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November 2012 Briefing - Gastroenterology

Last Updated: December 03, 2012.

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for November 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Aspirin Use Cuts Risk of Hepatocellular Carcinoma

THURSDAY, Nov. 29 (HealthDay News) -- For men and women aged 50 to 71, use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly aspirin, is associated with a reduced risk of hepatocellular carcinoma (HCC) and death due to chronic liver disease (CLD), according to a study published online Nov. 28 in the Journal of the National Cancer Institute.

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Removal of Consultation Fees Increased Spending on Doc Visits

WEDNESDAY, Nov. 28 (HealthDay News) -- The 2010 Medicare elimination of consultation payments (mainly billed by specialists) led to a net increase in spending on physician office visits, according to a study published online Nov. 26 in the Archives of Internal Medicine.

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Political Leaders Face Voter Opposition to Medicare Cuts

WEDNESDAY, Nov. 28 (HealthDay News) -- The majority of those who voted for President Obama in the 2012 election favor implementing the Affordable Care Act (ACA), while those who voted for Republican officeholders are likely to oppose parts or all of the implementation of the ACA; both sides oppose cuts to Medicare as a means to balance the budget, according to an analysis of newly released polls published as a Special Report online Nov. 28 in the New England Journal of Medicine.

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State Cost of Affordable Care Act's Medicaid Expansion Modest

WEDNESDAY, Nov. 28 (HealthDay News) -- Implementation of the Affordable Care Act's (ACA) Medicaid expansion will likely result in modest state costs by 2022, but will gain health care coverage for more than 20 million uninsured Americans, according to report published by the Kaiser Family Foundation.

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USPSTF: Consider Screening Baby Boomers for Hepatitis C Infection

TUESDAY, Nov. 27 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends that certain high-risk people be screened for the hepatitis C virus (HCV) and that screening should be considered for people born between 1945 and 1965. This Recommendation Statement is based on an evidence review published in the Nov. 27 issue of the Annals of Internal Medicine.

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Doc Earnings Growth Lags Behind Other Health Professionals

TUESDAY, Nov. 27 (HealthDay News) -- Compared with other health professionals, in the last 15 years there has been considerably less growth in the earnings of physicians in the United States, according to a research letter published in the Nov. 28 issue the Journal of the American Medical Association.

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Growing Number of Drugs Possibly Inhibited by Grapefruit

TUESDAY, Nov. 27 (HealthDay News) -- There are increasing numbers of newly marketed drugs that have the potential to interact with grapefruit, all of which are metabolized by the cytochrome P450 3A4 enzyme (CYP3A4), according to a review published online Nov. 26 in CMAJ, the journal of the Canadian Medical Association.

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Regorafenib Efficacious in GI Malignant Disease

FRIDAY, Nov. 23 (HealthDay News) -- For patients with metastatic colorectal cancer or gastrointestinal stromal tumors (GIST) who have progressed in spite of treatment, the multikinase inhibitor regorafenib may improve survival, according to the results of two phase 3 studies published online Nov. 22 in The Lancet.

Abstract - Grothey
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Abstract - Demetri
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Obama Administration Moving Forward With Health Care Law

WEDNESDAY, Nov. 21 (HealthDay News) -- Three rules have been proposed by the Obama administration to further facilitate implementation of the Affordable Care Act, according to a Nov. 20 press release from the U.S. Centers for Medicare & Medicaid Services.

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Tractable Preclinical Model Proposed for Ulcerative Colitis

MONDAY, Nov. 19 (HealthDay News) -- A parasitic worm can improve chronic diarrhea in monkeys by altering the immune response and bacterial species present in the intestine, providing a possible preclinical model for the treatment of ulcerative colitis, according to research published online Nov. 15 in PLOS Pathogens.

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Repeat Testing Common Among Medicare Beneficiaries

MONDAY, Nov. 19 (HealthDay News) -- For Medicare beneficiaries, repeat testing within three years is common, according to a study published online Nov. 19 in the Archives of Internal Medicine.

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Mental Illness, Job Stress Both Factors in Physician Suicides

FRIDAY, Nov. 16 (HealthDay News) -- The presence of mental illness or job problems may make physicians more vulnerable to suicide than non-physicians, according to a study published online Nov. 5 in General Hospital Psychiatry.

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Gene Variants ID'd in Alcohol-Related, Sporadic Pancreatitis

FRIDAY, Nov. 16 (HealthDay News) -- Two common genetic risk modifiers have been characterized for sporadic and alcohol-related chronic pancreatitis, according to a study published online Nov. 11 in Nature Genetics.

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Nucleoside Analogue Tx Cuts Recurrence in HBV-Related HCC

MONDAY, Nov. 12 (HealthDay News) -- For patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) who undergo curative liver resection, treatment with nucleoside analogues correlates with a reduced risk of HCC recurrence or death, according to a study published online Nov. 12 in the Journal of the American Medical Association to coincide with presentation at the annual meeting of the American Association for the Study of Liver Diseases, held from Nov. 9 to 13 in Boston.

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Social Network Profile May Harm Medical Applicants

MONDAY, Nov. 12 (HealthDay News) -- Social networking profiles may harm an applicant's chances of admission to medical school or a residency program, according to a study published online Nov. 8 in the Postgraduate Medical Journal.

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High Glycemic Load Linked to Worse Colon Cancer Survival

THURSDAY, Nov. 8 (HealthDay News) -- Patients with advanced colon cancer with high glycemic load and who consume high levels of carbohydrates during and after chemotherapy have worse survival, according to a study published online Nov. 7 in the Journal of the National Cancer Institute.

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QoL Up for Live Liver Donors Versus General Population

TUESDAY, Nov. 6 (HealthDay News) -- Living liver donors from Japan have higher health-related quality of life (HRQOL) than the Japanese norm population, according to a study published in the November issue of Liver Transplantation.

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Racial/Ethnic Discrepancies in HIV/HCV Liver-Related Mortality

MONDAY, Nov. 5 (HealthDay News) -- African-American women co-infected with HIV and hepatitis C virus (HCV) are significantly less likely to die from liver disease compared with Caucasian and Hispanic women, according to a study published in the November issue of Hepatology.

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Additional Genes Linked to Inflammatory Bowel Disease

FRIDAY, Nov. 2 (HealthDay News) -- A total of 163 genetic loci are associated with inflammatory bowel disease, many of which are implicated in other immune diseases and in the response against bacterial infection, according to a study published in the Nov. 1 issue of Nature.

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Patch Testing Can ID Food, Additives That Contribute to IBS

THURSDAY, Nov. 1 (HealthDay News) -- Patch testing may identify allergies to food or food additives that may be responsible for the symptoms of irritable bowel syndrome (IBS), according to a study published online Oct. 26 in the Journal of the American Academy of Dermatology.

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