… Read more...


Merlin C. Lowe, MD, FAAP's avatar

Have Resident Work Hour Restrictions Compromised Training - a Pediatrician’s Perspective

Author: Merlin C. Lowe, MD, FAAP
Submitted: August 26, 2009.

With many recent changes in residency requirements, one must wonder how effective our residency training system is. Are residents still learning the required information to perform well? Is the new system just as good as the old but in a "kinder" way?… Read more...


Tom Plamondon PA-C's avatar

Special tests in the clinical examination of patellofemoral syndrome

Author: Tom Plamondon PA-C
Submitted: August 12, 2009.

Patellofemoral Syndrome usually involves abnormal alignment of the knee or patella and excessive pull or imbalance of certain muscles around the knee. Therefore, it is important to evaluate certain biomechanical elements of the lower extremity. In… Read more...


Parks P, RN's avatar

Heparin Induced Thrombocytopenia - more common than believed

Author: Parks P, RN
Submitted: July 10, 2009.

Heparin induced thrombocytopenia (HIT) is a severe immune reaction to heparin. Heparin is the most common prescribed anticoagulant in the United States. HIT is a potentially fatal condition it can lead to amputation and loss of limbs; it is more common… Read more...


Theresa Jones, RN's avatar

No health insurance? Where to go during the financial crisis

Author: Theresa Jones, RN
Submitted: March 02, 2009.

As our healthcare crisis continues to rise, there is an increase in the population who are finding difficulty in accessing healthcare.

Read more...

Dr. K. Eisele's avatar

Antidepressants do they work? A Review of the Review

Author: Dr. K. Eisele
Submitted: July 27, 2008.
This article is in response to an announcement by researchers quoted in many UK publications this week, stating that the class of anti-depressants known as SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors)… Read more...


Debbie Miller, RN's avatar

Pregnancy Planning in the Weight Loss Surgery Patient

Author: Debbie Miller, RN
Submitted: November 20, 2007.
It has been documented that obesity in an expectant mother negatively affects her pregnancy. This can begin even before conception since infertility is a frequent problem associated with excess weight. In addition, pregnancy in an obese woman tends to… Read more...


Dr. Apurva Madia's avatar

Chest Pain in Young Females

Author: Dr. Apurva Madia
Submitted: May 26, 2006.

Chest pain is one of the common complaints heard in medical OPDs as well as at the GP's clinic. Chest pain causes a lot of anxiety in the patient as it is many a time related to "heart attack" or angina and people are quite aware of the serious consequences… Read more...


Dr. M. Mavru's avatar

Novel therapy combinations gain ground in treating hepatitis

Author: Dr. M. Mavru
Submitted: May 26, 2006.

According to recent estimates, hepatitis has become a worldwide health problem, affecting millions of people in the U.S. and abroad.

Read more...

R. Zein, Pharm D's avatar

Diabetic Nephropathy - Early intervention is the key!

Author: R. Zein, Pharm D
Submitted: March 15, 2006.
Diabetes has become the most common single cause of end-stage renal disease (ESRD) in the United States and worldwide. This is due to the fact that diabetes, in particular type 2 diabetes, is increasing in prevalence and patients with diabetes are living… Read more...


Dr. Safaa Mahmoud's avatar

Diabetics should receive statins, study says

Author: Dr. Safaa Mahmoud
Submitted: July 01, 2003.
Diabetes mellitus is a chronic disease caused by an inherited and/or acquired deficiency in production of insulin by the pancreas, or by ineffectiveness of the insulin produced. Such a deficiency results in increased concentrations of glucose in the blood,… Read more...


Dr. Hesham Al-Inany, MD's avatar

The ethical aspects of gamete micromanipulation

Author: Dr. Hesham Al-Inany, MD
Submitted: March 28, 2002.
Assisted reproductive technology (ART) is probably one of the most studied medical procedures from the moral point of view. Gamete micromanipulation involves new possibilities as well as new challenges. Read more...


Tamer M. Fouad, M.D.'s avatar

Percutaneous in-situ coronary venous arterialization (PICVA)

Author: Tamer M. Fouad, M.D.
Submitted: May 12, 2001.
Percutaneous in-situ coronary venous arterialization (PICVA) is gaining alot of attention recently. Especially after its initial success in saving the life of a patient suffering from cardiac infarction who was not candidate for CABG. However, as successful… Read more...


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