Search Finds Higher Pediatric Ischemic Stroke RateLast Updated: September 18, 2009. Using radiology searches results in a substantially higher estimate of the incidence of pediatric ischemic stroke than previous estimates, according to research published online Sept. 17 in Stroke.
FRIDAY, Sept. 18 (HealthDay News) -- Using radiology searches results in a substantially higher estimate of the incidence of pediatric ischemic stroke than previous estimates, according to research published online Sept. 17 in Stroke.
Nidhi Agrawal, M.D., of the University of California in San Francisco, and colleagues analyzed data from children and teens enrolled in the Kaiser Permanente Medical Care Program between 1993 and 2003. The authors used International Classification of Diseases, 9th Revision (ICD-9) code searches and text string searches in head imaging reports for case identification.
The authors found 205 confirmed cases of ischemic stroke (45 through ICD-9 alone and 118 through radiology search alone). Both searches had low positive predictive values, but the radiology search had higher sensitivity (83 versus 39 percent). The ischemic stroke incidence was 2.4 per 100,000 person-years, compared to previous annualized incidence estimates of 0.54 to 1.2 ischemic strokes per 100,000 children.
"Our study is the first to use two search strategies to estimate the incidence of pediatric ischemic stroke in the United States and found a rate two to four times higher than prior reports. Although radiology searches appear to have a greater sensitivity for pediatric stroke, both search strategies have relatively low yield. These challenges in retrospective case identification support recent calls for the field to move toward prospective multicenter studies of pediatric stroke," the authors conclude.
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