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March 2020 Briefing - Pharmacy

Last Updated: April 01, 2020.

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for March 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Isradipine Does Not Slow Early Parkinson Disease Progression

TUESDAY, March 31, 2020 (HealthDay News) -- Thirty-six months of treatment with immediate-release isradipine does not slow clinical progression of early-stage Parkinson disease (PD), according to a study published online March 31 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Doctors, Hospitals, Pharmacies Warned Not to Stockpile Meds

TUESDAY, March 31, 2020 (HealthDay News) -- In a joint statement released by the American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists, the professional groups "strongly oppose" physicians, pharmacies, and hospitals prophylactically prescribing medications or purchasing excessive amounts or stockpiles of potential treatments for COVID-19.

Joint Statement

U.S. Army Opens Field Hospital in New York City

MONDAY, March 30, 2020 (HealthDay News) -- The first U.S. Army field hospital for civilian patients opened in New York City Monday and could be the first of many across the nation as it struggles with the coronavirus pandemic.

CBS News Article
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Concomitant Myocardial Injury With COVID-19 Infection Linked to Fatal Outcome

MONDAY, March 30, 2020 (HealthDay News) -- Myocardial injury is associated with fatal outcome in patients with coronavirus disease 2019 (COVID-19), according to research published online March 27 in JAMA Cardiology.

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Editorial

President Extends Social Distancing to April 30 as COVID-19 Cases Surge

MONDAY, March 30, 2020 (HealthDay News) -- As U.S. coronavirus cases and deaths continue to rise, President Donald Trump on Sunday extended strict social distancing guidelines for the country to April 30.

The New York Times Articles
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ED Visit Provides Opportunity to Discuss Contraception With Teens

MONDAY, March 30, 2020 (HealthDay News) -- Emergency departments provide an opportunity to offer contraceptive education to adolescent girls, according to a study recently published in the Journal of Women's Health.

Abstract/Full Text
Editorial

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 23 to 27, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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PPE Negative for SARS-CoV-2 After Patient Contact

FRIDAY, March 27, 2020 (HealthDay News) -- Samples collected from personal protective equipment (PPE) from health care workers (HCWs) caring for patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were negative for SARS-CoV-2, according to research published online March 26 in Infection Control & Hospital Epidemiology.

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Vitamin C May Reduce Ventilation Time in Critically Ill Patients

FRIDAY, March 27, 2020 (HealthDay News) -- The administration of vitamin C shortens the length of mechanical ventilation in critically ill patients, according to a review recently published in the Journal of Intensive Care.

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Workers at Risk for COVID-19 Exposure Can Access Online Training

THURSDAY, March 26, 2020 (HealthDay News) -- The National Institutes of Health has launched a new website with educational resources for hospital employees, emergency first responders, and other workers at risk for exposure to COVID-19.

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Gilead Backs Down on Special Designation for Possible COVID-19 Drug

THURSDAY, March 26, 2020 (HealthDay News) -- Following severe criticism, Gilead Sciences is backing off special designation of its antiviral drug remdesivir -- which shows promise against COVID-19 -- that would have allowed the company to block competition and increase its profits for the drug.

AP News Article

Reduction Noted in Transfusion Burden With Luspatercept

THURSDAY, March 26, 2020 (HealthDay News) -- For patients with transfusion-dependent β-thalassemia, significantly more have a reduction in transfusion burden with receipt of luspatercept versus placebo, according to a study published in the March 26 issue of the New England Journal of Medicine.

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Fostemsavir Active in Multidrug-Resistant HIV-1 Infection

THURSDAY, March 26, 2020 (HealthDay News) -- Among patients with multidrug-resistant HIV-1 infection who have limited therapy options, reductions in HIV-1 RNA level were significantly greater in those who received fostemsavir compared with placebo during the first eight days, according to a study published in the March 26 issue of the New England Journal of Medicine.

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Daily Low-Dose Aspirin Does Not Cut Dementia Risk in Seniors

WEDNESDAY, March 25, 2020 (HealthDay News) -- For relatively healthy older individuals, low-dose aspirin compared with placebo did not reduce the risk for dementia, probable Alzheimer disease, or mild cognitive impairment during a median follow-up of 4.7 years, according to a study published online March 25 in Neurology.

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Editorial (subscription or payment may be required)

FDA Warns of Defective EpiPen Dangers

WEDNESDAY, March 25, 2020 (HealthDay News) -- Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food and Drug Administration warns.

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Many Older Adults Receive Inpatient Diabetes Rx Intensification

WEDNESDAY, March 25, 2020 (HealthDay News) -- One in 10 older adults hospitalized for common medical conditions are discharged with intensified diabetes medications, despite the fact that nearly half are unlikely to benefit from the intensification, according to a study published online March 24 in JAMA Network Open.

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Editorial

National Health Spending Expected to Increase Through 2028

WEDNESDAY, March 25, 2020 (HealthDay News) -- National health expenditures are projected to increase at an average annual rate of 5.4 percent for 2019 to 2028, representing almost 20 percent of U.S. gross domestic product by 2028, according to a study published online March 24 in Health Affairs.

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Proton Pump Inhibitors May Up Fracture Risk in Children

WEDNESDAY, March 25, 2020 (HealthDay News) -- Proton pump inhibitor (PPI) use in children is associated with a small but significant increased risk for any fracture, according to a study published online March 16 in JAMA Pediatrics.

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Triple Therapy Cuts Mortality in Patients With Symptomatic COPD

TUESDAY, March 24, 2020 (HealthDay News) -- A once-daily, three-drug combination treatment reduces mortality for patients with symptomatic chronic obstructive pulmonary disease (COPD) who are at risk for future exacerbations, according to a study published online March 12 in the American Journal of Respiratory and Critical Care Medicine.

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Shortages Seen for Drugs That Show Promise Against COVID-19

TUESDAY, March 24, 2020 (HealthDay News) -- Strong demand for medications that show promise as treatments for COVID-19 have led to shortages of those drugs in the United States.

CBS News Article
Johns Hopkins University

FDA: Insulin Among Drugs Transitioned to Biological Products

TUESDAY, March 24, 2020 (HealthDay News) -- Insulin and other biologic drugs, such as human growth hormone, have now transitioned to being regulated as biological products, providing a new pathway for approval of biosimilars and interchangeable versions of these products and introducing competition into the market, the U.S. Food and Drug Administration announced Monday.

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Interleukin-1β Inhibition Linked to Reduced Incidence of Anemia

TUESDAY, March 24, 2020 (HealthDay News) -- Inhibition of interleukin-1β (IL-1β) with canakinumab is associated with reduced incident anemia as well as improved hemoglobin levels among patients with baseline anemia, according to research published online March 24 in the Annals of Internal Medicine.

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Editorial (subscription or payment may be required)

IDSA Issues Recommendations for COVID-19 Testing

TUESDAY, March 24, 2020 (HealthDay News) -- In a statement published online March 19 by the Infectious Diseases Society of America (IDSA), recommendations are presented for public health and health care professionals to prioritize coronavirus disease 2019 (COVID-19) testing.

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Misconceptions ID'd About COVID-19 Among General Public

MONDAY, March 23, 2020 (HealthDay News) -- In a research letter published online March 20 in the Annals of Internal Medicine, important misconceptions about coronavirus disease 2019 (COVID-19) among the general public in the United States and United Kingdom are presented.

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Iron Chelation Therapy Treats Iron Overload in MDS

MONDAY, March 23, 2020 (HealthDay News) -- Iron chelation therapy (ICT) seems beneficial for iron-overloaded patients with low- or intermediate-1-risk myelodysplastic syndromes (MDS), according to a study published online March 24 in the Annals of Internal Medicine.

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Cumulative Dose of Oral Steroids Associated With HTN Incidence

MONDAY, March 23, 2020 (HealthDay News) -- For adults with any of six chronic inflammatory diseases, a cumulative dose of oral glucocorticoids is associated with an increased incidence of hypertension, according to a study published online March 23 in CMAJ, the journal of the Canadian Medical Association.

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CDC: Modest Decreases Seen in TB Cases, TB-Related Deaths

MONDAY, March 23, 2020 (HealthDay News) -- From 2017 to 2018, there were modest decreases in the number of persons with tuberculosis (TB) and the number of TB-related deaths, according to research published in the March 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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National Guard Activated in Three States as U.S. COVID-19 Cases Rise

MONDAY, March 23, 2020 (HealthDay News) -- As the number of known U.S. coronavirus cases soared past 33,000 and the death count eclipsed 400 on Sunday, President Donald Trump approved disaster declarations for regions hit hardest by the pandemic and activated the National Guard in three states.

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Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 16 to 20, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Statement Addresses Concerns About Heart Meds and COVID-19

FRIDAY, March 20, 2020 (HealthDay News) -- Patients already prescribed angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) should continue taking their medications, according to a joint statement from the American Heart Association (AHA), the Heart Failure Society of America (HFSA), and the American College of Cardiology (ACC), issued in response to a research letter published online March 11 in The Lancet Respiratory Medicine.

Statement
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2017 to 2018 Saw Drop in Overdose Death Rates Involving Opioids

FRIDAY, March 20, 2020 (HealthDay News) -- From 2017 to 2018, there were decreases in overdose death rates involving all opioids, prescription opioids, and heroin, while rates involving synthetic opioids increased, according to research published in the March 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Lopinavir-Ritonavir No Benefit in Adults With Severe COVID-19

FRIDAY, March 20, 2020 (HealthDay News) -- Lopinavir-ritonavir treatment offers no significant benefit over standard care for hospitalized adult patients with severe coronavirus 2019 (COVID-19) infection, according to a study published online March 18 in the New England Journal of Medicine.

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Editorial

2nd Trimester Antibiotic Exposure May Up Risk for Offspring Obesity

FRIDAY, March 20, 2020 (HealthDay News) -- Prenatal antibiotic exposure overall has no significant association with later overweight or obesity in children, but exposure during the second trimester may up later risk, according to a review published online March 3 in Obesity.

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Serial Interval of COVID-19 Estimated at 3.96 Days

FRIDAY, March 20, 2020 (HealthDay News) -- The serial interval of coronavirus 2019 (COVID-19), defined as the time between a primary case and secondary case developing symptoms, is 3.96 days, according to a study published online March 19 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

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Supply Shortages Hinder COVID-19 Testing in the United States

THURSDAY, March 19, 2020 (HealthDay News) -- Shortages of face masks for health care workers, swabs, and other supplies are hampering efforts to increase COVID-19 testing in the United States.

The Washington Post Article
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U.S. Colleges Preparing Empty Dorms to House Coronavirus Patients

THURSDAY, March 19, 2020 (HealthDay News) -- Some U.S. colleges are converting empty dorms into temporary housing for COVID-19 patients.

AP News Article

Opioid Withdrawal Symptoms May Up Health Risks in Drug Injectors

THURSDAY, March 19, 2020 (HealthDay News) -- Among people who inject drugs (PWID), opioid withdrawal symptoms are associated with increased health risks, according to a study published online March 18 in Drug and Alcohol Dependence.

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Trump Signs Massive COVID-19 Relief Package Into Law

THURSDAY, March 19, 2020 (HealthDay News) -- President Donald Trump signed an $850 billion coronavirus relief package into law late Wednesday. The package will provide sick leave, unemployment benefits, and free COVID-19 testing.

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Low Muscle Mass, Density Linked to Shorter Survival in Lymphoma

THURSDAY, March 19, 2020 (HealthDay News) -- The combination of low muscle mass (LMM) and low muscle density (LMD) is associated with shorter survival in patients with diffuse large B-cell lymphoma (DLBCL), according to a study published online March 13 in Leukemia & Lymphoma.

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Antibiotics in First Year of Life May Up Risk for T1DM by Age 10

THURSDAY, March 19, 2020 (HealthDay News) -- Antibiotic prescriptions in the first year of life are associated with an increased risk for type 1 diabetes in childhood, according to a study published online March 4 in Diabetes Care.

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Chinese Researchers Say Flu Drug Effective Against COVID-19

WEDNESDAY, March 18, 2020 (HealthDay News) -- The flu drug favipiravir is "clearly effective" in treating patients with the novel coronavirus, Chinese researchers say.

Daily Mail Article
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U.S. May Not Have Enough Ventilators for COVID-19 Patients

WEDNESDAY, March 18, 2020 (HealthDay News) -- There may not be enough ventilators in the United States to cope with the number of novel coronavirus patients who will require them due to pneumonia and other serious respiratory problems, experts say.

AP News Article
Society of Critical Care Medicine
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Opioid Use Prior to Discharge After C-Section Tied to Later Use

WEDNESDAY, March 18, 2020 (HealthDay News) -- Women who take less opioid pain medication in the 24-hour period before being discharged from the hospital after a cesarean delivery also use less opioid medication during the four weeks following discharge, according to a study published in the March/April issue of the Annals of Family Medicine.

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Metformin Could Reduce Obesity in Children

WEDNESDAY, March 18, 2020 (HealthDay News) -- Metformin treatment reduces some obesity measures in children, according to a review and meta-analysis published online Feb. 18 in Childhood Obesity.

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Medicare Expands Telemedicine Coverage During COVID-19 Pandemic

TUESDAY, March 17, 2020 (HealthDay News) -- Medicare is expanding coverage for telemedicine nationwide so that millions of American seniors can get health care at home and avoid the coronavirus, officials said Tuesday.

AP News Article
Centers for Medicare & Medicaid Services

Noncitizens Undertreated for Cardiovascular Risk Factors

TUESDAY, March 17, 2020 (HealthDay News) -- Noncitizens are undertreated for cardiovascular risk factors in the United States, according to a study published in the March issue of Circulation: Cardiovascular Quality and Outcomes.

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Editorial

New Coronavirus Guidelines Discourage Gatherings of More Than 10

TUESDAY, March 17, 2020 (HealthDay News) -- The Trump Administration on Monday ramped up its coronavirus "social distancing" advisory to now discourage gatherings of more than 10 people.

CNN Article
The President's Coronavirus Guidelines for America
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N.Y. and Colorado Ask Former Health Care Workers to Return to Workforce

MONDAY, March 16, 2020 (HealthDay News) -- Former health care workers in New York State and Colorado are being asked to return to the workforce to help health systems under pressure due to the coronavirus pandemic.

CBS News Article

Race, Insurance Status Linked to Lower Cancer Survival

MONDAY, March 16, 2020 (HealthDay News) -- Nonwhite, uninsured patients with clinically favorable human papillomavirus (HPV)-associated squamous cell carcinoma of the head and neck (SCCHN) have higher mortality than their white peers, according to a study published in the February issue of the Journal of the National Comprehensive Cancer Network.

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Americans Detail Behavior Changes Amid COVID-19 Threat

MONDAY, March 16, 2020 (HealthDay News) -- Many people are changing their behaviors in light of the COVID-19 outbreak, according to a new survey conducted by researchers at the Center for Economic and Social Research at the University of Southern California (USC) Dornsife College of Letters, Arts and Sciences and the Leonard D. Schaeffer Center for Health Policy and Economics.

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Author Conflicts of Interest May Influence Cannabidiol Conclusions

MONDAY, March 16, 2020 (HealthDay News) -- Most articles published between 2014 and 2019 discussing the characteristics, use, and therapeutic effect of cannabidiol (CBD) are supportive, with supportive conclusions in more studies with CBD-related industry funding, according to a research letter published online March 17 in the Annals of Internal Medicine.

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Amid Increased COVID-19 Fears, U.S. Extends Ban on Foreign Travel

MONDAY, March 16, 2020 (HealthDay News) -- In the latest on the coronavirus crisis, the Trump administration on Saturday expanded a 30-day ban on travel from Europe to include residents from the United Kingdom and Ireland, beginning late Monday.

USA Today Article
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Antibiotics May Not Help Children With Suspected Pneumonia

MONDAY, March 16, 2020 (HealthDay News) -- For children with suspected community-acquired pneumonia (CAP) who are discharged from the emergency department, outcomes do not differ between those who do and those who do not receive antibiotic prescriptions, according to a study published online March 16 in Pediatrics.

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Guidance Issued for Interventional Radiologists Treating Frostbite

MONDAY, March 16, 2020 (HealthDay News) -- For interventional radiologists, intraarterial (IA) administration and intravenous (IV) administration of tissue plasminogen activator (tPA) are both useful strategies for treating severe frostbite injuries, according to a review and meta-analysis recently published in the American Journal of Roentgenology.

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Low Maternal Vitamin D May Raise Risk for ADHD in Offspring

MONDAY, March 16, 2020 (HealthDay News) -- There is an association between low maternal vitamin D during early pregnancy and an elevated risk for offspring attention-deficit/hyperactivity disorder (ADHD), according to a study recently published in the Journal of the American Academy of Child & Adolescent Psychiatry.

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President Trump Declares Coronavirus a National Emergency

FRIDAY, March 13, 2020 (HealthDay News) -- President Donald Trump on Friday took a step many political and health care experts have long been urging him to do, declaring the U.S. coronavirus crisis a national emergency.

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Health Coaches Improve Inhaler Use in COPD Patients

FRIDAY, March 13, 2020 (HealthDay News) -- Lay health coaches may improve inhaler technique and adherence for low-income patients with chronic obstructive pulmonary disease (COPD), according to a study published in the January/February issue of the Annals of Family Medicine.

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Editorial

Hep C Testing, Treatment Rates Low at Federally Qualified Health Centers

FRIDAY, March 13, 2020 (HealthDay News) -- The rates of hepatitis C virus (HCV) testing and treatment initiation are low at federally qualified health centers (FQHC) in the United States, according to a study published online March 4 in the Journal of General Internal Medicine.

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Safety, Effectiveness of VKAs, DOACs Similar in General Practice

THURSDAY, March 12, 2020 (HealthDay News) -- For patients receiving anticoagulants, arteriovenous events and major bleeding events do not differ for those receiving vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs), according to a study published in the March/April issue of the Annals of Family Medicine.

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Trump Bans Travel From Most of Europe Amid COVID-19 Fears

THURSDAY, March 12, 2020 (HealthDay News) -- Hoping to curtail the spread of COVID-19 to the United States, travel from most of Europe will be banned for 30 days, President Donald Trump announced Wednesday night.

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WHO Declares Coronavirus a Pandemic

WEDNESDAY, March 11, 2020 (HealthDay News) -- The World Health Organization on Wednesday officially declared the coronavirus outbreak sweeping the globe a pandemic.

World Health Organization
Novel Coronavirus (COVID-19) Situation Map: WHO

Risk for Liver Cancer Down With Low-Dose Aspirin in Hepatitis B, C

WEDNESDAY, March 11, 2020 (HealthDay News) -- Low-dose aspirin is associated with a reduced risk for hepatocellular carcinoma among patients with chronic viral hepatitis, according to a study published in the March 12 issue of the New England Journal of Medicine.

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Number of COVID-19 Cases Tops 1,000 in the United States

WEDNESDAY, March 11, 2020 (HealthDay News) -- Public officials across America raced to curb the spread of coronavirus on Tuesday as the number of U.S. cases topped 1,000, with at least 19 states now declaring states of emergency.

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New HIV PrEP Drug Not Cost-Effective Compared With Generic

WEDNESDAY, March 11, 2020 (HealthDay News) -- Use of tenofovir alafenamide-emtricitabine (F/TAF) is not cost-effective compared with generic tenofovir disoproxil fumarate-emtricitabine (F/TDF) for HIV preexposure prophylaxis (PrEP) among men who have sex with men (MSM), according to a study published online March 10 in the Annals of Internal Medicine.

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Romosozumab Added to Guideline for Management of Osteoporosis

TUESDAY, March 10, 2020 (HealthDay News) -- In an Endocrine Society guideline update, published online in the March issue of the Journal of Clinical Endocrinology & Metabolism, recommendations are presented for the use of romosozumab in the pharmacological management of osteoporosis in postmenopausal women.

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Anticholinergic Burden Tied to Adverse Effects in Middle Age

TUESDAY, March 10, 2020 (HealthDay News) -- Anticholinergic burden (ACB) is associated with adverse outcomes in a middle- to older-aged population, according to a study published in the March/April issue of the Annals of Family Medicine.

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Millions of Coronavirus Test Kits Available Soon, Vice President Says

TUESDAY, March 10, 2020 (HealthDay News) -- Millions of much-needed testing kits for COVID-19 are on the way to clinics and labs nationwide, Vice President Mike Pence told reporters during a White House briefing Monday evening.

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Apixaban Seems Safer Than Rivaroxaban for A-Fib

TUESDAY, March 10, 2020 (HealthDay News) -- Among adults with atrial fibrillation, the rates for ischemic stroke or systemic embolism and bleeding are lower with apixaban compared with rivaroxaban, according to a study published online March 10 in the Annals of Internal Medicine.

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2018 Health Care Spending Up Due to Higher Prices

MONDAY, March 9, 2020 (HealthDay News) -- Average employer-sponsored insurance spending rose to $5,892 per person in 2018, according to the Health Care Cost Institute annual Health Care Cost and Utilization Report.

Health Care Cost and Utilization Report

Fraudulent Coronavirus 'Meds' Targeted by FDA

MONDAY, March 9, 2020 (HealthDay News) -- U.S. officials are cracking down on companies selling fraudulent products that claim to prevent or treat the new coronavirus.

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Adjuvanted FLU-v Vaccine Immunogenic in Healthy Adults

MONDAY, March 9, 2020 (HealthDay News) -- Adjuvanted FLU-v, a broad-spectrum influenza vaccine, is immunogenic, according to a study published online March 10 in the Annals of Internal Medicine.

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Gabapentin Seems Efficacious for Alcohol Use Disorder

MONDAY, March 9, 2020 (HealthDay News) -- Gabapentin appears to be efficacious for the treatment of alcohol use disorder (AUD), especially among those with high alcohol withdrawal, according to a study published online March 9 in JAMA Internal Medicine.

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Rotavirus Vaccination, Type 1 Diabetes Not Linked in Children

MONDAY, March 9, 2020 (HealthDay News) -- Rotavirus vaccination seems not to be associated with type 1 diabetes in children, according to a study published online March 9 in JAMA Pediatrics.

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Multipronged Postoperative Opioid Program Cuts Rx Length

MONDAY, March 9, 2020 (HealthDay News) -- A systemwide, multipronged pain management and opioid reduction program can significantly reduce opioid discharge prescriptions written for more than five days, according to a study published online March 2 in the Journal of the American College of Surgeons.

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Antioxidant Supplements Offer No Benefit in Male Infertility

FRIDAY, March 6, 2020 (HealthDay News) -- Antioxidants do not improve semen parameters or DNA integrity among men with male factor infertility, according to a study published online Feb. 25 in Fertility and Sterility.

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FDA: Cybersecurity Vulnerabilities May Affect Medical Devices

FRIDAY, March 6, 2020 (HealthDay News) -- SweynTooth cybersecurity vulnerabilities may affect medical devices, according to a U.S. Food and Drug Administration safety communication.

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Rates of Unintended Pregnancy Higher in Women With Disabilities

FRIDAY, March 6, 2020 (HealthDay News) -- Pregnancies among women with disabilities are 40 percent more likely to be unintended versus pregnancies among women without disabilities, according to a study published online Feb. 26 in Perspectives on Sexual and Reproductive Health.

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FDA: Singulair to Get 'Black Box' Warning

THURSDAY, March 5, 2020 (HealthDay News) -- Asthma and allergy drug montelukast -- sold as a generic and under the brand name Singulair -- will get a "boxed warning" over potential ties to neuropsychiatric effects, the U.S. Food and Drug Administration announced Wednesday.

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Long-Acting Cabotegravir, Rilpivirine Noninferior in HIV-1

THURSDAY, March 5, 2020 (HealthDay News) -- For patients with HIV-1 suppression, long-acting cabotegravir plus rilpivirine is noninferior to oral therapy with dolutegravir-abacavir-lamivudine and standard oral therapy, according to two studies published online March 4 in the New England Journal of Medicine.

Abstract/Full Text - Orkin (subscription or payment may be required)
Abstract/Full Text - Swindells (subscription or payment may be required)
Editorial (subscription or payment may be required)

Omega-3 Fatty Acids Seem Not to Protect Against Cancer

THURSDAY, March 5, 2020 (HealthDay News) -- Omega-3 fatty acids do not appear to protect against cancer and may only have a small beneficial effect in coronary heart disease, according to two reviews published online Feb. 29 in the British Journal of Cancer and the Cochrane Library.

Abstract/Full Text - Hanson (subscription or payment may be required)
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Repeat ED Visits for Opioid-Related Emergencies on the Rise

THURSDAY, March 5, 2020 (HealthDay News) -- Emergency departments are increasingly seeing patients for repeat opioid-related care, according to a study recently published in the Annals of Emergency Medicine.

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Habitual Fish Oil Supplements Linked to Lower CVD Risk

THURSDAY, March 5, 2020 (HealthDay News) -- Habitual supplementation with fish oil is associated with a reduced risk for cardiovascular disease (CVD) outcomes and all-cause mortality, according to a study published online March 4 in The BMJ.

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Antimalarials May Cut Risk for Type 2 Diabetes in Lupus Patients

THURSDAY, March 5, 2020 (HealthDay News) -- Adherence to antimalarials may offer a protective effect against type 2 diabetes mellitus (T2DM) among patients with systemic lupus erythematosus (SLE), according to a study recently published in Arthritis Care & Research.

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Smartphone Use Linked to Increased Meds Required for Headache

WEDNESDAY, March 4, 2020 (HealthDay News) -- Use of smartphones seems to be associated with increased requirements for acute medication for headache and less relief with acute medication, according to a study published online March 4 in Neurology Clinical Practice.

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Editorial (subscription or payment may be required)

EHR Use Up in Residential Care Communities 2012 to 2016

WEDNESDAY, March 4, 2020 (HealthDay News) -- From 2012 to 2016, there was an increase in electronic health record (EHR) use among residential care communities, according to a study published online March 3 in the National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Molecularly Matched Therapy Promising in Pancreatic Cancer

WEDNESDAY, March 4, 2020 (HealthDay News) -- Receipt of molecularly matched therapy is associated with improved outcomes in patients with pancreatic cancer, according to a study published online March 2 in The Lancet Oncology.

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Racial/Ethnic Insurance Coverage Disparity Down Since ACA

WEDNESDAY, March 4, 2020 (HealthDay News) -- Since the implementation of coverage expansions associated with the Affordable Care Act (ACA), the disparities in insurance coverage related to race and ethnicity have decreased, according to a study published in the March issue of Health Affairs.

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Considerable Increase Seen in List, Net Prices of Branded Drugs

WEDNESDAY, March 4, 2020 (HealthDay News) -- From 2007 to 2018, there were substantial increases in list and net prices of branded drugs in the United States, according to a study published in the March 3 issue of the Journal of the American Medical Association.

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Serum Folate Tied to CV Mortality Risk in Rheumatoid Arthritis

WEDNESDAY, March 4, 2020 (HealthDay News) -- Among patients with rheumatoid arthritis (RA), a serum folate level of at least 4.3 ng/mL is associated with lower cardiovascular (CV) mortality risk, according to a study published online Feb. 26 in JAMA Network Open.

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Short-Term Medications May Cut Risk for 'Broken Heart' Syndrome

WEDNESDAY, March 4, 2020 (HealthDay News) -- In early bereavement, low-dose metoprolol and aspirin reduce physiological and psychological surrogate measures of cardiovascular risk, according to a study published in the February issue of the American Heart Journal.

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Recommendations Provided for Treatment of Ulcerative Colitis

WEDNESDAY, March 4, 2020 (HealthDay News) -- In a new clinical guideline from the American Gastroenterological Association, recently published in Gastroenterology, treatment recommendations are presented for patients with moderate-to-severe ulcerative colitis (UC).

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1996 to 2016 Saw Increases in U.S. Spending on Health Care

TUESDAY, March 3, 2020 (HealthDay News) -- From 1996 to 2016, there were considerable increases in U.S. spending on health care, according to a study published in the March 3 issue of the Journal of the American Medical Association.

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NICE Guidelines Presented for Management of Thyroid Disease

TUESDAY, March 3, 2020 (HealthDay News) -- In a summary of a recent guideline from the National Institute for Health and Care Excellence (NICE), published online Jan. 29 in The BMJ, recommendations are presented for the assessment and management of thyroid disease.

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Repeated Courses of Antibiotics Linked to Hospital Admission


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