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JOURNAL UPDATE

Gastric Acid Suppressants May Up Risk of Recurrent C. difficile

March 27, 2017. 7:00 PM EST. Meta-analysis shows increased risk of recurrent CDI, even after adjustment for age and confounders Read article

OTHER JOURNAL ARTICLES

Increased Use of Newer Meds for Diabetic Nephropathy in the U.S.

March 27, 2017 DDP-4 inhibitors used in 54 percent of visits in last quarter of 2014; ACE inhibitors, ARBs often used

Recent Decline in Prescription Opioid Use Among U.S. Teens

March 24, 2017 Lifetime prevalence of use peaked in 1989, 2002, and remained stable until decline in 2013 to 2015

Inositol Supplements Don’t Prevent Gestational Diabetes

March 24, 2017 Findings among women with a family history of diabetes

30-Day Mortality Down During Joint Commission Survey Weeks

March 23, 2017 Patients admitted during survey weeks (versus non-survey weeks) have significantly lower mortality

Perinatal HIV Infection Down in U.S. From 2002 to 2013

March 23, 2017 37.5% of mothers had HIV infection diagnosed pre-pregnancy in 2002-2005, vs 51.5% in 2010-2013

Review: Treatment Options for Benzodiazepine Dependence

March 23, 2017 Good evidence for cognitive behavioral therapy and motivational approaches to dependence

C1 Inhibitor Use Reduces Attacks in Hereditary Angioedema

March 23, 2017 Subcutaneous CSL830 at doses of 40 and 60 IU reduce rate of attacks, need for rescue medication

Statin Intolerance Tied to Increased Risk of Recurrent MI

March 23, 2017 Higher rate of recurrent MI, coronary heart disease for Medicare beneficiaries post-MI hospitalization

CANA/PHEN Aids Weight Loss in Obese Without Type 2 Diabetes

March 23, 2017 Canagliflozin plus phentermine superior to placebo for weight loss at 26 weeks in obese, overweight

Pregabalin Doesn’t Cut Intensity of Sciatica-Linked Leg Pain

March 22, 2017 No significant difference in leg-pain intensity score at week eight or 52 for pregabalin, placebo

Vitamin E, Selenium Don’t Prevent Dementia in Older Men

March 22, 2017 No reduction in the incidence of dementia with supplements of vitamin E, selenium, or both

TV Ads for Testosterone Tied to Increased Testing, Tx in U.S. Men

March 22, 2017 Increases in rates of new testing, testosterone initiation, initiation without a recent test

Multiple Dosing Mitigates ASA Hyporesponsiveness After CABG

March 22, 2017 Multiple dosing more effective than ASA 81 or 325 mg once-daily for suppressing serum TXB2 formation

Opioid Users Incur Higher Costs After Elective Abdominal Surgery

March 22, 2017 Preoperative opioid use linked to increased likelihood of longer hospital stay, rate of 30-day readmission

Prenatal DHA Supplementation Doesn’t Increase IQ at Age 7

March 21, 2017 No between-group difference in measures of language, academic and executive functioning