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Category: Pulmonology | Monthly Briefing

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December 2011 Briefing - Pulmonology

Last Updated: January 02, 2012.

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for December 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Oseltamivir-Resistant H1N1 Identified in Australia

THURSDAY, Dec. 29 (HealthDay News) -- Oseltamivir-resistant prepandemic seasonal influenza 1 (H1N1) viruses with a neuraminidase substitution (H275Y) (A[H1N1]pdm09) have been identified in Australia, according to a letter published in the Dec. 29 issue of the New England Journal of Medicine.

Letter

Enoxaparin Doesn't Reduce Death Rate for Acutely Ill

WEDNESDAY, Dec. 28 (HealthDay News) -- For hospitalized, acutely ill medical patients, use of enoxaparin plus elastic stockings with graduated compressions, does not reduce the rate of death from any cause at 30 days, according to a study published in the Dec. 29 issue of the New England Journal of Medicine.

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Rhinoviruses Frequently Cause ARIs in VLBW Premature Infants

WEDNESDAY, Dec. 28 (HealthDay News) -- More than half (55 percent) of very low birth weight (VLBW) infants with acute respiratory illness (ARI) have infection with human rhinoviruses (HRVs), according to a study published online Dec. 26 in Pediatrics.

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Perceptions of Inappropriate Care Prevalent Among ICU Staff

TUESDAY, Dec. 27 (HealthDay News) -- Perceptions of inappropriate care are prevalent among intensive care unit (ICU) clinicians in Europe and Israel, according to a study published in the Dec. 28 issue of the Journal of the American Medical Association.

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Smoking During Pregnancy Affects Children's Vasculature

TUESDAY, Dec. 27 (HealthDay News) -- Parental smoking during pregnancy affects children's arterial structure and function in early life; and interventions that encourage parents to quit smoking for their children's benefit may increase parental quit rates, according to two studies published online Dec. 26 in Pediatrics.

Abstract - Geerts
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Abstract - Rosen
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Tobacco Smoke Ups Aspirin-Exacerbated Respiratory Disease

THURSDAY, Dec. 22 (HealthDay News) -- Active smoking, and combined childhood and adulthood exposure to environmental tobacco smoke (ETS) are associated with significantly higher odds of developing aspirin-exacerbated respiratory disease (AERD), according to a study published in the January issue of the Annals of Allergy, Asthma & Immunology.

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Sleep Disorders Tied to Adverse Health Outcomes for Police

TUESDAY, Dec. 20 (HealthDay News) -- Sleep disorders are common among police officers and are associated with adverse health, safety, and performance outcomes, according to a study published in the Dec. 21 issue of the Journal of the American Medical Association.

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Little Risk to Offspring From Maternal Inhaled Steroids

TUESDAY, Dec. 20 (HealthDay News) -- In pregnant women with asthma, the use of inhaled glucocorticoids does not increase the risk of most pediatric diseases in the offspring, though it may be a risk factor for endocrine and metabolic disorders, according to research published online Dec. 16 in the American Journal of Respiratory and Critical Care Medicine.

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Palivizumab Often Prescribed Improperly in Primary Practice

TUESDAY, Dec. 20 (HealthDay News) -- Physician oversight and education improves adherence to patient selection guidelines for palivizumab use, but fails to improve improper dosing, according to a study published online Dec. 19 in Pediatrics.

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Inhaled Dry Powder Mannitol Improves Lung Function in CF

TUESDAY, Dec. 20 (HealthDay News) -- Adding the inhaled dry powder mannitol to standard therapy for cystic fibrosis produces sustained improvement in lung function for up to 52 weeks, according to a study published online Dec. 16 in the American Journal of Respiratory and Critical Care Medicine.

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Physician Opinions on Benefits of Open Visit Notes Vary

MONDAY, Dec. 19 (HealthDay News) -- Primary care physicians (PCPs) have varied opinions about open access to doctors' notes; and most users of a personal health record (PHR) system are interested in sharing access to their information, according to two studies published in the Dec. 20 issue of the Annals of Internal Medicine.

Abstract - Walker
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Abstract - Zulman
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High BMI Up to Age 4 Does Not Impact School-Age Asthma Risk

MONDAY, Dec. 19 (HealthDay News) -- Having a high body mass index (BMI) in the first four years of life does not impact asthma risk at age 8 for those whose BMI normalizes by age 7 years, according to a study published online Dec. 19 in Pediatrics.

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Quitting Smoking Improves Happiness, Quality of Life

FRIDAY, Dec. 16 (HealthDay News) -- People who successfully quit smoking are happier and more satisfied with their lives than people who continue to smoke, according to a study published online Dec. 10 in the Annals of Behavioral Medicine.

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Patient Isolation During Hospitalization Tied to Delirium

FRIDAY, Dec. 16 (HealthDay News) -- Patients who are newly placed under contact precautions during hospitalization are at a higher risk for delirium, according to a study published in the January issue of Infection Control and Hospital Epidemiology.

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Asthma Strongly Associated With Chronic Rhinosinusitis

FRIDAY, Dec. 16 (HealthDay News) -- Asthma is strongly associated with chronic rhinosinusitis and its prevalence varies widely across Europe, according to the results of a multicenter, international study published in the January issue of Allergy.

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SNP in MTHFR Tied to Risk of Radiation Pneumonitis

FRIDAY, Dec. 16 (HealthDay News) -- In patients treated with thoracic radiation therapy for locally advanced lung cancer, a single-nucleotide polymorphism (SNP) in the methylene tetrahydrofolate reductase (MTHFR) gene is associated with a clinically significant risk of radiation pneumonitis (RP), according to a study published online Dec. 5 in Cancer.

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Smoking Linked to Non-Melanoma Skin Cancer

THURSDAY, Dec. 15 (HealthDay News) -- Non-melanoma skin cancer (NMSC) patients are twice as likely to have ever smoked compared to those with no past or present history of skin cancer, according to research published online Nov. 19 in Cancer Causes and Control.

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Statins Lower Death Risk in Adults Hospitalized With Flu

THURSDAY, Dec. 15 (HealthDay News) -- In adults hospitalized for influenza virus infections, administration of statins before or during the hospitalization is associated with a reduced risk of mortality, according to a study published online Dec. 13 in the Journal of Infectious Diseases.

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CPAP Improves BP, Metabolic Abnormalities in Sleep Apnea

WEDNESDAY, Dec. 14 (HealthDay News) -- For patients with severe obstructive sleep apnea, three months of continuous positive airway pressure (CPAP) therapy is associated with reduced blood pressure, and partial reversal of metabolic abnormalities, according to a study published in the Dec. 15 issue of the New England Journal of Medicine.

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Regional Rehospitalization Rate Tied to Overall Admissions

WEDNESDAY, Dec. 14 (HealthDay News) -- For patients with congestive heart failure or pneumonia, regional rates of rehospitalizations are substantially associated with overall admission rates at 30, 60, and 90 days, according to a study published in the Dec. 15 issue of the New England Journal of Medicine.

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Infection Prevention Up in VA, Non-Federal Hospitals

TUESDAY, Dec. 13 (HealthDay News) -- From 2005 to 2009, there was a significant increase in the use of hospital-acquired infection (HAI) prevention practices in non-federal and Veterans Affairs (VA) hospitals, according to a study published online Dec. 6 in the Journal of General Internal Medicine.

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Intravenous Salbutamol Ups Mortality in Early ARDS

MONDAY, Dec. 12 (HealthDay News) -- For patients with acute respiratory distress syndrome (ARDS), treatment with intravenous salbutamol in the early course of disease is associated with a significant increase in 28-day mortality, according to a study published online Dec. 12 in The Lancet.

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Editorial (subscription or payment may be required)

Depression, Physical Impairment Common After Lung Injury

FRIDAY, Dec. 9 (HealthDay News) -- During the first two years after acute lung injury (ALI), incident depressive symptoms and physical impairment are common and long-lasting, according to a study published online Dec. 8 in the American Journal of Respiratory and Critical Care Medicine.

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Factors Affecting Micro-RNA Detection Accuracy Identified

FRIDAY, Dec. 9 (HealthDay News) -- Accurate detection and quantitation of circulating microRNAs (miRNAs) is affected by inherent differences in plasma samples, methods used for their collection and analysis, and the presence of specific inhibitors in plasma, according to a study published online Dec. 9 in the Journal of Molecular Diagnostics.

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Seasonal Flu Activity Low in the United States So Far

THURSDAY, Dec. 8 (HealthDay News) -- Reports of influenza virus in the Unites States have been low for the first part of the influenza season, according to a summary published in the Dec. 9 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Hong Kong Dust Storms Up Emergency COPD Admissions

THURSDAY, Dec. 8 (HealthDay News) -- There is a significant correlation between dust storms and chronic obstructive pulmonary disease (COPD)-related emergency hospital admissions two days later, according to a study published online Aug. 24 in Respirology.

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Rifapentine Plus Isoniazid Noninferior to Isoniazid Alone

WEDNESDAY, Dec. 7 (HealthDay News) -- In individuals at high-risk for tuberculosis, three months of combination therapy with rifapentine plus isoniazid is as effective as nine months of isoniazid alone, and has significantly higher treatment completion rates, according to a study published in the Dec. 8 issue of the New England Journal of Medicine.

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Preventive Asthma Medication Use Increasing in Children

TUESDAY, Dec. 6 (HealthDay News) -- Use of preventive asthma medications (PAMs) among children with current asthma increased significantly from 1988 to 2008, but disparities persisted, with lower PAM usage reported among minority children, adolescents, and the uninsured, according to a study published online Dec. 5 in Pediatrics .

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Cardiorespiratory Fitness, Not BMI, Linked to Mortality

MONDAY, Dec. 5 (HealthDay News) -- Men who maintain or improve their cardiorespiratory fitness (fitness) have a reduced risk of all-cause and cardiovascular disease (CVD) mortality, irrespective of body mass index (BMI) change, according to a study published in the Dec. 6 issue of Circulation.

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Medical Students Fail to ID Hand Hygiene Indications

MONDAY, Dec. 5 (HealthDay News) -- Medical students who are about to start the clinical phase of their education have a lack of knowledge regarding the correct indications for hand disinfection, according to a study published in the December issue of the American Journal of Infection Control.

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Hypoglossal Stimulation Boosts Airflow in Sleep Apnea

THURSDAY, Dec. 1 (HealthDay News) -- For patients with obstructive sleep apnea (OSA), hypoglossal nerve simulation (HGNS) produces marked dose-related increases in airflow, without arousing patients from sleep, according to a study published online Nov. 25 in the American Journal of Respiratory and Critical Care Medicine.

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