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December 2017 Briefing - Nephrology

Last Updated: January 02, 2018.

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for December 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Out-of-Pocket Costs Correlate With Receipt of Cancer Care

THURSDAY, Dec. 28, 2017 (HealthDay News) -- Across cancers, higher out-of-pocket (OOP) costs are associated with higher rates of oral prescription abandonment and delayed initiation, according to a study published online Dec. 20 in the Journal of Clinical Oncology.

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Risk of ESRD in T1DM Patients Has Fallen Markedly in Finland

WEDNESDAY, Dec. 27, 2017 (HealthDay News) -- The cumulative risk of end-stage renal disease (ESRD) among patients with type 1 diabetes has declined over time in Finland, according to a study published online Dec. 20 in Diabetes Care.

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Rituximab Effective for Lupus-Associated Cytopenia

WEDNESDAY, Dec. 27, 2017 (HealthDay News) -- Rituximab treatment seems effective for systemic lupus erythematosus (SLE)-associated immune cytopenias, with an overall initial response rate of 86 percent, according to a study published online Dec. 16 in the American Journal of Hematology.

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Early-Stage Cancer Diagnoses Up With ACA's Medicaid Expansions

THURSDAY, Dec. 21, 2017 (HealthDay News) -- In their first year, the 2014 Medicaid expansions, facilitated by the Affordable Care Act, were associated with an increase in cancer diagnoses, particularly at the early stage, according to a study published online Dec. 21 in the American Journal of Public Health.

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CDC: 2015 to 2016 Saw Drop in Life Expectancy in United States

THURSDAY, Dec. 21, 2017 (HealthDay News) -- From 2015 to 2016, life expectancy decreased by one-tenth of a year, and there was an increase in the rate of age-adjusted drug overdose deaths, according to two December data briefs published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Male U.S. Doctors Receive Higher Values of Industry Payments

MONDAY, Dec. 18, 2017 (HealthDay News) -- Male physicians in the United States received higher values of general payments from industry than females in 2015, according to a research letter published online Dec. 18 in JAMA Internal Medicine.

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Emergency-Only Hemodialysis Linked to Worse Outcomes

MONDAY, Dec. 18, 2017 (HealthDay News) -- Emergency-only hemodialysis treatment is associated with increased mortality compared with standard hemodialysis for undocumented immigrants with end-stage renal disease, according to a study published online Dec. 18 in JAMA Internal Medicine.

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Equation Predicts Risk of End-Stage Renal Disease in Children

MONDAY, Dec. 18, 2017 (HealthDay News) -- The kidney failure risk equation (KFRE) is a simple tool that provides excellent discrimination of the risk of end-stage renal disease (ESRD) in children with chronic kidney disease (CKD), according to a study published online Dec. 18 in JAMA Pediatrics.

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Year One Results Out for Value-Based Payment Modifier Program

MONDAY, Dec. 18, 2017 (HealthDay News) -- Almost 30 percent of eligible practices failed to register and report data in the first year of the Physician Value-Based Payment Modifier program, according to a report published in the December issue of Health Affairs.

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Doctors Must Report on at Least 1 Patient, 1 Measure for MACRA

FRIDAY, Dec. 15, 2017 (HealthDay News) -- In order to meet the 2017 Medicare and CHIP Reauthorization Act (MACRA) participation reporting deadline and avoid a Medicare payment penalty in 2019, physicians must report on at least one patient and one measure by Dec. 31, and submit to Medicare no later than Feb. 28, 2018, according to a report from the American Medical Association (AMA).

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Recent Decrease in Excess Risk of All-Cause Mortality in ESRD

FRIDAY, Dec. 15, 2017 (HealthDay News) -- Among individuals with end-stage renal disease (ESRD), there was a decrease in the excess risk of all-cause mortality from 1995 to 2013, according to a study published online Dec. 14 in the Clinical Journal of the American Society of Nephrology.

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Expanded TIMI Risk Score Deemed Practical in Diabetes

FRIDAY, Dec. 15, 2017 (HealthDay News) -- The TIMI (Thrombolysis in Myocardial Infarction) Risk Score for Secondary Prevention (TRS 2°P) is an accurate predictor of atherothrombotic disease among patients with type 2 diabetes, according to a study published online Dec. 1 in Diabetes Care.

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Prevalence of Diabetes Tops 20 Percent Among U.S. Veterans

THURSDAY, Dec. 14, 2017 (HealthDay News) -- The overall prevalence of diabetes among U.S. veterans was 20.5 percent in 2013 to 2014, according to a study published online Dec. 14 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Making Insurers Participate in Marketplace Could Cut Volatility

THURSDAY, Dec. 14, 2017 (HealthDay News) -- Requiring insurers that participate in Medicare or Medicaid to also participate in Marketplaces in the same geographic area could improve access to insurance, according to a study published in the December issue of Health Affairs.

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Recent Change in Spectrum of HIV-Linked Kidney Disease

THURSDAY, Dec. 14, 2017 (HealthDay News) -- The spectrum of HIV-associated kidney disease has changed with the improvement of therapy for HIV infection, according to a review article published in the Dec. 14 issue of the New England Journal of Medicine.

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Findings Could Help Reduce Risk of Calciphylaxis in Renal Disease

WEDNESDAY, Dec. 13, 2017 (HealthDay News) -- For patients with late-stage renal disease, the presence of lupus anticoagulant and combined thrombophilias are risk factors for the development of calciphylaxis, according to a study published online Dec. 13 in JAMA Dermatology.

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Measuring Quality of Life Important With Diabetes Tx

WEDNESDAY, Dec. 13, 2017 (HealthDay News) -- Patients with diabetes report worse quality of life (QoL) with more intensified treatment, according to a study published in online Nov. 28 in Diabetes Care.

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C. Difficile + Kidney Injury Admissions Are Up

WEDNESDAY, Dec. 13, 2017 (HealthDay News) -- Hospital admissions of patients with Clostridium difficile infection (CDI) and accompanying acute kidney injury (AKI) are increasing, according to a study published online Dec. 4 in the Journal of Gastroenterology and Hepatology.

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Deceleration in Health Care Spending Growth in 2016

MONDAY, Dec. 11, 2017 (HealthDay News) -- Health care spending growth slowed in 2016 following faster growth in 2014 and 2015, according to research published online Dec. 6 in Health Affairs.

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CVS-Aetna Merger Has Implications for Doctors' Offices

TUESDAY, Dec. 5, 2017 (HealthDay News) -- CVS Health's planned purchase of insurance giant Aetna, a $69 billion deal, was announced Sunday.

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Diagnostic Mutations ID'd in Chronic Kidney Disease Patients

TUESDAY, Dec. 5, 2017 (HealthDay News) -- About one-quarter of adults with chronic kidney disease (CKD) of unknown cause or familial nephropathy or hypertension have diagnostic mutations, which can be identified with whole-exome sequencing (WES), according to a study published online Dec. 5 in the Annals of Internal Medicine.

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Ceruloplasmin ID'd As Marker of Kidney Disease in Sickle Cell

MONDAY, Dec. 4, 2017 (HealthDay News) -- In patients with sickle cell anemia (SCA), urinary ceruloplasmin (CP) may complement urinary free hemoglobin as a noninvasive biomarker for chronic kidney disease (CKD), according to research published online Nov. 27 in the American Journal of Hematology.

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Targeting Ups Nanoparticle Delivery to Graft Endothelial Cells

FRIDAY, Dec. 1, 2017 (HealthDay News) -- Targeting can enhance accumulation of nanoparticles (NPs) to graft endothelial cells (ECs) of human kidneys undergoing ex vivo normothermic machine perfusion (NMP), according to research published online Nov. 29 in Science Translational Medicine.

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Almonds With/Without Chocolate May Improve Lipid Profiles

FRIDAY, Dec. 1, 2017 (HealthDay News) -- Eating raw almonds, dark chocolate, and cocoa can significantly improve lipid profiles of overweight and obese people, according to a small study published online Nov. 29 in the Journal of the American Heart Association.

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>40% of Cancers, Cancer Deaths Due to Modifiable Risk Factors

FRIDAY, Dec. 1, 2017 (HealthDay News) -- An estimated 42.0 percent of all incident cancers and 45.1 percent of cancer deaths in the United States are attributed to potentially modifiable risk factors, according to a study published online Nov. 21 in CA: A Cancer Journal for Clinicians.

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