Breech Presentation Linked to Autism Spectrum DisordersLast Updated: April 29, 2009. An association between breech presentation and autism spectrum disorders in children may point to a shared etiology between the two, according to research published in the May issue of Pediatrics.
WEDNESDAY, April 29 (HealthDay News) -- An association between breech presentation and autism spectrum disorders (ASD) in children may point to a shared etiology between the two, according to research published in the May issue of Pediatrics.
Deborah Bilder, M.D., of the University of Utah School of Medicine in Salt Lake City, and colleagues analyzed birth certificate records from 132 children, aged 8 years, who met the criteria for ASD. Each child was matched by birth year and gender to 100 controls.
The researchers found that children born to mothers who were at least 35 years of age had a greater likelihood of ASD than children of women who were 20 to 34 (odds ratio, 1.68). Children with autism were also more likely to be the first born (odds ratio, 1.79) and more likely to have a breech presentation (adjusted odds ratio, 2.10). Birth weight and five-minute Apgar scores were not linked to higher ASD risk, the authors note.
"The findings of this study suggest that maternal age, parity, and breech presentation are independently associated with ASD risk. Additional investigations focused on both genetic and environmental factors that link these factors individually or collectively are necessary. Identifying associations with other medical disorders may aid in the search for the cause of idiopathic autism as well as guide health care maintenance for children with autism," Bilder and colleagues conclude.
Two co-authors disclosed a connection to BioMarin's Autism Advisory Board.
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