Create Account | Sign In: Author or Forum

Search Symptoms

Category: Family Medicine | Internal Medicine | Orthopedics | Pharmacy | Journal

Back to Journal Articles

Vitamin D Supplementation No Aid to Muscle Health

Last Updated: August 30, 2021.

MONDAY, Aug. 30, 2021 (HealthDay News) -- Vitamin D supplementation does not show a benefit to muscle health, according to a review published online Aug. 17 in the Journal of Bone and Mineral Research.

Lise Sofie Bislev, M.D., Ph.D., from the Aarhus University Hospital in Denmark, and colleagues conducted a systematic literature review to identify studies investigating the effects of vitamin D supplementation versus placebo on muscle health.

Based upon 54 randomized controlled trials (including 8,747 individuals), the researchers found that vitamin D was associated with a significantly longer time spent performing the timed up and go test versus placebo (19 studies, I2 = 0 percent). Vitamin D was also associated with a significant lower maximum knee flexion strength (12 studies, I2 = 0 percent). In response to vitamin D, the Short Physical Performance Battery showed a tendency toward worsening versus placebo (eight studies). No other measures of muscle health showed between-group differences.

"Care should be taken recommending vitamin D supplementation to improve muscle strength and function in people with normal or only slightly impaired vitamin D status," Bislev said in a statement. "We need to study further whether it may benefit muscles in those with severe vitamin D deficiency, however."

Abstract/Full Text (subscription or payment may be required)


Previous: Obesity Ups Medical Spending for Long-Term Cancer Survivors Next: Ultra-Low-Dose Combo Cuts Systolic BP in Hypertension

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion: