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Category: Pharmacy | Monthly Briefing

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August 2019 Briefing - Pharmacy

Last Updated: September 03, 2019.

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for August 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Interest in Marijuana, Cannabinoids for Pain Rising Rapidly

FRIDAY, Aug. 30, 2019 (HealthDay News) -- There is rapidly growing interest in the use of marijuana and cannabinoids for pain, according to a survey commissioned by the American Society of Anesthesiologists (ASA).

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CDC Boosts Efforts to Fight Congo Ebola Outbreak

FRIDAY, Aug. 30, 2019 (HealthDay News) -- The U.S. Centers for Disease Control and Prevention has stepped up its efforts to help fight the Ebola outbreak in the Democratic Republic of the Congo (DRC).

More Information: CDC
CBS News Article

Netarsudil Lowers IOP in Glaucoma, Ocular Hypertension

FRIDAY, Aug. 30, 2019 (HealthDay News) -- Netarsudil ophthalmic solution (0.02 percent; once daily) significantly reduced mean intraocular pressure (IOP) among patients with open-angle glaucoma or ocular hypertension, according to a study published in the August issue of the American Journal of Ophthalmology.

Abstract/Full Text

Type and Timing of Menopausal HRT Affect Risk for Breast Cancer

FRIDAY, Aug. 30, 2019 (HealthDay News) -- Use of menopausal hormone therapy (MHT) is associated with an increased incidence of breast cancer, according to a study published online Aug. 29 in The Lancet.

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Editorial

CDC: January to July 2018 Saw Decrease in Opioid Deaths

THURSDAY, Aug. 29, 2019 (HealthDay News) -- Opioid deaths decreased during January to July 2018, while deaths from illicitly manufactured fentanyl (IMF) increased during the same period, according to research published in the Aug. 30 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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FDA: Risk From Tainted Blood Pressure Drugs Very Low

THURSDAY, Aug. 29, 2019 (HealthDay News) -- The health risk from contamination of widely used generic blood pressure medications, angiotensin II receptor blockers, is very low, according to the U.S. Food and Drug Administration.

AP News Article
More Information: FDA

FDA Reports Rare Cases of Liver Injury, Failure With Hep C Therapies

THURSDAY, Aug. 29, 2019 (HealthDay News) -- The U.S. Food and Drug Administration has received reports of rare cases of worsening liver function or liver failure in patients with chronic hepatitis C virus (HCV) who had moderate-to-severe liver impairment and were treated with Mavyret, Zepatier, or Vosevi, despite these drugs being contraindicated in this group of patients, the agency reported yesterday.

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Hormone Tx Not Tied to Change in Muscle Mass in Older Women

THURSDAY, Aug. 29, 2019 (HealthDay News) -- Hormone therapy (HT) does not significantly impact muscle mass in postmenopausal women, according to a review published online Aug. 28 in JAMA Network Open.

Abstract/Full Text

New Anti-CRE Antibiotics Used for 35 Percent of Infections

THURSDAY, Aug. 29, 2019 (HealthDay News) -- Currently, new anti-carbapenem-resistant Enterobacteriaceae (CRE) antibiotics are estimated to treat 35 percent of CRE infections in which they were expected to be used as first-line agents, according to a study published in the August issue of Open Forum Infectious Diseases.

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Guidelines Updated for Vaccination in Multiple Sclerosis

WEDNESDAY, Aug. 28, 2019 (HealthDay News) -- Guidelines have been updated on vaccinations in patients with multiple sclerosis (MS); a practice guideline update summary was published online Aug. 28 in Neurology.

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Vaccine-Related Searches on Pinterest Will Show Only Public Health Organizations

WEDNESDAY, Aug. 28, 2019 (HealthDay News) -- From now on, vaccine-related searches on Pinterest will only produce results from public health organizations.

CNN Article

Treatment Guidelines Updated for Ankylosing Spondylitis, Axial SpA

WEDNESDAY, Aug. 28, 2019 (HealthDay News) -- In a special article published online Aug. 21 in Arthritis Care & Research, the American College of Rheumatology, Spondylitis Association of America, and Spondyloarthritis Research and Treatment Network present updated recommendations for the treatment of ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA).

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Dipeptidyl Peptidase-4 Inhibitors May Up Pancreatic Disease Risk

WEDNESDAY, Aug. 28, 2019 (HealthDay News) -- Use of dipeptidyl peptidase-4 inhibitors (DPP-4i) is associated with increased risks for pancreatitis and pancreatic cancer in patients with newly diagnosed type 2 diabetes, according to a study published online Aug. 20 in Diabetes Care.

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Salvage Therapy Does Not Up Survival for Progressive Myeloma

WEDNESDAY, Aug. 28, 2019 (HealthDay News) -- For myeloma patients with progressive disease (PD) after induction therapy, deepening of response through salvage therapy is not associated with improved progression-free or overall survival, according to a study published online Aug. 19 in Leukemia & Lymphoma.

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DEA to Approve Dozens More Growers for Marijuana Research

TUESDAY, Aug. 27, 2019 (HealthDay News) -- The number of marijuana growers allowed to produce the drug for U.S. government-approved research will be expanded from one to 34, officials say.

AP News Article

OxyContin Maker Offers Up to $12 Billion to Settle Opioid Claims

TUESDAY, Aug. 27, 2019 (HealthDay News) -- Purdue Pharma, the drug giant many have blamed for the ongoing U.S. opioid abuse crisis, has offered $10 billion to $12 billion to settle more than 2,000 lawsuits lodged against it, NBC News is reporting.

NBC News Article

Combo Tx May Improve Disease Control for Some in Early RA

TUESDAY, Aug. 27, 2019 (HealthDay News) -- For patients with early rheumatoid arthritis (RA) and high disease activity, the combination of a tumor necrosis factor (TNF) or non-TNF biologic with methotrexate improves disease control, remission, and functional capacity compared with monotherapy, according to a review published online Aug. 6 in the Journal of General Internal Medicine.

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Prices Spike for Drugs Used to Treat Multiple Sclerosis

TUESDAY, Aug. 27, 2019 (HealthDay News) -- From 2006 to 2016, the prices of self-administered disease-modifying therapies (DMTs) for multiple sclerosis increased, according to a study published online Aug. 26 in JAMA Neurology.

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Editorial (subscription or payment may be required)

Polyunsaturated Fatty Acids Have Little, No Impact on Diabetes

TUESDAY, Aug. 27, 2019 (HealthDay News) -- Polyunsaturated fatty acids (PUFA) have little to no effect on the prevention or treatment of type 2 diabetes mellitus, according to a review published online Aug. 21 in The BMJ.

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Prenatal Exposure to OMT Does Not Worsen Neonatal Outcomes

TUESDAY, Aug. 27, 2019 (HealthDay News) -- Exposure to opioid maintenance treatment (OMT) in the womb does not seem to cause additional harm to newborns, according to a study published online Aug. 14 in Pharmacology Research & Perspectives.

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Oklahoma Judge Fines Johnson & Johnson $572 Million Over Opioid Drug Crisis

MONDAY, Aug. 26, 2019 (HealthDay News) -- An Oklahoma judge on Monday ruled against one of America's biggest companies, Johnson & Johnson -- fining it $572 million as part of the first trial of an opioid maker sued by a state for the human and financial costs of the prescription painkiller crisis.

The New York Times Article

Tourist With Measles Visited Southern California Attractions

MONDAY, Aug. 26, 2019 (HealthDay News) -- People who were at Disneyland and other Southern California tourist attractions earlier this month may have been exposed to measles by a tourist from New Zealand, say health officials from Los Angeles and Orange counties.

AP News Article

FDA: Men Should Be Included in Breast Cancer Clinical Trials

MONDAY, Aug. 26, 2019 (HealthDay News) -- Men should be included in clinical trials of new breast cancer treatments, the U.S. Food and Drug Administration says.

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ACIP Recommendations Updated for 2019-20 U.S. Flu Season

MONDAY, Aug. 26, 2019 (HealthDay News) -- The recommendations of the Advisory Committee on Immunization Practices (ACIP) relating to the use of seasonal influenza vaccines in the United States have been updated for 2019 to 2020; the updated recommendations have been published in the Aug. 23 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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PostRx Antimicrobial Stewardship Feasible in Community Hospitals

MONDAY, Aug. 26, 2019 (HealthDay News) -- Postprescription audit and review (PPR) is a feasible and effective strategy for antimicrobial stewardship in community hospitals, according to a study published online Aug. 16 in JAMA Network Open.

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Editorial

In-Store E-Cigarette Marketing Influences Use in Young People

MONDAY, Aug. 26, 2019 (HealthDay News) -- Recall of electronic nicotine delivery systems (ENDS) marketing at retail stores is associated with increased subsequent ENDS initiation among youth and young adults, according to a study published online Aug. 26 in Pediatrics.

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Risk for Cardiovascular Disease Greater for Childhood Cancer Survivors

MONDAY, Aug. 26, 2019 (HealthDay News) -- Survivors of childhood cancer have an increased risk for all subtypes of cardiovascular disease (CVD), according to a research letter published online Aug. 26 in Circulation.

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Liraglutide Ups Risk for Gallbladder, Biliary Tract Events

MONDAY, Aug. 26, 2019 (HealthDay News) -- There is an increased risk for gallbladder- or biliary tract-related events among patients with type 2 diabetes taking liraglutide versus placebo, according to a study published online Aug. 9 in Diabetes Care.

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Novel Therapy Treats Triple-Class Refractory Multiple Myeloma

FRIDAY, Aug. 23, 2019 (HealthDay News) -- The combination of selinexor and dexamethasone seems effective in treating patients with multiple myeloma that has not responded to standard therapies, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.

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Patient Confidentiality Rule Changes Aim to Fight U.S. Opioid Crisis

FRIDAY, Aug. 23, 2019 (HealthDay News) -- Patient confidentiality rule changes meant to help fight the opioid crisis in the United States have been proposed by the federal government.

AP News Article

Most HPV-Linked Cancers Due to Types Targeted by 9vHPV Vaccine

FRIDAY, Aug. 23, 2019 (HealthDay News) -- Ninety-two percent of human papillomavirus (HPV)-related cancers are attributable to HPV types targeted by the 9-valent HPV vaccine (9vHPV), according to research published in the Aug. 23 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Weight Loss Feasible Regardless of Psychiatric Meds Use

FRIDAY, Aug. 23, 2019 (HealthDay News) -- Participants in a weight loss intervention can lose weight regardless of psychiatric medication use, according to a study published online Aug. 23 in Obesity.

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Low-Cost, Fixed-Dose Polypill Reduces Risk for Major CV Events

FRIDAY, Aug. 23, 2019 (HealthDay News) -- Use of a four-component polypill can effectively reduce the risk for major cardiovascular events, according to a study published in the Aug. 24 issue of The Lancet.

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Editorial (subscription or payment may be required)

As-Needed Inhaler Use an Option for Children With Mild Asthma

FRIDAY, Aug. 23, 2019 (HealthDay News) -- Children with mild asthma can use inhalers as needed, according to a study published online July 30 in the Journal of Allergy and Clinical Immunology: In Practice.

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Antibiotic Use Tied to Higher Risk for Rheumatoid Arthritis

FRIDAY, Aug. 23, 2019 (HealthDay News) -- Antibiotic prescriptions are associated with a higher risk for rheumatoid arthritis (RA), according to a study published online Aug. 7 in BMC Medicine.

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Multidrug-Resistant Salmonella Outbreak Characterized

THURSDAY, Aug. 22, 2019 (HealthDay News) -- A recent multidrug-resistant (MDR) Salmonella enterica serotype Newport outbreak, affecting patients in 32 states, was associated with soft cheese and beef consumption, according to a report published in the Aug. 23 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Coverage With HPV Vaccine Continuing to Increase in Boys

THURSDAY, Aug. 22, 2019 (HealthDay News) -- Coverage with the human papillomavirus (HPV) vaccine increased among boys from 2017 to 2018, according to research published in the Aug. 23 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Opioid Addiction Treatment Used More in States That Expanded Medicaid

THURSDAY, Aug. 22, 2019 (HealthDay News) -- The use of the opioid addiction medication buprenorphine is much higher in states that expanded Medicaid under the Affordable Care Act than in those that did not expand the program, according to a new report from the Urban Institute, a nonprofit research group.

The New York Times Article
Urban Institute Report

Some Cities in Texas Susceptible to Measles Outbreaks

THURSDAY, Aug. 22, 2019 (HealthDay News) -- Some cities in Texas are susceptible to measles outbreaks, according to a study published online Aug. 21 in JAMA Network Open.

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Rx Size Predicts Persistent Opioid Use After Cardiothoracic Surgery

THURSDAY, Aug. 22, 2019 (HealthDay News) -- Prescription size is associated with increased new persistent opioid use among patients after cardiothoracic surgery, according to a study published online Aug. 22 in the Annals of Thoracic Surgery.

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Intensifying BP Meds at Hospital Discharge May Harm Elderly

THURSDAY, Aug. 22, 2019 (HealthDay News) -- Increasing blood pressure medications at hospital discharge for elderly patients hospitalized with noncardiac conditions does not improve long-term outcomes and is tied to short-term harms, according to a study published online Aug. 19 in JAMA Internal Medicine.

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Serelaxin Does Not Lower CV Death in Acute Heart Failure

WEDNESDAY, Aug. 21, 2019 (HealthDay News) -- An infusion of serelaxin does not result in a lower incidence of death from cardiovascular causes or worsening of heart failure among patients hospitalized for acute heart failure, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.

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Editorial (subscription or payment may be required)

Oral Antibiotic Use Linked to Risk for Colorectal Cancer

WEDNESDAY, Aug. 21, 2019 (HealthDay News) -- Oral antibiotic use is associated with an increased risk for colon cancer and a reduced risk for rectal cancer, according to a study published online Aug. 20 in Gut.

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Women With Diabetes More Likely Than Men to Not Take Meds as Prescribed

WEDNESDAY, Aug. 21, 2019 (HealthDay News) -- Women with diagnosed diabetes are more likely than men to not take their medications as prescribed, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Taking Buprenorphine for Opioid Use Disorder May Up Other Med Compliance

WEDNESDAY, Aug. 21, 2019 (HealthDay News) -- Using buprenorphine to treat opioid use disorder (OUD) may increase adherence to treatments for other chronic conditions, according to a study published in the September issue of Medical Care.

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Mobile Stroke Unit Speeds Access to Intraarterial Thrombectomy

WEDNESDAY, Aug. 21, 2019 (HealthDay News) -- Pre-emergency department evaluation on a mobile stroke unit (MSU) can speed access to intraarterial thrombectomy (IAT) compared with standard management by emergency medical services (EMS), according to a study published in the July issue of Stroke.

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DAAs Cut Deaths in Those Treated for HCV-Related Liver Cancer

TUESDAY, Aug. 20, 2019 (HealthDay News) -- Among patients with hepatitis C virus (HCV) infection and complete response to hepatocellular carcinoma (HCC) treatment, direct-acting antiviral (DAA) therapy is associated with a significant reduction in the risk for death, according to a study published online July 30 in Gastroenterology.

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Lipophilic Statins May Cut Liver Cancer in Chronic Viral Hepatitis

TUESDAY, Aug. 20, 2019 (HealthDay News) -- Lipophilic statin use is associated with significantly reduced hepatocellular carcinoma (HCC) incidence and mortality in adults with chronic viral hepatitis, according to a study published online Aug. 20 in the Annals of Internal Medicine.

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Patient Preferences Explored in Multiple Myeloma Treatment

TUESDAY, Aug. 20, 2019 (HealthDay News) -- An Eastern Cooperative Oncology Group (ECOG) performance status of ≥2 is linked to lower treatment satisfaction in patients with relapsed or refractory multiple myeloma (RRMM), but receiving medication orally is linked to higher satisfaction, according to a study published online Aug. 1 in The Oncologist.

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Use of Opioids + Cannabis Tied to Poorer Mental Health

TUESDAY, Aug. 20, 2019 (HealthDay News) -- Adults who take prescription opioids for severe chronic pain are more likely to have increased anxiety, depression, and substance abuse issues if they also use cannabis, according to a study published in the July/August issue of the Journal of Addiction Medicine.

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Certain Dietary Supplements Tied to Dysphagia, Choking in Seniors

TUESDAY, Aug. 20, 2019 (HealthDay News) -- Most reports of swallowing problems caused by dietary supplements involve seniors taking multivitamins or calcium supplements, according to a research letter published online Aug. 20 in the Annals of Internal Medicine.

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Most U.K. Patients With UTI Receive Antibiotics on Same Day

TUESDAY, Aug. 20, 2019 (HealthDay News) -- More than 85 percent of patients with urinary tract infection (UTI) receive antibiotics the same day and more than half are treated with trimethoprim, according to a study published online Aug. 12 in EClinicalMedicine.

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Parents Divided on Primary Care Policies for Unvaccinated Patients

MONDAY, Aug. 19, 2019 (HealthDay News) -- Three in 10 parents say that their child's primary care office should ask parents who refuse all vaccines to find another health care provider, according to an Aug. 19 Mott Poll Report.

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AHA: Prescription Omega-3 Fatty Acids Effectively Lower Triglycerides

MONDAY, Aug. 19, 2019 (HealthDay News) -- After any underlying causes are addressed and diet and lifestyle strategies are implemented, prescription omega-3 fatty acids (n-3 FAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) or EPA only, at a dose of 4 g/day are effective for lowering triglycerides as monotherapy or in combination with other agents, according to an American Heart Association science advisory published online Aug. 19 in Circulation.

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Hypoglycemia Up With Intensive Glucose-Lowering Therapy

MONDAY, Aug. 19, 2019 (HealthDay News) -- Intensive glucose-lowering therapy is prevalent among U.S. adults with diabetes and results in hospitalizations and emergency department visits for hypoglycemia, according to a study published online Aug. 15 in the Mayo Clinic Proceedings.

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Pediatric Cannabis Exposure Up After Medical Legalization

FRIDAY, Aug. 16, 2019 (HealthDay News) -- Following medical marijuana legalization (MML) in Massachusetts in 2012, there was an increase in pediatric cannabis exposure, according to a study published online Aug. 16 in JAMA Network Open.

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More U.K. Pharmacies Giving Patients Pill Organizers

FRIDAY, Aug. 16, 2019 (HealthDay News) -- Pharmacies in the United Kingdom are giving out twice as many pill organizers as they were 10 years ago, according to a study published online July 27 in Research in Social and Administrative Pharmacy.

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Diabetes Education, Support Cuts Hypoglycemia Risk

FRIDAY, Aug. 16, 2019 (HealthDay News) -- Diabetes self-management education and support can cut hypoglycemia risk, according to a review published in the August issue of The Diabetes Educator.

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Intensive BP Therapy Not Beneficial in Nursing Home Residents

FRIDAY, Aug. 16, 2019 (HealthDay News) -- Long-term nursing home residents with hypertension do not experience significant benefits from more intensive antihypertensive treatment, according to a study published online July 22 in the Journal of the American Geriatrics Society.

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SAVED Score Can Predict Risk for VTE in Multiple Myeloma

FRIDAY, Aug. 16, 2019 (HealthDay News) -- For patients with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs), a risk assessment model, SAVED, can predict the risk for venous thromboembolism (VTE), according to a study published in the July issue of the Journal of the National Comprehensive Cancer Network.

Abstract/Full Text

ACIP Recommends Catch-Up HPV Vaccines Through Age 26

THURSDAY, Aug. 15, 2019 (HealthDay News) -- Catch-up human papillomavirus (HPV) vaccinations are recommended for all persons through age 26 years and should be considered for some persons aged 27 to 45 years, according to research published in the Aug. 16 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Patients Recall Few Suggestions for Contact Lens Wear, Care

THURSDAY, Aug. 15, 2019 (HealthDay News) -- About one-third of contact lens wearers recall never hearing any recommendation for lens wear and care from providers, although most providers report sharing recommendations always or most of the time, according to research published in the Aug. 16 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Advertising Can Promote Interest in Health-Related Research

THURSDAY, Aug. 15, 2019 (HealthDay News) -- Advertising current local health-related research using large TV monitors in emergency department waiting rooms can increase the short-term interest in health-related research, according to a study published online Aug. 1 in BMJ Open.

Abstract/Full Text

Cost Burden of Disease Progression High in Multiple Myeloma

THURSDAY, Aug. 15, 2019 (HealthDay News) -- The economic burden of disease progression is considerable among multiple myeloma (MM) patients receiving drug therapy across all lines of therapy (LOTs), according to a study published online Aug. 7 in Leukemia & Lymphoma.

Abstract/Full Text

2005-2016 Saw No Improvement in Diabetes Care Cascade

THURDAY, Aug. 15, 2019 (HealthDay News) -- From 2005 to 2016, there was no improvement in the diabetes care cascade, according to a study published online Aug. 12 in JAMA Internal Medicine.

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Editorial (subscription or payment may be required)

Nonpersistence, Low Adherence to BP Meds Common in Under 65s

THURSDAY, Aug. 15, 2019 (HealthDay News) -- Nonpersistence and low adherence are common among younger adults initiating antihypertensive medications and have not improved over time, according to a study published in the July issue of Hypertension.

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Editorial (subscription or payment may be required)

Antipsychotic Rx Patterns in Children With ADHD Concerning

THURSDAY, Aug. 15, 2019 (HealthDay News) -- Although the number of young people with attention-deficit/hyperactivity disorder (ADHD) who are treated with antipsychotic drugs is low, many antipsychotic prescriptions do not appear to be clinically warranted, according to a study published online July 26 in JAMA Network Open.

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Postoperative Opioid Rx Size Down After Guideline Release

WEDNESDAY, Aug. 14, 2019 (HealthDay News) -- A reduction in postoperative opioid prescription size was observed following release of evidence-based opioid prescribing guidelines in Michigan, according to a research letter published in the Aug. 15 issue of the New England Journal of Medicine.

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Evidence Supports Meds Used for Pain Relief in Pediatric Migraine

WEDNESDAY, Aug. 14, 2019 (HealthDay News) -- Evidence-based therapies are available for the acute symptomatic treatment of migraine in children and adolescents, but evidence is lacking for the impact of many treatments for migraine prevention, according to two updated guidelines published online Aug. 14 in Neurology.

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CDC: Prescription Drug Use Similar in United States, Canada

WEDNESDAY, Aug. 14, 2019 (HealthDay News) -- Use of prescription drugs is similar in the United States and Canada, with almost 70 percent of adults aged 40 to 79 years using at least one prescription drug, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Antiarrhythmic Drugs May Up Fall Injuries in Older A-Fib Patients

WEDNESDAY, Aug. 14, 2019 (HealthDay News) -- Use of antiarrhythmic drugs (AADs) is associated with a higher risk for fall-related injuries and syncope among older patients with atrial fibrillation (AF), according to a study published online July 24 in the Journal of the American Geriatrics Society.

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Editorial

BP From Midlife to Late Life Tied to Risk for Subsequent Dementia

TUESDAY, Aug. 13, 2019 (HealthDay News) -- The risk for subsequent dementia is significantly increased for blood pressure patterns of midlife and late-life hypertension as well as midlife hypertension and late-life hypotension; and intensive blood pressure treatment is associated with a smaller increase in cerebral white matter lesion volume, according to two studies published in the Aug. 13 issue of the Journal of the American Medical Association.

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Doctors Say New Drugs 'Cured' Two Ebola Patients

TUESDAY, Aug. 13, 2019 (HealthDay News) -- New drugs cured two Ebola patients in Congo, showing that people can recover from the highly lethal disease if it is diagnosed and treated early, doctors say.

AP News Article

'Miracle Mineral Solution' Is No Miracle Cure, FDA Warns

TUESDAY, Aug. 13, 2019 (HealthDay News) -- Miracle Mineral Solution, which is sold online as a medical treatment, can cause serious and potentially life-threatening health problems and should not be bought or used by consumers, the U.S. Food and Drug Administration says.

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Comorbid CVD May Up Mortality With ADT for Prostate Cancer

TUESDAY, Aug. 13, 2019 (HealthDay News) -- Elderly prostate cancer patients with preexisting cardiovascular diseases (CVDs) using abiraterone acetate (AA) or enzalutamide (ENZ) have higher short-term mortality compared with their counterparts without CVDs, according to a study published online Aug. 13 in European Urology.

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Methylphenidate Tx Tied to Brain Changes in Boys With ADHD

TUESDAY, Aug. 13, 2019 (HealthDay News) -- Treatment with methylphenidate (MPH) affects specific tracts in brain white matter in boys with attention-deficit/hyperactivity disorder (ADHD), according to a study published online Aug. 13 in Radiology.

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Use of Technology Now Included in Standards of Diabetes Care

MONDAY, Aug. 12, 2019 (HealthDay News) -- A section on the use of technology in the management of diabetes has been added to the American Diabetes Association Standards of Medical Care in Diabetes; a clinical guideline summary was published online Aug. 13 in the Annals of Internal Medicine.

Abstract/Full Text

New Ebola Drugs Highly Effective, Might Shorten Outbreak in Africa

MONDAY, Aug. 12, 2019 (HealthDay News) -- Two experimental Ebola treatments have worked so well in the Democratic Republic of Congo outbreak that they will be offered to all patients, scientists say.

The New York Times Article

Flu Vaccine Tied to Better Long-Term Outcomes in Elderly ICU Survivors

MONDAY, Aug. 12, 2019 (HealthDay News) -- Among elderly patients, influenza vaccination is associated with a reduced risk for dying in the year following discharge from an intensive care unit (ICU), according to a study published in the July issue of Intensive Care Medicine.

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Psychotherapy Alone First Line of Treatment for Depressed Youth

MONDAY, Aug. 12, 2019 (HealthDay News) -- Cognitive behavioral therapy (CBT) should be the first line of treatment in younger patients with major depressive disorder before clinicians prescribe medication, according to a study published online July 29 in The Lancet Psychiatry.

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Editorial (subscription or payment may be required)

Unused Pharmaceuticals Common After Cataract Surgery

MONDAY, Aug. 12, 2019 (HealthDay News) -- Unused pharmaceutical products during phacoemulsification result in relatively high financial and environmental costs, according to a study published online Aug. 1 in JAMA Ophthalmology.

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Editorial (subscription or payment may be required)

Aspirin May Improve Liver Function After Embolization of HCC

MONDAY, Aug. 12, 2019 (HealthDay News) -- Aspirin therapy can improve liver function and survival in patients who have received chemoembolization or transarterial embolization for hepatocellular carcinoma, according to a study published in the September issue of the American Journal of Roentgenology.

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Prescription Drug Misuse Common in High Schoolers

MONDAY, Aug. 12, 2019 (HealthDay News) -- Misuse of prescription drugs is common among high school students, and those misusing prescription drugs frequently obtain them from multiple sources, according to two studies published in the July issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

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Vitamin D Tied to Falls, Nonmotor Symptoms in Parkinson Disease

FRIDAY, Aug. 9, 2019 (HealthDay News) -- In patients with Parkinson disease (PD), vitamin D levels are significantly correlated with falls and some nonmotor symptoms, according to a study published online Aug. 6 in Acta Neurologica Scandinavia.

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Guidelines Issued for Managing Hidradenitis Suppurativa

FRIDAY, Aug. 9, 2019 (HealthDay News) -- In a two-part guideline, published in the July issue of the Journal of the American Academy of Dermatology, the United States and Canadian Hidradenitis Suppurativa Foundations present recommendations for the diagnosis, evaluation, and management of hidradenitis suppurativa.

Abstract/Full Text Part I
Abstract/Full Text Part II

No Evidence for Benefits of Opioids After Pediatric Tonsillectomy

FRIDAY, Aug. 9, 2019 (HealthDay News) -- For children undergoing tonsillectomy, having perioperative opioid fills is not associated with return visits for pain or dehydration, according to a study published online Aug. 8 in JAMA Otolaryngology-Head & Neck Surgery.

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Delayed/Foregone Care More Likely for Cancer Survivors With HDHPs

FRIDAY, Aug. 9, 2019 (HealthDay News) -- Cancer survivors with high-deductible health plans (HDHPs) are more likely to experience delayed or foregone care, according to a study published online Aug. 8 in the Journal of Oncology Practice.

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Warnings Issued to Companies Illegally Selling E-Liquid, Hookah Products

THURSDAY, Aug. 8, 2019 (HealthDay News) -- Warning letters about 44 flavored e-liquid and hookah tobacco products being sold illegally in the United States have been sent to four companies, the U.S. Food and Drug Administration says.

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NSAIDs Contribute to Increased CVD Risk in Osteoarthritis

THURSDAY, Aug. 8, 2019 (HealthDay News) -- Osteoarthritis (OA) is an independent risk factor for increased cardiovascular disease (CVD), and nonsteroidal anti-inflammatory drugs (NSAIDs) contribute substantially to this risk, according to a study published online Aug. 6 in Arthritis & Rheumatology.

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FDA: Approval of Zolgensma Was Based on Manipulated Data

WEDNESDAY, Aug. 7, 2019 (HealthDay News) -- The maker of Zolgensma (onasemnogene abeparvovec-xioi) gave manipulated data to the U.S. Food and Drug Administration when it approved the drug, the agency said Tuesday.

CBS News Article
More Information: FDA

Strong SSRI May Be Tied to Small Decrease in Ischemic Stroke Risk

WEDNESDAY, Aug. 7, 2019 (HealthDay News) -- Antidepressants strongly inhibiting serotonin reuptake may be associated with a small reduction in the rate of ischemic stroke compared with weak reuptake inhibitors, according to a study published online Aug. 7 in Neurology.

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Addition of Sotagliflozin for T1DM Alters Renal Hemodynamics

WEDNESDAY, Aug. 7, 2019 (HealthDay News) -- Sotagliflozin (SOTA), a dual sodium-glucose cotransporter 1 inhibitor (SGLT1i) and SGLT2i, is associated with short- and long-term renal hemodynamic changes in patients with type 1 diabetes, according to a study published online Aug. 1 in Diabetes Care.

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Medicare Spending on Essential Medicines Up 116 Percent From 2011 to 2015

WEDNESDAY, Aug. 7, 2019 (HealthDay News) -- Spending associated with essential medicines grew substantially from 2011 to 2015 for Medicare Part D beneficiaries, according to a study published online July 17 in The BMJ.

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Completion Rates of Recommended Vaccines Lower for Preemies

WEDNESDAY, Aug. 7, 2019 (HealthDay News) -- Preterm infants, including those born late preterm, have a lower rate of completion of recommended vaccines by age 19 months, according to a study published online Aug. 7 in Pediatrics.

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Common Therapy for Obstetric Cholestasis Found Ineffective

WEDNESDAY, Aug. 7, 2019 (HealthDay News) -- For women with intrahepatic cholestasis of pregnancy, treatment with ursodeoxycholic acid does not reduce adverse perinatal outcomes, according to a study published online Aug. 1 in The Lancet.

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Poor Pneumonia Outcomes Tied to Overuse of Broad-Spectrum Antibiotics

TUESDAY, Aug. 6, 2019 (HealthDay News) -- Overuse of broad-spectrum antibiotics is associated with increased mortality and other poor outcomes in adults admitted for community-onset pneumonia, according to a study published in the July 1 issue of the European Respiratory Journal.

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High-Intensity Lipid Lowering May Aid Very Elderly After ACS

TUESDAY, Aug. 6, 2019 (HealthDay News) -- Among patients hospitalized for acute coronary syndrome (ACS), the greatest benefit from simvastatin-ezetimibe compared with simvastatin alone to lower lipid levels was observed in those 75 years of age or older, according to a study published online July 17 in JAMA Cardiology.

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2012 to 2018 Saw Substantial Rise in Naloxone Dispensing

TUESDAY, Aug. 6, 2019 (HealthDay News) -- From 2012 to 2018, there were substantial increases in naloxone dispensing with considerable regional variation, according to research published in the Aug. 6 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Vaccination Does Not Up Risk for Developing Multiple Sclerosis

TUESDAY, Aug. 6, 2019 (HealthDay News) -- Evidence shows that vaccination is not associated with an increased risk for being diagnosed with multiple sclerosis (MS) within the next five years, according to a study published online July 30 in Neurology.

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Reporting of Results Often Biased in Psychiatry, Psychology Trials

TUESDAY, Aug. 6, 2019 (HealthDay News) -- More than half of randomized controlled trials (RCTs) with statistically nonsignificant findings for the primary end points published in psychiatry and psychology journals have spin in the abstract, according to a review published online Aug. 5 in BMJ Evidence-Based Medicine.

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Premature Ovarian Insufficiency Tied to Poor Sleep Quality

MONDAY, Aug. 5, 2019 (HealthDay News) -- Women with premature ovarian insufficiency (POI) receiving hormone therapy have poor sleep quality, according to a study published online July 8 in Menopause.

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Study Explores Dose Ranges for Efpeglenatide in Early T2DM

MONDAY, Aug. 5, 2019 (HealthDay News) -- Efpeglenatide once weekly leads to dose-dependent reductions in glucose and body weight in patients with early type 2 diabetes, according to a phase 2 study published online July 18 in Diabetes Care.

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U.S. Hospital Patients Receive More Opioids Versus Other Countries

FRIDAY, Aug. 2, 2019 (HealthDay News) -- U.S. physicians prescribe opioids more frequently during patient hospitalizations and at discharge compared with physicians in other countries, according to a study published online July 24 in the Journal of Hospital Medicine.

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Brand-Brand Competition Has Not Cut Prices in Pharma Market

FRIDAY, Aug. 2, 2019 (HealthDay News) -- Brand-brand competition in the U.S. pharmaceutical market has not lowered drug list prices, according to a review published online July 30 in PLOS Medicine.

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Compliance With Meds Falters With Age in Youth Born With HIV

FRIDAY, Aug. 2, 2019 (HealthDay News) -- For adolescents with perinatally acquired HIV, the prevalence of medication nonadherence and unsuppressed viral load increases with age, according to a study published online July 3 in AIDS.

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Age-Adjusted Drug Overdose Death Rate Higher in Urban Counties

FRIDAY, Aug. 2, 2019 (HealthDay News) -- In 2017, the age-adjusted rate of drug overdose deaths was higher in urban than rural counties, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Discontinuing Statins Linked to Cardiac Admissions in Elderly

FRIDAY, Aug. 2, 2019 (HealthDay News) -- For elderly patients taking statins for primary prevention, statin discontinuation is associated with an increased risk for admission for any cardiovascular event, according to a study published online July 30 in the European Heart Journal.

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Estrogen Preps Differ in Effects on Heart Fat Deposits

FRIDAY, Aug. 2, 2019 (HealthDay News) -- Hormone therapy formulations have differential effects on heart fat deposits in early menopausal women, according to a study published online Aug. 1 in the Journal of the American Heart Association.

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First Ebola Transmission in Congo City of Goma Reported

THURSDAY, Aug. 1, 2019 (HealthDay News) -- The first transmission of the Ebola virus in Congo's major city of Goma was announced Thursday by the country's health ministry. It said that the disease has been confirmed in the 1-year-old daughter of a man who died of Ebola on Wednesday. The man had symptoms for several days while at home with his large family, CBS News reported.

CBS News Article

Trump Admin Announces Plan to Allow Drug Imports From Canada

THURSDAY, Aug. 1, 2019 (HealthDay News) -- Americans could import less expensive prescription drugs from Canada under a plan being developed by the Trump administration.

HHS Press Release
PhRMA Statement

Recommendations Decreased for Cough, Cold Medicine in U.S.

THURSDAY, Aug. 1, 2019 (HealthDay News) -- There has been a decrease in recommendations for opioid-containing and nonopioid cough and cold medicines (CCM) in the United States, according to a research letter published online July 29 in JAMA Pediatrics.

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Dietary Vitamin A Intake Tied to Reduced Risk for Squamous Cell Carcinoma

THURSDAY, Aug. 1, 2019 (HealthDay News) -- Increased dietary vitamin A seems to be associated with a reduced risk for incident cutaneous squamous cell carcinoma (SCC), according to a study published online July 31 in JAMA Dermatology.

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Ibrutinib-Rituximab Beats Chemoimmunotherapy for CLL

THURSDAY, Aug. 1, 2019 (HealthDay News) -- For patients with previously untreated chronic lymphocytic leukemia (CLL), ibrutinib-rituximab is more efficacious than chemoimmunotherapy, according to a study published in the Aug. 1 issue of the New England Journal of Medicine.

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Asthma Negatively Impacts Work Productivity Worldwide

THURSDAY, Aug. 1, 2019 (HealthDay News) -- Worldwide, asthma patients report that work time is adversely affected by their condition, despite the use of long-term maintenance medication, according to a study published online July 11 in the Journal of Asthma and Allergy.

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One Dose of HPV Vaccine May Be Sufficient in Certain Situations

THURSDAY, Aug. 1, 2019 (HealthDay News) -- One dose of prophylactic human papillomavirus (HPV) vaccine may be as effective as two or three doses in preventing high-grade disease in a high-coverage setting, according to a study published online July 15 in Papillomavirus Research.

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