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JOURNAL UPDATE

Lecanemab Reduced Markers of Amyloid in Early Alzheimer Disease

December 01, 2022. 12:00 AM CST.

Moderately less decline seen in cognition and function at 18 months with lecanemab versus placebo

By Elana Gotkine HealthDay Reporter Read article

OTHER JOURNAL ARTICLES

Six Additional Weeks of Rivaroxaban Reduces Recurrent VTE

November 30, 2022

Risk for recurrent venous thromboembolism reduced for patients with isolated distal DVT receiving six additional weeks of rivaroxaban


Benzodiazepine Exposure in Pregnancy Does Not Up Risk for ADHD, Autism

November 30, 2022

No significantly increased risk seen for ADHD or ASD with exposure to benzodiazepines during first, second, third trimester


Extended-Release Morphine Does Not Reduce Breathlessness in COPD

November 30, 2022

One week of extended-release morphine does not significantly reduce the intensity of worst breathlessness


Second Death in Trial of Experimental Alzheimer Drug Raising Concerns

November 29, 2022

Doctors suspect that by stripping away amyloid deposits, lecanemab weakens blood vessels and leaves them vulnerable to bleeds


Medical Masks Similar to N95 Respirators for Preventing COVID-19

November 29, 2022

No significant difference seen with medical masks versus N95 respirators for health care personnel providing care to COVID-19 patients


Risk of Uterine Diseases, Cancers Up With Tamoxifen Treatment

November 29, 2022

After adjustment for confounding variables, risk of endometrial cancer was increased almost fourfold with tamoxifen treatment


Combination Treatment Beneficial in Albuminuric CKD

November 29, 2022

7.4 year gain in event-free survival for 50-year-old patients with combo therapy with ACEi/ARB and SGLT2 inhibitors


Antidepressants Have Small Benefit for Pain, Function in OA

November 29, 2022

However, total adverse events occur more often in patients receiving antidepressants versus placebo


Studies Compare Various Treatments for COVID-19

November 28, 2022

Sotrovimab effective compared with molnupiravir; second study shows no effect for angiotensin receptor blockers in terms of illness severity


QOL Up With Pembrolizumab Versus Ipilimumab, HDI in Resected Melanoma

November 28, 2022

Quality of life favored the pembrolizumab arm versus standard-of-care arm receiving ipilimumab, high-dose interferon α 2b


Benzodiazepines Tied to Drug Overdose in Young People With Sleep Disorders

November 28, 2022

Findings even stronger for young people with a recent opioid prescription


Measles Vaccination Rates Dropped During Pandemic to 81 Percent in 2021

November 23, 2022

Number of estimated measles deaths decreased 83 percent during 2000 to 2021; estimated 56 million deaths prevented by vaccination


Early Application of Emollients Prevents Development of Eczema

November 23, 2022

Of the types of emollient, emulsion was suggested as the better option for preventing infant atopic dermatitis development


Flu Shots Cut Some Cardiac Complications in Patients With Heart Failure

November 23, 2022

Less pneumonia, fewer cardiovascular events, deaths, hospitalizations seen during peak flu season


Outreach Messages Up Well-Child Visits, Vaccination Completion

November 22, 2022

Rates of scheduling and completion of well-child visits increased regardless of whether messages were standard or tailored