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October 2011 Briefing - Allergy

Last Updated: November 01, 2011.

Here are what the editors at HealthDay consider to be the most important developments in Allergy for October 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Switching From IV to Oral Meds Cuts Health Care Costs

MONDAY, Oct. 31 (HealthDay News) -- For patients who are clinically eligible for oral (PO) medication intake, switching from intravenous (IV) to oral medication can substantially reduce the annual cost of health care, according to a study published online Oct. 17 in Clinical Therapeutics.

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Fecal Assays Help Identify Food Hypersensitivity in IBS

FRIDAY, Oct. 28 (HealthDay News) -- A quarter of patients with irritable bowel syndrome (IBS) have food hypersensitivity (FH), which can be detected using fecal assays; most accurately with eosinophil cationic protein (ECP) assay, according to a study published in the November issue of Clinical Gastroenterology and Hepatology.

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Ghost Authorship Prevalent in About One-Fifth of Articles

WEDNESDAY, Oct. 26 (HealthDay News) -- The prevalence of articles with honorary authorship, ghost authorship, or both is 21 percent, which marks a significant decrease since 1996, according to a study published online Oct. 25 in BMJ.

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LABA Use Ups Risk of Serious Asthma Events in Children

MONDAY, Oct. 24 (HealthDay News) -- The use of long acting β²-adrenergic receptor agonists (LABAs) in children increases the risk for an excess of serious asthma-related events, according to a study published online Oct. 24 in Pediatrics.

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H. pylori Not Detected in Hyperplastic Adenoids

WEDNESDAY, Oct. 19 (HealthDay News) -- Helicobacter pylori (H. pylori) and other Helicobacteraceae family members do not majorly contribute toward development of hyperplastic adenoids in children, according to a study published in the October issue of the Archives of Otolaryngology -- Head & Neck Surgery.

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Different CD8+ T-Cell Targets in New, Established Diabetes

WEDNESDAY, Oct. 19 (HealthDay News) -- Autoreactive CD8+ T cells specific for preproinsulin (PPI) include central and effector memory cells and show different specificities for epitopes in patients with recent-onset and long-standing type 1 diabetes (T1D), according to a study published online Oct. 13 in Diabetes.

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Readmission Risk Models Display Poor Predictive Ability

TUESDAY, Oct. 18 (HealthDay News) -- Most hospital readmission risk models have poor predictive ability, according to a review published in the Oct. 19 issue of the Journal of the American Medical Association.

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Vitamin D-Gene Interaction Tied to Food Sensitization

FRIDAY, Oct. 14 (HealthDay News) -- Vitamin D deficiency (VDD) increases the risk of food sensitization (FS) in children carrying specific genotypes, according to a study published in the November issue of Allergy.

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Pediatric Asthma Drug Prescriptions on the Upswing

THURSDAY, Oct. 13 (HealthDay News) -- Among children, the use of medications to control asthma nearly doubled in the last decade, while costs associated with all asthma medications more than quadrupled, according to a September statistical brief published by the Agency for Healthcare Research and Quality (AHRQ).

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Rare Disorders ID'd by NIH Undiagnosed Diseases Program

THURSDAY, Oct. 13 (HealthDay News) -- The extensive application of genomic technology under the U.S. National Institutes of Health Undiagnosed Diseases Program (NIH-UDP) helps diagnose complex and rare multisystem disorders, according to a report published online Sept. 26 in Genetics in Medicine.

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Vitamin D Dependent Pathway Key in Immunity Against TB

THURSDAY, Oct. 13 (HealthDay News) -- Interferon-γ (IFN-γ) released by T cells induces multiple macrophage responses to Mycobacterium tuberculosis in in a vitamin D-dependent pathway, according to a study published in the Oct. 12 issue of Science Translational Medicine.

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Financial Conflicts of Interest Prevalent, Under-Reported

WEDNESDAY, Oct. 12 (HealthDay News) -- Conflicts of interest (COI) are prevalent among members and chairs of guideline panels, and are under-reported, according to a study published online Oct. 11 in BMJ.

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More Minority Patients in Low-Quality, High-Cost Hospitals

THURSDAY, Oct. 6 (HealthDay News) -- Hospitals where the quality is low and costs high (worst hospitals) in the United States care for a higher proportion of elderly black, Hispanic, and Medicaid patients than high-quality, low-cost institutions (best hospitals), according to a study published in the October issue of Health Affairs.

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High Children's Asthma Care Compliance in Peds Hospitals

TUESDAY, Oct. 4 (HealthDay News) -- For children admitted with asthma to pediatric hospitals, there are high levels of hospital compliance with Children's Asthma Care (CAC) quality measures for receiving asthma relievers (CAC-1) and systemic corticosteroids (CAC-2), and moderate compliance for discharge with a home-management care plan (CAC-3), according to a study published in the Oct. 5 issue of the Journal of the American Medical Association.

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