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Experimental Drug Slows Mental Decline in Alzheimer’s Patients

July 27, 2018. 12:00 PM CDT. However, the Phase 2 study of BAN2401 did not meet its primary end point Read article


ASCO: Endocrine Tx Noninferior for HR+, HER2− Breast Cancer

June 04, 2018 Similar efficacy for endocrine, chemoendocrine tx for women with midrange 21-gene recurrence score

ASCO: Sunitinib Alone Noninferior in Metastatic Renal Cell Cancer

June 04, 2018 Sunitinib alone noninferior to nephrectomy plus sunitinib with respect to overall survival

ASCO: Pembrolizumab Superior for Initial Tx of Advanced NSCLC

June 04, 2018 Improved overall survival versus chemotherapy regardless of the PD-L1 tumor proportion score

Dupilumab Reduces Rate of Severe Asthma Exacerbations

May 23, 2018 And, add-on dupilumab reduces glucocorticoid dose in patients with glucocorticoid-treated asthma

Procalcitonin Assay Doesn’t Cut Antibiotic Use in Lower RTI

May 22, 2018 Provision of assay doesn't result in less antibiotic use for suspected lower respiratory tract infection

AUA: Many Have Unused Opioids After Urologic Procedures

May 18, 2018 Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Clopidogrel + Aspirin Cuts Ischemic Events in Stroke, TIA

May 17, 2018 However, combination is associated with increased risk of major hemorrhage within 90 days

Alteplase Good for Ischemic Stroke With Unknown Onset Time

May 16, 2018 Better functional outcomes with alteplase, but small increased rate of intracranial hemorrhage

Executive Function Improved With Prenatal Exposure to SSRIs

May 07, 2018 Better EF skills in 12-year-olds exposed to prenatal SSRI, even controlling for maternal depressive sx

Opioids Often Over-Prescribed After Hiatal Hernia Surgery

May 02, 2018 Patients use fewer opioids than are prescribed after open, laparoscopic hiatal hernia repair

AAN: Cerliponase Alfa Beneficial for Form of Batten’s Disease

April 26, 2018 Reduced decline in motor, language function in children with CLN2 compared with historical controls

Study Finds 31 Percent Use No Opioids After Surgery

April 20, 2018 At discharge, 92.2 percent of patients received an opioid prescription; nearly 63 percent unused

Eight Factors Predict Pain After Spine Surgery

April 20, 2018 Post-op pain strongly linked to number of classes of non-opioid analgesics used, remifentanil use

AAN: Erenumab Shows Promise for Hard-to-Treat Migraine

April 19, 2018 Higher proportion of patients achieved a ≥50 percent reduction in mean monthly migraine days

AAN: New Drug May Help Infants With Spinal Muscular Atrophy

April 19, 2018 RG7916 increases survival motor neuron protein level, with 6.5-fold increase noted with highest dose