JOURNAL UPDATE

Low Serum Vitamin D Tied to Age-Related Loss of Muscle Strength

Findings for both 25-hydroxyvitamin D deficiency and insufficiency

• Bidirectional Association for Ménière Disease, Osteoporosis
• 2001 to 2021 Saw Decline in Physician Work Hours
• 2012 to 2021 Saw Drop in Bicycle-Related Injuries
• Metformin Use Linked to Lower Risk for Joint Replacement in T2DM

OTHER JOURNAL ARTICLES

Football Players Face Accelerated Aging

Findings show fewer years free of disease at all ages compared with the general population

Diet and Exercise Intervention Better for Pain in Knee Osteoarthritis

Among overweight or obese adults, diet and exercise led to small but significant difference in pain over 18 months versus attention control

Air Pollution Tied to Multimorbidity Status, Severity

Higher exposures to particulate matter and nitrogen dioxide associated with multimorbidity status in dose-dependent manner

Odds of Migraine Up With Median, Multiple Nerve Decompressions

Rates of migraine higher in association with median nerve decompression, multiple nerve decompressions

Preprint, Peer-Reviewed Pairs of Studies Generally Concordant

Sample sizes, primary end points, interpretations mainly concordant for studies published on medRxiv, then in journals

Antidepressants Have Small Benefit for Pain, Function in OA

However, total adverse events occur more often in patients receiving antidepressants versus placebo

FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’

Article describes inadequate oversight relating to development of COVID-19 vaccines and predating the pandemic

Multidimensional Factors Shaped Physician Stress During Pandemic

Physicians' perceptions of occupational stress at individual level were shaped by stressors within and across four levels

Outcomes Similar for Total Ankle Replacement, Ankle Fusion in OA

No clinically or statistically significant difference seen in mean change in Manchester-Oxford Foot Questionnaire walking/standing domain scores

Hip Brace May Slow Hip Displacement in Children With Cerebral Palsy

Improvements also seen in caregiver-reported quality of life for children with nonambulatory cerebral palsy

Delivery Methods Compared for Osteoarthritis Intervention

Pain reduction seen for in-person or digital delivery of education and exercise instruction for hip, knee osteoarthritis

CDC Updates Recommendations for Prescribing Opioids for Pain

Benefits and risk of all treatment options should be considered in the context of patient circumstances

Prevalence of Arthritis Higher Among Caregivers

Proportion of caregivers reporting disabilities was higher for those with versus without arthritis

Frailty-Related Fracture Risk Higher for Seniors With Cancer History

Cancer survivors who received chemotherapy more likely to have fracture; link stronger within five years of diagnosis

Antiseptics Work Equally Well in Preventing Infection After Surgery for Open Fractures

10 percent povidone-iodine and aqueous 4 percent chlorhexidine gluconate demonstrated similar efficacy in preventing infection after surgical fixation of open fractures