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July 2017 Briefing - Pharmacy

Last Updated: August 01, 2017.

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for July 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Opioid-Related Fatal Car Crashes Up 7-Fold in Last Two Decades

MONDAY, July 31, 2017 (HealthDay News) -- There has been a seven-fold increase in the number of drivers killed in car crashes while under the influence of prescription opioids, according to a report published online July 20 in the American Journal of Public Health.

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Pre-Op Methylprednisolone Beneficial in Knee Arthroplasty

MONDAY, July 31, 2017 (HealthDay News) -- For patients undergoing elective unilateral total knee arthroplasty, preoperative administration of methylprednisolone is associated with reduced circulating markers of endothelial activation and damage, according to a study published online July 28 in Anaesthesia.

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Cost-Effectiveness of Allergen Immunotherapy Evaluated

MONDAY, July 31, 2017 (HealthDay News) -- Allergen immunotherapy (AIT) may be cost-effective for allergic rhinitis, and for venom allergy in high-risk subgroups, according to research published online July 18 in Allergy.

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Respiratory Microbiome May Influence Inflammation in CF

MONDAY, July 31, 2017 (HealthDay News) -- Reduced bacterial diversity in the upper and lower airways in infants with cystic fibrosis (CF) is associated with use of prophylactic antibiotics and younger age at sampling, while less diversity in lavage samples is associated with lower inflammation, according to a study published online July 14 in the Annals of the American Thoracic Society.

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Outbreak of Septic Arthritis Described in New Jersey

MONDAY, July 31, 2017 (HealthDay News) -- In a report published in the July 28 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report, details are presented of an outbreak of septic arthritis associated with intra-articular injections at a New Jersey outpatient practice.

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More Progress Needed for Hep C Elimination in Country of Georgia

MONDAY, July 31, 2017 (HealthDay News) -- More interventions are needed to meet the target of hepatitis C virus (HCV) elimination, defined as a 90 percent reduction in prevalence by 2020, in the country of Georgia, according to research published in the July 28 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Chemo Plus Hyperthermia Active in Advanced Pancreatic Cancer

MONDAY, July 31, 2017 (HealthDay News) -- For patients with locally advanced or metastatic pancreatic carcinoma with malignant ascites, a combined systemic and intraperitoneal chemotherapy approach plus hyperthermia is well tolerated and active, according to a study published online July 25 in the Journal of Global Oncology.

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FDA Proposes Lowering Nicotine Levels in Cigarettes

MONDAY, July 31, 2017 (HealthDay News) -- The U.S. Food and Drug Administration plans to begin a public dialogue about reducing nicotine levels in combustible cigarettes to non-addictive levels through achievable product standards, agency officials said Friday.

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Switching to Generic Eye Meds Could Save Medicare Millions

FRIDAY, July 28, 2017 (HealthDay News) -- Prescribing generic drugs for seniors' eye problems could save the U.S. government hundreds of millions of dollars a year, according to a study published recently in Ophthalmology.

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Thyroid Cancer Tied to Regular Thyroxine Use in Hypothyroidism

FRIDAY, July 28, 2017 (HealthDay News) -- Patients with primary hypothyroidism who are regular thyroxine users have increased risk of thyroid cancer, according to a study published online July 19 in the Journal of Clinical Pharmacology.

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ACOG: Opioid Agonist Rx First Choice in Affected Pregnancies

FRIDAY, July 28, 2017 (HealthDay News) -- While opioid agonist pharmacotherapy continues to be the recommended therapy for pregnant women with an opioid use disorder, medically supervised withdrawal can be considered under the care of a physician experienced in perinatal addiction treatment and with informed consent, according to a committee opinion published in the August issue of Obstetrics & Gynecology.

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Gene Expression May Predict Response to Methotrexate in RA

FRIDAY, July 28, 2017 (HealthDay News) -- For patients with rheumatoid arthritis (RA), increased baseline gene expression of p21, caspase 3, and runt-related transcription factor (RUNX)2 in the peripheral blood may be associated with improved clinical response to methotrexate (MTX), according to a study published online July 25 in the International Journal of Rheumatic Diseases.

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Variation in Management for Infants With GERD

FRIDAY, July 28, 2017 (HealthDay News) -- For infants with gastroesophageal reflux disease (GERD), there is considerable variation in diagnostic testing and surgical utilization, according to a study published online July 28 in Pediatrics.

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Morphine Effects Similar to Placebo in Rheumatoid Arthritis

THURSDAY, July 27, 2017 (HealthDay News) -- For patients with chronic fatigue syndrome (CFS)/fibromyalgia (FM) or rheumatoid arthritis (RA), morphine has anti-hyperalgesic effects comparable to placebo, according to a study published online July 19 in PAIN Practice.

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Tocilizumab Effective for Treatment of Giant-Cell Arteritis

THURSDAY, July 27, 2017 (HealthDay News) -- Tocilizumab (Actemra) combined with a 26-week prednisone taper is superior to either 26-week or 52-week prednisone tapering plus placebo with regard to sustained glucocorticoid-free remission in patients with giant-cell arteritis, according to a study published in the July 26 issue of the New England Journal of Medicine.

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CVD Risk Factors May Be Altered in Transgender Adults

THURSDAY, July 27, 2017 (HealthDay News) -- Cardiovascular disease (CVD) risk factors may be altered among transgender adults receiving cross-sex hormone therapy (CSHT), according to a review published online July 25 in the Annals of Internal Medicine.

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ACOG Issues Guidelines for Teen Contraception Counseling

THURSDAY, July 27, 2017 (HealthDay News) -- Recommendations for counseling adolescents about contraception are presented in a committee opinion published in the August issue of Obstetrics & Gynecology.

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SAMHSA: Opioid Abuse Up Among Older Adults

WEDNESDAY, July 26, 2017 (HealthDay News) -- While opioid abuse has decreased among younger Americans, the same cannot be said for older adults, according to the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA).

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Memantine Linked to Lower Neuron-Specific Enolase in TBI

WEDNESDAY, July 26, 2017 (HealthDay News) -- For patients with moderate traumatic brain injury (TBI), memantine is associated with reduced neuronal damage, as assessed by serum levels of neuron-specific enolase (NSE), according to a study published online July 19 in the Journal of Clinical Pharmacology.

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Case Highlights Polygenic Risk in Severe Hypertriglyceridemia

WEDNESDAY, July 26, 2017 (HealthDay News) -- Polygenic risk can mimic major monogenic mutation in severe hypertriglyceridemia, according to a case report published online July 25 in the Annals of Internal Medicine.

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Infection Is Most Common Complication of Prostate Biopsy

WEDNESDAY, July 26, 2017 (HealthDay News) -- The most common complication of prostate biopsy is infection, with mild bleeding also reported, according to an update of the American Urological Association White Paper published in the August issue of The Journal of Urology.

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Survey Reveals Prediabetes Knowledge Gaps in Primary Care

TUESDAY, July 25, 2017 (HealthDay News) -- Most primary care physicians (PCPs) can't identify all 11 risk factors for prediabetes, according to a study published online July 20 in the Journal of General Internal Medicine.

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ADHD Rx Associated With a Lower Risk for Alcohol, Drug Abuse

TUESDAY, July 25, 2017 (HealthDay News) -- Teens and adults with attention-deficit/hyperactivity disorder (ADHD) may have a lower risk of developing an alcohol or drug problem if they take medications to treat their ADHD, according to a study published online recently in the American Journal of Psychiatry.

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Continuing Statin After Adverse Rx Tied to Lower Cardiac Risk

TUESDAY, July 25, 2017 (HealthDay News) -- For patients with an adverse reaction to a statin, continued statin prescriptions are associated with lower incidence of cardiovascular events and death, according to a study published online July 25 in the Annals of Internal Medicine.

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Fasting Plasma Glucose, HbA1c Linked to Alzheimer's in T2DM

TUESDAY, July 25, 2017 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), fasting plasma glucose (FPG) visit-to-visit variation, represented by the coefficient of variation (CV), and hemoglobin A1c (HbA1c) CV are independently associated with Alzheimer's disease (AD), according to a study published online July 13 in Diabetes Care.

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Health, Economic Costs High for Measles Vaccine Hesitancy

MONDAY, July 24, 2017 (HealthDay News) -- Even small declines in vaccine coverage can reduce the herd immunity effect, according to a study published online July 24 in JAMA Pediatrics.

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Provider-, Site-Level Factors Linked to Testosterone Receipt

MONDAY, July 24, 2017 (HealthDay News) -- Provider- and site-level factors, including experience, specialty, and site location, are associated with testosterone prescribing, according to a study published online July 18 in the Journal of Clinical Endocrinology and Metabolism.

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High-Dose Flu Vaccine Cuts Admissions From Nursing Homes

MONDAY, July 24, 2017 (HealthDay News) -- High-dose influenza vaccination can reduce risk of respiratory-related hospitalization among nursing home residents aged 65 years and older, according to a study published online July 21 in The Lancet Respiratory Medicine.

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MYCN Copy Number Tied to Poor Features in Neuroblastoma

MONDAY, July 24, 2017 (HealthDay News) -- The rate of unfavorable features is increased in association with increasing MYCN copy number in patients with neuroblastoma, according to a study published online July 11 in Cancer.

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AMA Module Offers Help for Adding Pharmacist to Practice

FRIDAY, July 21, 2017 (HealthDay News) -- A new American Medical Association (AMA) education module has been developed to help embed clinical pharmacists within a medical practice.

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Few Patients Receive Rx for Smoking Cessation Meds After MI

FRIDAY, July 21, 2017 (HealthDay News) -- Among older patients in community practice, the use of smoking cessation medications (SCMs) is low after myocardial infarction (MI), according to a study published online July 19 in JAMA Cardiology.

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NCI-Designated Care Often Excluded in Narrow Health Plans

THURSDAY, July 20, 2017 (HealthDay News) -- Narrow network health plans are less likely to cover treatment by doctors at centers affiliated with the U.S. National Cancer Institute, according to a study published online July 5 in the Journal of Clinical Oncology.

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Antidepressants in Pregnancy May Contribute to Autism in Child

THURSDAY, July 20, 2017 (HealthDay News) -- In the long-standing debate over whether antidepressants are safe to take during pregnancy, a new study, published online July 19 in The BMJ, suggests that exposure to the drugs in the womb might increase a child's risk of autism.

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More Patients Enrolled in Cancer Trials Under ACA

THURSDAY, July 20, 2017 (HealthDay News) -- The Affordable Care Act may have enabled more privately insured patients to enroll in clinical trials for cancer treatments, according to a study published online July 20 in Clinical Cancer Research.

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Improved Survival With Enhanced Prophylaxis Plus ART in HIV

THURSDAY, July 20, 2017 (HealthDay News) -- For patients with advanced HIV who are initiating antiretroviral therapy (ART), enhanced antimicrobial prophylaxis is associated with reduced rates of death at 24 and 48 weeks, according to a study published in the July 20 issue of the New England Journal of Medicine.

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ASCO Addresses Cancer Drug Pricing

THURSDAY, July 20, 2017 (HealthDay News) -- Noting that new cancer drugs routinely cost more than $100,000 per year, and prices on many existing treatments continue to rise, the American Society of Clinical Oncology (ASCO) has issued a position statement to address these financial concerns.

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Capsaicin Nasal Spray Effective for Mixed Rhinitis Patients

THURSDAY, July 20, 2017 (HealthDay News) -- Capsaicin nasal spray is effective for mixed rhinitis (MR) patients, who have more than one major etiologic factor involved in the mucosal pathology, according to a study published online July 16 in Allergy.

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Aspirin Responsiveness Can Change After Bariatric Surgery

THURSDAY, July 20, 2017 (HealthDay News) -- The effects of aspirin on platelet inhibition may be more potent after bariatric surgery, according to a study published online July 14 in Cardiovascular Therapeutics.

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Animal Study Reveals Potential of Fetal Alcohol Damage Reversal

WEDNESDAY, July 19, 2017 (HealthDay News) -- Animal research may have yielded a potential treatment for fetal alcohol spectrum disorder in children; the new report was published online July 18 in Molecular Psychiatry.

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CDC: >100 Million Americans Have Diabetes or Prediabetes

WEDNESDAY, July 19, 2017 (HealthDay News) -- As of 2015, 9.4 percent of the population -- 30.3 million -- had diabetes, and another 84.1 million had prediabetes, the U.S. Centers for Disease Control and Prevention reported Tuesday.

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Reduction of Opioid Dose May Improve Pain, Quality of Life

WEDNESDAY, July 19, 2017 (HealthDay News) -- Reductions in opioid dosing might improve pain and function, as well as boost quality of life, according to a report published online July 18 in the Annals of Internal Medicine.

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Post-Op Pain May Often Be Underrated by Inpatient Staff

WEDNESDAY, July 19, 2017 (HealthDay News) -- Postoperative pain is frequently underrated when assessed by nursing staff on wards, according to a study published online July 14 in PAIN Practice.

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Survival Feasible Post Acute Liver Failure Secondary to Amiodarone

WEDNESDAY, July 19, 2017 (HealthDay News) -- In a report published online July 16 in the Journal of Clinical Pharmacy and Therapeutics, a case of survival after acute liver failure secondary to amiodarone administration is described.

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High-Dose Vitamin D No Help for Winter URIs in Children

WEDNESDAY, July 19, 2017 (HealthDay News) -- High doses of vitamin D don't protect children from upper respiratory tract infections in the winter, according to a study published in the July 18 issue of the Journal of the American Medical Association.

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Single-Dose PCV13 Immunogenic, Safe in Pediatric Oncology

WEDNESDAY, July 19, 2017 (HealthDay News) -- For pediatric and adolescent oncology patients, a single-dose 13-valent pneumococcal conjugate vaccine (PCV13) is safe and immunogenic, according to a study published online July 11 in Cancer.

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Electronic Messaging Intervention Cuts Cardiovascular Risk in T2DM

WEDNESDAY, July 19, 2017 (HealthDay News) -- For patients with type 2 diabetes mellitus, a electronic messaging intervention is effective for reducing cardiovascular risk, according to a study published online July 12 in the Journal of Clinical Nursing.

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FDA Approves Nerlynx to Help Prevent HER2+ Breast CA Return

TUESDAY, July 18, 2017 (HealthDay News) -- Nerlynx (neratinib) has been approved by the U.S. Food and Drug Administration to help prevent human epidermal growth factor receptor type 2 (HER2)-positive breast cancer from returning.

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Hospitalists Have Role to Play in Mitigating Opioid Use Disorder

TUESDAY, July 18, 2017 (HealthDay News) -- Hospitalists have an important role to play in mitigating opioid use disorder (OUD), according to an article published online July 18 in the Annals of Internal Medicine.

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Parents May Be Unclear on Teens' Vaccination Needs

MONDAY, July 17, 2017 (HealthDay News) -- New research from C.S. Mott Children's Hospital suggests that many American teens may not be getting recommended vaccinations because their parents are unaware of the need for them.

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Maternal Uncontrolled Asthma Ups Risk of Asthma in Offspring

MONDAY, July 17, 2017 (HealthDay News) -- Children whose mothers have uncontrolled asthma during pregnancy are at increased risk of developing the disease at a young age, according to a study published online July 13 in the Journal of Allergy and Clinical Immunology.

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Stem Cell Educator Therapy May Help Fight Diabetes

MONDAY, July 17, 2017 (HealthDay News) -- Stem cell educator therapy may provide long term benefits in type 1 and type 2 diabetes, according to a study published online July 7 in Stem Cells Translational Medicine.

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Opioids Often Overprescribed in Patients Undergoing Surgery

MONDAY, July 17, 2017 (HealthDay News) -- For patients undergoing common elective procedures, opioids are often overprescribed, according to a study published online July 10 in the Annals of Surgery.

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Organizational Changes Encouraged for Safer Prescribing

MONDAY, July 17, 2017 (HealthDay News) -- Organizational changes are recommended by primary care physicians to support safer prescribing, according to a study published in the July/August issue of the Annals of Family Medicine.

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Worse Outcomes for HIV Kidney Recipients on PI-Based ART

FRIDAY, July 14, 2017 (HealthDay News) -- For HIV-positive kidney transplantation (KT) recipients, outcomes are worse for those on a protease inhibitor (PI)-based versus non-PI-based antiretroviral therapy (ART) regimen, according to a study published online July 11 in the American Journal of Transplantation.

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After Sunburn, High-Dose Vitamin D Cuts Inflammatory Mediators

FRIDAY, July 14, 2017 (HealthDay News) -- Healthy adults receiving high-dose vitamin D3 have reduced expression of pro-inflammatory mediators 48 hours after experimental sunburn, according to a study published online July 5 in the Journal of Investigative Dermatology.

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Bismuth-Based Quad Tx Doesn't Top Levofloxacin Triple Tx

FRIDAY, July 14, 2017 (HealthDay News) -- For patients with Helicobacter pylori infection, the addition of bismuth subcitrate to levofloxacin-based triple therapy is not associated with increased effectiveness, although there are no more side effects, according to a study published online June 23 in the Journal of Digestive Diseases.

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Meds + Risk Factors Contribute to QTc Interval Lengthening

FRIDAY, July 14, 2017 (HealthDay News) -- In combination with risk factors, QTc interval-prolonging medications (QTPMs) are associated with greater QTc lengthening than QTPMs alone, according to a study published online July 10 in the Journal of Evaluation in Clinical Practice.

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Resistance Training Improves Microvascular Blood Flow in T2DM

FRIDAY, July 14, 2017 (HealthDay News) -- Resistance training is associated with improvement in oral glucose challenge (OGC)-stimulated muscle microvascular blood flow (MBF) and glycemic control, according to a study published online July 7 in Diabetes Care.

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Early Career Burnout Can Be Contagious Via Social Networks

FRIDAY, July 14, 2017 (HealthDay News) -- For early career teachers (ECTs), social network members' burnout levels are associated with increased burnout levels, according to a study published in the August issue of Teaching and Teacher Education.

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Opioids Second Only to Marijuana in Illicit Drug Abuse Rates

THURSDAY, July 13, 2017 (HealthDay News) -- Abuse of prescription opioids is second only to marijuana abuse as the most common illegal drug problem in the United States, according to a report from the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA).

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Errors in Opioid Prescribing for Adult Outpatients Common

THURSDAY, July 13, 2017 (HealthDay News) -- For adults receiving opioid medication prescriptions, errors are common, and most often occur on handwritten prescriptions, according to research published recently in the Journal of Opioid Management.

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New Vaccines Show Promise in Protecting Fetus From Zika

THURSDAY, July 13, 2017 (HealthDay News) -- Two experimental vaccines might help protect human fetuses against the Zika virus, according to a study published in the July 13 issue of Cell.

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Alendronate Cuts Hip Fx Risk in Seniors Taking Prednisolone

THURSDAY, July 13, 2017 (HealthDay News) -- For older patients receiving prednisolone, alendronate is associated with reduced risk of hip fracture, according to a study published in the July 11 issue of the Journal of the American Medical Association.

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Link for Maternal Antidepressant, Kids' Brain Health Questioned

THURSDAY, July 13, 2017 (HealthDay News) -- There is an increased risk of intellectual disability in children whose mothers take antidepressants while pregnant, but the association appears to be related to factors other than the medication use itself, according to a study published online July 12 in JAMA Psychiatry.

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Booster Allergen Immunotx Cuts Symptoms in Allergic Rhinitis

THURSDAY, July 13, 2017 (HealthDay News) -- For patients with grass pollen-induced allergic rhinitis (AR), booster allergen immunotherapy (AIT) using tyrosine-absorbed grass pollen allergoids containing the adjuvant monophosphoryl lipid A (MPL) prevents symptom recurrence, according to a study published online July 4 in Allergy.

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Too Many Children Not Getting Epinephrine When Needed

WEDNESDAY, July 12, 2017 (HealthDay News) -- Epinephrine administration in children at risk of anaphylaxis often occurs with considerable delay, according to a study published online July 12 in the Annals of Allergy, Asthma & Immunology.

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Rivaroxaban OK for Stroke Prevention in Cancer Patients

WEDNESDAY, June 12, 2017 (HealthDay News) -- The safety and efficacy of rivaroxaban treatment for nonvalvular atrial fibrillation (AF) in patients with active cancer is similar to the general population, according to a study published in the July 15 issue of the American Journal of Cardiology.

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Medicaid Enrollees Are Satisfied With Their Health Care

WEDNESDAY, July 12, 2017 (HealthDay News) -- Medicaid enrollees are largely satisfied with their health care, and most are able to access the care they need when they need it, according to a research letter published online July 10 in JAMA Internal Medicine.

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Addition of Aripiprazole Ups Major Depressive Disorder Remission

WEDNESDAY, July 12, 2017 (HealthDay News) -- For patients with major depressive disorder (MDD), augmentation with aripiprazole is associated with an increased likelihood of remission, according to a study published in the July 11 issue of the Journal of the American Medical Association.

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More Than 1 in 3 With Behçet's Has Bacterial Overgrowth

WEDNESDAY, July 12, 2017 (HealthDay News) -- About one-third of patients with inactive intestinal Behçet's disease (BD) have small intestinal bacterial overgrowth (SIBO), and rifaximin is associated with symptom improvement, according to a study published online June 30 in the Journal of Gastroenterology and Hepatology.

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Increased Parental Anxiety With Increased Diabetes Risk

WEDNESDAY, July 12, 2017 (HealthDay News) -- Parents of children at increased genetic risk for type 1 diabetes and with positive islet autoantibody (IA) testing have increased anxiety, according to a study published online June 29 in Diabetes Care.

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Review: Little Evidence on Vitamin D-Allergy Association

WEDNESDAY, July 12, 2017 (HealthDay News) -- Vitamin D supplementation seems not to prevent allergies in pregnant women, breastfeeding women, or infants, though there is very little evidence about the association between vitamin D and allergic diseases, according to a review published online July 4 in Allergy.

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Sildenafil-Coated Stent May Help Prevent Clots, Stenosis

TUESDAY, July 11, 2017 (HealthDay News) -- Sildenafil-coated stents appear to cut a patient's odds for clots, according to an experimental study presented at the American Heart Association's Basic Cardiovascular Sciences 2017 Scientific Sessions, held from July 10 to 13 in Portland, Ore.

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Cognitive Screening Tools Can Be Used in Home Medication Review

TUESDAY, July 11, 2017 (HealthDay News) -- Suitable cognitive screening tools can be used by pharmacists during home medication review, according to research published online July 5 in the Journal of Pharmacy Practice and Research.

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Reduced Rates of Gonorrhea Seen With Meningococcal B Vaccine

TUESDAY, July 11, 2017 (HealthDay News) -- A vaccine for gonorrhea may be one step closer to reality, according to a report published online July 10 in The Lancet.

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Health Service Use Unchanged From 1996-1997 to 2011-2012

TUESDAY, July 11, 2017 (HealthDay News) -- Utilization of health services was largely unchanged from 1996-1997 to 2011-2012, but expenditures increased, according to a study published in the July/August issue of the Annals of Family Medicine.

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American Adults Without Health Insurance Rises by Two Million

TUESDAY, July 11, 2017 (HealthDay News) -- The number of American adults without health insurance has increased by about two million so far this year, according to a new Gallup-Sharecare Well-Being Index poll.

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Rate of Non-Health Care Facility Medication Errors on the Rise

MONDAY, July 10, 2017 (HealthDay News) -- The rate of serious medication errors has doubled since 2000, according to a study published online July 10 in Clinical Toxicology.

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FDA Approves Endari for the Treatment of Sickle Cell Disease

MONDAY, July 10, 2017 (HealthDay News) -- The U.S. Food and Drug Administration has approved Endari (L-glutamine oral powder) to treat patients with sickle cell disease.

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No Signs of Abuse Potential for Eluxadoline in IBS With Diarrhea

MONDAY, July 10, 2017 (HealthDay News) -- For patients with irritable bowel syndrome with diarrhea (IBS-D), there are no signs of abuse potential for eluxadoline, according to a study published in the July issue of Clinical Gastroenterology and Hepatology.

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Allergists Concerned About Bee, Wasp Venom Extract Shortage

FRIDAY, July 7, 2017 (HealthDay News) -- A shortage of honeybee, wasp, and hornet venom extract has allergists concerned.

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AAAAI/ACAAI Joint Venom Extract Shortage Task Force Report

Over Half of Opioids Prescribed to Adults With Mental Illness

FRIDAY, July 7, 2017 (HealthDay News) -- Of the 115 million prescriptions written for opioids each year in the United States, 60 million are for adults with mental illness, according to a study published online July 6 in the Journal of the American Board of Family Medicine.

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New Opioid Use in Older Adults With COPD May Up Cardiac Events

FRIDAY, July 7, 2017 (HealthDay News) -- Adverse cardiac events may need to be considered with new opioid use in older adults with chronic obstructive pulmonary disease (COPD), according to a study published online June 29 in the European Journal of Clinical Pharmacology.

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Nephrotic Syndrome Reported With Everolimus, Voriconazole

FRIDAY, July 7, 2017 (HealthDay News) -- In a case report published online June 29 in the Journal of Clinical Pharmacy and Therapeutics, nephrotic syndrome is diagnosed in a 32-year-old female with relapsed Hodgkin's lymphoma who was on everolimus and initiated voriconazole.

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Improved Glycemic Control With Eradication of Hepatitis C

FRIDAY, July 7, 2017 (HealthDay News) -- For patients with type 2 diabetes, direct-acting antiviral (DAA) treatment of hepatitis C virus (HCV) is associated with improved glycemic control and reduced antidiabetic medication use, according to a study published online June 28 in Diabetes Care.

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Market Competition Linked to Change in Generic Drug Prices

THURSDAY, July 6, 2017 (HealthDay News) -- Market competition levels are associated with changes in the price of generic drugs, according to a study published online July 4 in the Annals of Internal Medicine.

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Insulin Degludec Linked to Reduced Rate of Hypoglycemia

THURSDAY, July 6, 2017 (HealthDay News) -- For patients with type 1 or type 2 diabetes, insulin degludec is associated with a reduced rate of hypoglycemic episodes compared with insulin glargine, according to two studies published in the July 4 issue of the Journal of the American Medical Association.

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From 2001 to 2012, Incidence of CDI, Multiply Recurrent CDI Up

THURSDAY, July 6, 2017 (HealthDay News) -- The annual incidence of Clostridium difficile infection (CDI) and multiply recurrent CDI (mrCDI) increased from 2001 to 2012, according to a study published online July 4 in the Annals of Internal Medicine.

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FDA Expands Use of Cooling Cap to Cut Chemo-Related Hair Loss

WEDNESDAY, July 5, 2017 (HealthDay News) -- A cooling cap approved in 2015 for use in breast cancer patients has received expanded approval from the U.S. Food and Drug Administration.

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At-Risk Pain Patients Can Cut Opioid Use With Psychology Tools

WEDNESDAY, July 5, 2017 (HealthDay News) -- Teaching coping skills may help reduce the risk that patients with chronic pain will become addicted to opioids, according to research published online June 28 in the Canadian Journal of Pain.

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No Evidence Probiotics Protect Infants Against Infections

WEDNESDAY, July 5, 2017 (HealthDay News) -- Probiotic supplements do not appear to lower infants' risk of infection in day care, according to research published online July 3 in Pediatrics.

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Proton Pump Inhibitors Linked to Higher Mortality Risk

WEDNESDAY, July 5, 2017 (HealthDay News) -- Proton pump inhibitors (PPIs) may increase risk of premature mortality when taken for extended periods, according to research published online July 4 in BMJ Open.

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Many Children With Reported Penicillin Allergy Are Not Allergic

WEDNESDAY, July 5, 2017 (HealthDay News) -- Many children suspected of being allergic to penicillin actually aren't, according to a study published online July 3 in Pediatrics.

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Use of Palliative Care Up for End-Stage Liver Disease

WEDNESDAY, July 5, 2017 (HealthDay News) -- For patients with end-stage liver disease (ESLD), the use of palliative care (PC) increased from 2006 to 2012, according to research published online June 29 in Hepatology.

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Many U.S. Teens Can't Access Emergency Contraception

WEDNESDAY, July 5, 2017 (HealthDay News) -- Although the U.S. Food and Drug Administration has lifted age restrictions on the use of levonorgestrel emergency contraception (EC), many teens may still have difficulty obtaining the medication, according to a study published online June 30 in Pediatrics.

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Therapeutic Inertia in 19 Percent With T2DM, HbA1c ≥8 Percent

WEDNESDAY, July 5, 2017 (HealthDay News) -- Therapeutic inertia occurs in 19.1 percent of patients with type 2 diabetes with hemoglobin A1c (HbA1c) ≥8 percent on two or more non-insulin antidiabetic drugs (NIADs), according to a study published online June 28 in Diabetes, Obesity and Metabolism.

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