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March 2019 Briefing - Pulmonology

Last Updated: April 01, 2019.

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for March 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Perception of E-Cigarettes as More Harmful Than Cigarettes Increased

FRIDAY, March 29, 2019 (HealthDay News) -- From 2012 to 2017, the proportion of U.S. adults who perceived electronic-cigarettes to be as harmful as or more harmful than cigarettes increased, according to a study published online March 29 in JAMA Network Open.

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Editorial

Dietary Fatty Acid Intake Linked to Pediatric Asthma Morbidity

FRIDAY, March 29, 2019 (HealthDay News) -- Intake of omega-3 and omega-6 is associated with pediatric asthma morbidity and may modify the response to indoor particulate matter (PM), according to a study published online March 29 in the American Journal of Respiratory and Critical Care Medicine.

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Doctors With Malpractice Claims More Likely to Leave Medicine

THURSDAY, March 28, 2019 (HealthDay News) -- Physicians with one or more paid malpractice claims are more likely to leave practice or shift into smaller practice settings, according to a study published in the March 28 issue of the New England Journal of Medicine.

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Douglas County, Colorado, Ranked as Healthiest Community

TUESDAY, March 26, 2019 (HealthDay News) -- The 2019 healthiest community in America is Douglas County, Colorado, according to a report published online March 26 by U.S. News & World Report, in conjunction with the Aetna Foundation.

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Radiomic Features May Predict Response to Chemo in NSCLC

TUESDAY, March 26, 2019 (HealthDay News) -- For patients with lung adenocarcinoma, radiomic texture features extracted from within and around the nodule on baseline computed tomography (CT) scans can predict response to chemotherapy, according to a study published online March 20 in Radiology: Artificial Intelligence.

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Blindfolding Leader Improves Pediatric Resuscitation Training

TUESDAY, March 26, 2019 (HealthDay News) -- Team leaders who wear a blindfold during pediatric resuscitation simulation-based training show improved leadership skills compared with standard training teams, according to a study recently published in Frontiers in Pediatrics.

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2019 Residency Match Day Was Largest in History

MONDAY, March 25, 2019 (HealthDay News) -- The 2019 Main Residency Match was the largest in history, with a record high of 38,376 applicants for 35,185 positions, according to 2019 Match Day results released by the National Resident Matching Program.

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Pregnancy-Adapted Algorithm Avoids Diagnostic Imaging for PE

WEDNESDAY, March 20, 2019 (HealthDay News) -- A pregnancy-adapted algorithm can safely avoid diagnostic imaging in a proportion of pregnant women with suspected pulmonary embolism, according to a study published in the March 21 issue of the New England Journal of Medicine.

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Overall, Physicians Are Happy and Enjoy Their Lives

WEDNESDAY, March 20, 2019 (HealthDay News) -- Overall, physicians are happy and enjoy their lives, according to the 2019 American Academy of Family Physicians (AAFP)/CompHealth Physician Happiness Survey published online March 19.

2019 AAFP/CompHealth Physician Happiness Survey

Patients With Diabetes at Increased Risk for Sleep Apnea

WEDNESDAY, March 20, 2019 (HealthDay News) -- Patients with type 2 diabetes are at increased risk for developing obstructive sleep apnea (OSA), independent of other factors, according to a study published online March 12 in Diabetes Care.

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Practices for Reducing COPD Hospital Readmissions Explored

WEDNESDAY, March 20, 2019 (HealthDay News) -- Communication, implementation of guidelines, and improved identification of risk factors may help reduce chronic obstructive pulmonary disease (COPD) hospital readmissions, according to a report published in the February issue of the Annals of the American Thoracic Society.

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FDA OKs Tecentriq for Extensive-Stage Small Cell Lung Cancer

TUESDAY, March 19, 2019 (HealthDay News) -- Tecentriq (atezolizumab) has been approved by the U.S. Food and Drug Administration to treat adults with extensive-stage small cell lung cancer.

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Analgesics in Pregnancy Do Not Seem to Cause Offspring Asthma

TUESDAY, March 19, 2019 (HealthDay News) -- Analgesics taken during pregnancy, including opioids, antimigraine drugs, and paracetamol, do not appear to cause asthma, according to a study published online March 17 in the European Respiratory Journal.

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Novel Checklist Can Distinguish Anthrax Exposure From Other Illnesses

TUESDAY, March 19, 2019 (HealthDay News) -- A newly developed checklist can rapidly identify anthrax cases after a suspected mass exposure, according to a study published online March 19 in the Annals of Internal Medicine.

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In Utero Ultrafine Particle Exposure Tied to Asthma in Offspring

MONDAY, March 18, 2019 (HealthDay News) -- Exposure to ultrafine particles (UFPs; <0.1 μm) during the second trimester in utero is linked to the subsequent onset of asthma in children, according to a study published online Feb. 20 in the American Journal of Respiratory and Critical Care Medicine.

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Average of 8.8 Inactive Ingredients Found in Oral Medications

MONDAY, March 18, 2019 (HealthDay News) -- Oral forms of medications contain an average of 8.8 inactive ingredients, many of which could cause adverse reactions, according to a perspective piece published in the March 13 issue of Science Translational Medicine.

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Physician Burnout Rate Increased From 2014 to 2017

FRIDAY, March 15, 2019 (HealthDay News) -- From 2014 to 2017, there was an increase in physician burnout, with early-career physicians being the most susceptible, according to a study published online March 15 in JAMA Network Open.

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E-Cigarettes May Threaten Goal of Achieving Tobacco Endgame

THURSDAY, March 14, 2019 (HealthDay News) -- There is considerable concern regarding the potential negative impact that electronic cigarettes and other new products may have on ending all tobacco use and nicotine addiction, according to a presidential advisory issued by the American Heart Association and published online March 13 in Circulation.

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Prenatal High-Dose Vitamin D Not Linked to Asthma at Age 6

THURSDAY, March 14, 2019 (HealthDay News) -- High-dose vitamin D supplementation in pregnancy is not associated with a child's risk for asthma at age 6 years, according to a research letter published in the March 12 issue of the Journal of the American Medical Association.

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New AI Model May Predict Cancerous Lung Nodules

THURSDAY, March 14, 2019 (HealthDay News) -- The Lung Cancer Causal Model (LCCM) shows promise as a predictor of cancerous lung nodules, according to a study published online March 12 in Thorax.

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One-Month Regimen Noninferior for Preventing HIV-Related TB

THURSDAY, March 14, 2019 (HealthDay News) -- For HIV-infected patients, a one-month regimen of rifapentine and isoniazid is noninferior to nine months of isoniazid alone for preventing tuberculosis, according to a study published in the March 14 issue of the New England Journal of Medicine.

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Editorial

Complex Dosing, Polypharmacy Common With Interstitial Lung Disease

THURSDAY, March 14, 2019 (HealthDay News) -- Polypharmacy and complex medication regimens are common in patients with interstitial lung disease (ILD), according to a study published online Feb. 20 in Respirology.

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Short Regimen Noninferior for Rifampin-Resistant Tuberculosis

WEDNESDAY, March 13, 2019 (HealthDay News) -- A short regimen is noninferior to a long regimen for patients with rifampin-resistant tuberculosis that is susceptible to fluoroquinolones and aminoglycosides, according to a study published online March 13 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Head of National Cancer Institute Named Acting FDA Commissioner

WEDNESDAY, March 13, 2019 (HealthDay News) -- The U.S. Food and Drug Administration will temporarily be overseen by the head of the National Cancer Institute when FDA Commissioner Scott Gottlieb, M.D., leaves the post next month.

AP News Article

Bronchiolitis Hospitalization in Infancy Predicts More Admissions

WEDNESDAY, March 13, 2019 (HealthDay News) -- More than one in five infants with a bronchiolitis hospital admission will have a subsequent respiratory-related hospital admission by age 5 years, according to a study published online March 6 in the Archives of Disease in Childhood.

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CDC: Most Americans Report Excellent, Good Health

WEDNESDAY, March 13, 2019 (HealthDay News) -- Most Americans report having excellent or good health and have a usual place to go for medical care, according to a report published March 13 for the National Health Interview Survey Early Release Program.

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Homes With High Ventilation Rates Tied to Respiratory Issues

WEDNESDAY, March 13, 2019 (HealthDay News) -- People living in homes with high average air exchange rates (AAERs) are more likely to report chronic cough, asthma, or asthma-like symptoms, according to a study published in the February issue of Environmental Research.

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Parent Perception of E-Cig Safety Varies With Smoking Habits

TUESDAY, March 12, 2019 (HealthDay News) -- Parents who both smoke cigarettes and electronic cigarettes are less likely to have smoke-free car and vape-free car or home policies compared with cigarette users, according to a study published online March 11 in Pediatrics.

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CDC: Flu Season May Have Peaked

MONDAY, March 11, 2019 (HealthDay News) -- It looks like the flu season has peaked in the United States, though there has been a recent rise in the number of cases involving a more severe flu strain.

AP News Article
More Information: CDC

Children With Poorly Controlled Asthma Suffer Academically

MONDAY, March 11, 2019 (HealthDay News) -- Urban children with asthma, particularly those who are ethnic minorities, have more school absences than their peers without asthma, according to a study published online March 11 in the Annals of Allergy, Asthma, & Immunology.

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Cardiorespiratory Fitness Tied to Coronary Heart Disease Risk

MONDAY, March 11, 2019 (HealthDay News) -- Poor cardiorespiratory fitness is strongly associated with coronary heart disease (CHD) in a low-risk population, according to a study recently published in the European Heart Journal.

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Exfoliation Syndrome May Up Risk for COPD

FRIDAY, March 8, 2019 (HealthDay News) -- Patients with exfoliation syndrome (XFS) may be at increased risk for chronic obstructive pulmonary disease (COPD), according to a study published in the January-February issue of Ophthalmology Glaucoma.

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Water Pipe Tobacco Smoking Addictive, Harmful to the Heart

FRIDAY, March 8, 2019 (HealthDay News) -- Smoking a water pipe is addictive and can increase the risk for initiating cigarette smoking, according to a scientific statement from the American Heart Association published online March 8 in Circulation.

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Predictors ID'd for Successful Removal of Mechanical Ventilation

THURSDAY, March 7, 2019 (HealthDay News) -- Mechanically ventilated patients who pass a spontaneous breathing trial (SBT) and are extubated reach a higher level of wakefulness, indicated by a higher odds ratio product (ORP), according to a study published online March 1 in the American Journal of Respiratory and Critical Care Medicine.

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FDA Commissioner Dr. Scott Gottlieb Resigns

TUESDAY, March 5, 2019 (HealthDay News) -- In what probably came as a surprise to many, U.S. Food and Drug Administration Commissioner Scott Gottlieb, M.D., announced his resignation on Tuesday. Gottlieb is leaving the FDA because he wants to spend more time with his wife and three young daughters -- twins aged 9 and a 5-year-old -- one official said. He currently commutes each week from the family home in Connecticut to his Washington, D.C., office.

The Washington Post Article

AASM Releases New Sleep Apnea Treatment Guideline

TUESDAY, March 5, 2019 (HealthDay News) -- A new guideline, published Feb. 15 in the Journal of Clinical Sleep Medicine, establishes clinical practice recommendations for positive airway pressure (PAP) treatment of obstructive sleep apnea (OSA) in adults.

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COPD, ILD Patients May Not Benefit From Bilateral Lung Transplant Listing

MONDAY, March 4, 2019 (HealthDay News) -- While an unrestricted listing strategy does not seem to impact overall survival among patients with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD) awaiting lung transplant, it may increase the number of transplants performed, according to a study published in the February issue of the Annals of the American Thoracic Society.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Readmission for Patients With Sepsis Common and Costly

MONDAY, March 4, 2019 (HealthDay News) -- Readmission after sepsis hospitalization is common and is associated with considerable costs, according to a study published in the March issue of CHEST.

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Pneumococcal Vaccination at Age 50 Prevents the Most Disease

MONDAY, March 4, 2019 (HealthDay News) -- Recommending pneumococcal vaccination for all 50-year-olds prevents the most disease in underserved minorities and the general population, but the cost exceeds $250,000 per quality-adjusted life-year (QALY) gained, according to a study published online March 4 in Vaccine.

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Electronic Decision Support Tool Can Aid Asthma Care

FRIDAY, March 1, 2019 (HealthDay News) -- A new electronic decision support tool can improve the quality of asthma care in primary care settings, according to a study published online Feb. 14 in the European Respiratory Journal.

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FDA Warns Americans Not to Buy Drugs From Canadian Company

FRIDAY, March 1, 2019 (HealthDay News) -- A large Canadian drug distributor sells unapproved and mislabeled medicines to Americans, the U.S. Food and Drug Administration warned Thursday. The distributor disputes the claim, however.

The New York Times Article
More Information: FDA


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