Create Account | Sign In: Author or Forum

Search Symptoms

Category: Family Medicine | Pediatrics | Pulmonology | Allergy | Journal

Back to Journal Articles

Vitamin D Linked to Asthma Severity in Children

Last Updated: April 27, 2009.

Vitamin D insufficiency is present in about one-third of Costa Rican children with asthma and correlates with asthma severity, researchers report in the May 1 issue of the American Journal of Respiratory and Critical Care Medicine.

MONDAY, April 27 (HealthDay News) -- Vitamin D insufficiency is present in about one-third of Costa Rican children with asthma and correlates with asthma severity, researchers report in the May 1 issue of the American Journal of Respiratory and Critical Care Medicine.

John M. Brehm, M.D., from Brigham and Women's Hospital in Boston, and colleagues measured serum 25-hydroxyvitamin D levels and markers of allergy and asthma severity in 616 Costa Rican children with asthma aged 6 to 14 years.

The researchers found that 28 percent of children had insufficient levels of 25-hydroxyvitamin D (less than 30 ng/mL). After adjusting for possible confounding factors, low 25-hydroxyvitamin D levels were associated with high levels of IgE and eosinophils. Each 10-fold increase in 25-hydroxyvitamin D levels was associated with a reduced risk of hospitalization in the previous year (odds ratio, 0.05), use of anti-inflammatory drugs in the previous year (OR, 0.18), and increased methacholine airway responsiveness (OR, 0.15).

"Our results suggest that vitamin D insufficiency is relatively frequent in an equatorial population of children with asthma," Brehm and colleagues conclude.

Authors of the study report financial relationships with the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)
Editorial


Previous: AUA: Diet 7-Up + Pomegranate Juice = A Urologist Cocktail Next: AUA: Nighttime Urination Linked to Death in Elderly

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion: