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April 2020 Briefing - Internal Medicine

Last Updated: May 01, 2020.

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for April 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Symptomatic Health Care Staff in U.K. Screened for COVID-19

THURSDAY, April 30, 2020 (HealthDay News) -- Screening symptomatic health care workers for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is feasible during the pandemic, according to a research letter published online April 22 in The Lancet.

Abstract/Full Text (subscription or payment may be required)

Study Explores Outcomes Valued by Glomerular Disease Patients

THURSDAY, April 30, 2020 (HealthDay News) -- Patients with glomerular disease and their caregivers give highest priority to outcomes of kidney function, mortality, and need for dialysis or transplant, but they also prioritize life participation and fatigue, according to a study published online April 30 in the Clinical Journal of the American Society of Nephrology.

Abstract/Full Text (subscription or payment may be required)

Remdesivir May Accelerate Recovery From Severe COVID-19

THURSDAY, April 30, 2020 (HealthDay News) -- Remdesivir may speed time to clinical improvement for patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, although results are conflicting, according to a study published online April 29 in The Lancet and press releases issued regarding a National Institutes of Health (NIH)-sponsored study.

Abstract/Full Text - Wang (subscription or payment may be required)
Editorial (subscription or payment may be required)
Press Release

Pandemic Disrupting Health Care for 55 Percent of Older Adults

THURSDAY, April 30, 2020 (HealthDay News) -- At least half of older adults report experiencing a disruption to their medical care at one month into social distancing in response to the COVID-19 pandemic, according to a survey released April 27 by NORC at University of Chicago.

Press Release

Psoriasis Tied to Higher Alzheimer Disease Risk

THURSDAY, April 30, 2020 (HealthDay News) -- The incidence of Alzheimer disease (AD) is significantly higher in patients with psoriasis versus individuals without psoriasis, according to a Korean study published online April 15 in Scientific Reports.

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Food Insecurity Rates High Amid COVID-19 Pandemic

THURSDAY, April 30, 2020 (HealthDay News) -- Food insecurity in the United States is high as a result of the COVID-19 pandemic, according to a survey released April 23 by the University of Arkansas Community and Family Institute.

Press Release

NT-proBNP Does Not Improve Evaluation of Syncope in the ED

THURSDAY, April 30, 2020 (HealthDay News) -- For adult emergency department (ED) patients with syncope, serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) does not improve prognostication above the Canadian Syncope Risk Score (CSRS), according to a study published online April 28 in the Annals of Internal Medicine.

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Rate, Timing of Altered Smell, Taste in Mild COVID-19 Examined

THURSDAY, April 30, 2020 (HealthDay News) -- Mildly symptomatic patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often have alterations in smell or taste, according to a research letter published online April 22 in the Journal of the American Medical Association.

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Mental Disorders May Up Risk for Subsequent Medical Conditions

THURSDAY, April 30, 2020 (HealthDay News) -- The presence of a mental disorder is associated with an increased risk for many subsequent medical conditions, according to a study on a Danish population cohort published online April 30 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Large-Vessel Stroke Described in Young Adults With COVID-19

THURSDAY, April 30, 2020 (HealthDay News) -- Cases of large-vessel stroke in individuals younger than 50 years are described in patients with COVID-19 in a case report published online April 28 in the New England Journal of Medicine.

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NIH Launches $500 Million Contest to Produce Best COVID-19 Test

THURSDAY, April 30, 2020 (HealthDay News) -- A competition between researchers is part of a $1.5 billion program that seeks to speed development of accurate, quick, and easy-to-use COVID-19 tests, the U.S. National Institutes of Health (NIH) announced Wednesday.

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Men Have More Serious Disease, Higher Death Rate From COVID-19

THURSDAY, April 30, 2020 (HealthDay News) -- For patients with COVID-19, male gender is associated with worse outcomes, independent of age, according to a study published online April 29 in Frontiers in Public Health.

Abstract/Full Text (subscription or payment may be required)

Medicaid Expansion Tied to Higher Mammography Rates

THURSDAY, April 30, 2020 (HealthDay News) -- Total insurance coverage, Medicaid coverage, and mammogram rates are higher among lower-income women living in Medicaid expansion states versus nonexpansion states, according to a study published online April 6 in the Journal of the American College of Surgeons.

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14.9 Percent of U.S. Adults Had Ever Used an E-Cigarette in 2018

THURSDAY, April 30, 2020 (HealthDay News) -- In 2018, 14.9 percent of U.S. adults had ever used an electronic cigarette (e-cigarette) and 3.2 percent were current users, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Smoking Tied to Inferior Survival in Acute Myeloid Leukemia

WEDNESDAY, April 29, 2020 (HealthDay News) -- Smoking status is an important patient-related prognostic factor for outcome in patients with acute myeloid leukemia (AML) treated with intensive chemotherapy, according to a study published online April 21 in the British Journal of Haematology.

Abstract/Full Text

Almost All COVID-19 Patients Have Diminished Sense of Smell

WEDNESDAY, April 29, 2020 (HealthDay News) -- Quantitative smell testing shows that decreased smell function is a major marker for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online April 17 in the International Forum of Allergy & Rhinology.

Abstract/Full Text

Guidelines Recommended for ECMO Use in Setting of Pandemic

WEDNESDAY, April 29, 2020 (HealthDay News) -- Hospitals should have a formal plan to respond to the increasing need for extracorporeal membrane oxygenation (ECMO) in the setting of a pandemic such as COVID-19, according to a study published online April 15 in the Annals of the American Thoracic Society.

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Pediatric Brain Cancer Outcomes Worse for Black, Hispanic Patients

WEDNESDAY, April 29, 2020 (HealthDay News) -- Treatment disparities may explain worse outcomes for pediatric black and Hispanic brain cancer patients, according to a study recently published in Scientific Reports.

Abstract/Full Text

Many Health Care Workers Face Risk for Poor Outcomes With COVID-19

WEDNESDAY, April 29, 2020 (HealthDay News) -- More than one-quarter of health care workers with patient contact are at risk for poor outcomes from COVID-19, according to a study published online April 28 in the Annals of Internal Medicine.

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David Shulkin, M.D., on COVID-19 Financial Consequences for Health Care System

MONDAY, April 27, 2020 (HealthDay News) -- Health care organizations are facing hard financial decisions amid the COVID-19 pandemic, but an end is in sight as some are beginning to slowly open back up around the country, according to David Shulkin, M.D. Shulkin, who served as ninth secretary for Veterans Affairs and is former president and CEO of Beth Israel Medical Center in New York, spoke with HealthDay during a live stream on the HealthDay YouTube channel and live blog.

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KIMT3 Article

USPSTF: Behavioral Interventions Likely Prevent Tobacco Use

WEDNESDAY, April 29, 2020 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) concludes that primary care-feasible behavioral interventions have a moderate net benefit for preventing tobacco use in children. These findings form the basis of a final recommendation statement, published online April 28 in the Journal of the American Medical Association.

Evidence Report (subscription or payment may be required)
Recommendations (subscription or payment may be required)
Editorial (subscription or payment may be required)

Primary PCI Remains Standard of Care for STEMI During COVID-19

WEDNESDAY, April 29, 2020 (HealthDay News) -- Primary percutaneous coronary intervention (PCI) remains the standard of care for patients with ST-elevation myocardial infarction (STEMI) during the COVID-19 pandemic, according to a consensus statement published online April 20 in the Journal of the American College of Cardiology.

Abstract/Full Text (subscription or payment may be required)

Rheumatoid Arthritis Patients Remain Unaware of CV Risk

WEDNESDAY, April 29, 2020 (HealthDay News) -- Patients with rheumatoid arthritis (RA) have low awareness about associated cardiovascular (CV) risk, according to a study published online April 20 in ACR Open Rheumatology.

Abstract/Full Text

GI Manifestations Seen for Nearly One in Three With SARS-CoV-2

WEDNESDAY, April 29, 2020 (HealthDay News) -- A considerable proportion of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have gastrointestinal manifestations, according to a study involving patients at a U.S. hospital published online April 10 in Gastroenterology.

Abstract/Full Text (subscription or payment may be required)

Low Vitamin D, Smoking Predict Worse Cognitive Function in MS

WEDNESDAY, April 29, 2020 (HealthDay News) -- For multiple sclerosis (MS) patients with clinically isolated syndrome, lower vitamin D and smoking predict worse long-term cognitive function and neuronal integrity, according to a study published online April 16 in Neurology.

Abstract/Full Text (subscription or payment may be required)

Major Depression Reduced for Those Reared in Adoptive Homes

WEDNESDAY, April 29, 2020 (HealthDay News) -- Individuals at high risk for major depression reared in adoptive homes have a significantly reduced risk for major depression compared with those raised in their home environment, according to a study published online April 28 in the American Journal of Psychiatry.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Multicancer Blood Test, PET-CT Combo Feasible for Cancer Screen

WEDNESDAY, April 29, 2020 (HealthDay News) -- Multicancer blood testing combined with positron emission tomography-computed tomography (PET-CT) imaging can detect cancers, according to a study published online April 28 in Science to coincide with the virtual annual meeting of the American Association for Cancer Research.

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Thromboembolic Complications in COVID-19 Discussed

WEDNESDAY, April 29, 2020 (HealthDay News) -- Prevention, diagnosis, and therapeutic management of thromboembolic complications in COVID-19 are discussed in a report published online April 23 in Radiology.

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Reviews Assess Tools to Identify, Diagnose, Treat Alzheimer Dementia

WEDNESDAY, April 29, 2020 (HealthDay News) -- Limited tools are available for identifying, diagnosing, and treating cognitive dysfunction from Alzheimer disease, according to three studies published online April 28 in the Annals of Internal Medicine.

Abstract/Full Text -- Hemmy (subscription or payment may be required)
Abstract/Full Text -- Fink Study 1 (subscription or payment may be required)
Abstract/Full Text -- Fink Study 2 (subscription or payment may be required)
Editorial (subscription or payment may be required)

Nearly Half of U.S. Population Breathes Unhealthy Air

TUESDAY, April 28, 2020 (HealthDay News) -- Climate change continues to make air pollution worse, with 45.8 percent of the U.S. population living in counties with unhealthy ozone or particle pollution, according to the American Lung Association (ALA) 21st annual State of the Air report.

State of the Air Report

Low Vitamin D May Reduce Survival for Some With Multiple Myeloma

TUESDAY, April 28, 2020 (HealthDay News) -- Vitamin D deficiency is associated with reduced overall survival for patients with multiple myeloma (MM), with a differential effect across race, according to a study published online April 21 in Blood Advances.

Abstract/Full Text

Most SARS-CoV-2-Positive Pregnant Women Asymptomatic at Screening

TUESDAY, April 28, 2020 (HealthDay News) -- Universal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing of pregnant women presenting for delivery in New York City revealed that most positive patients were asymptomatic, according to a research letter published online April 13 in the New England Journal of Medicine.

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National Coronavirus Testing Strategy Announced as U.S. Cases Top 1 Million

TUESDAY, April 28, 2020 (HealthDay News) -- While health experts continued to call for a national strategy to test more Americans for coronavirus, President Donald Trump on Monday announced a "blueprint" for boosting testing capacity as some states began reopening their economies.

Washington Post Article
CBS News Article
New York Times Article

Rare, Serious Illness May Occur in Children With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) -- Abdominal pain, gastrointestinal complaints, and heart inflammation are among the symptoms in children with a rare syndrome that may be linked to COVID-19, British health officials say.

CNN Article

Upward Income Mobility Tied to Worse Cardiometabolic Health

TUESDAY, April 28, 2020 (HealthDay News) -- Upward income mobility is associated with lower perceived stress and fewer depressive symptoms but with higher rates of metabolic syndrome, according to a study published online April 28 in the Journal of the American Heart Association.

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Job Strain Linked to Increase in Risk for PAD Hospitalization

TUESDAY, April 28, 2020 (HealthDay News) -- Job strain is associated with a 1.41-fold increase in the average risk for peripheral artery disease (PAD) hospitalization, according to a study published online April 28 in the Journal of the American Heart Association.

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45.4 Percent of U.S. Adults at Risk for Complications With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) -- An estimated 45.4 percent of U.S. adults may have an increased risk for COVID-19 complications due to chronic conditions, according to a study published in the August issue of Emerging Infectious Diseases.

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High Rate of Pulmonary Embolism Found for Patients With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) -- COVID-19 is associated with a high rate of pulmonary embolism, according to two research letters published online April 23 in Radiology.

Abstract/Full Text -- Leonard-Lorant (subscription or payment may be required)
Abstract/Full Text -- Grillet (subscription or payment may be required)

Adding High-Dose Chloroquine Not Advised for Severe COVID-19

TUESDAY, April 28, 2020 (HealthDay News) -- High-dosage chloroquine diphosphate (CQ) has potential safety hazards when used as adjunctive therapy for patients hospitalized with severe COVID-19, according to a study published online April 24 in JAMA Network Open.

Abstract/Full Text
Editorial

Social Inequality May Contribute to Poor Metabolic, Bone Health

TUESDAY, April 28, 2020 (HealthDay News) -- Social factors might be significant contributors to coexisting metabolic syndrome (MetS) and osteoporosis (OP) in postmenopausal women, according to a study published online April 20 in Menopause.

Abstract/Full Text (subscription or payment may be required)

Diabetes Medication Prescribing Increased 2003 to 2016

TUESDAY, April 28, 2020 (HealthDay News) -- Pharmacologic treatment for type 2 diabetes increased from 2003 to 2016, according to a study published online March 31 in Diabetes Care.

Abstract/Full Text (subscription or payment may be required)

Patients Aged 60 to 69 Most Often Hospitalized With COVID-19

TUESDAY, April 28, 2020 (HealthDay News) -- Persons aged 60 to 69 years with COVID-19 are the most commonly hospitalized, according to a research letter published online April 24 in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)

Neurologic Features Tied to ARDS in Severe COVID-19 Described

MONDAY, April 27, 2020 (HealthDay News) -- Acute respiratory distress syndrome (ARDS) due to COVID-19 is associated with neurologic features, including encephalopathy, agitation, and confusion, according to a letter to the editor published online April 15 in the New England Journal of Medicine.

Abstract/Full Text

FDA Warns of Bogus Claims by Makers of Hand Sanitizer

MONDAY, April 27, 2020 (HealthDay News) -- Some companies are selling hand sanitizers with unproven claims that they will protect against COVID-19, the U.S. Food and Drug Administration warns.

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Hearing Loss Linked to Postural Instability in Older Adults

MONDAY, April 27, 2020 (HealthDay News) -- The odds of postural instability are increased in older adults with moderate or worse hearing loss, even when hearing loss is present on only one side, according to a study published online April 23 in JAMA Otolaryngology-Head & Neck Surgery.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Pulse Oximetry May Be Overused in Infants With Bronchiolitis

MONDAY, April 27, 2020 (HealthDay News) -- Use of monitoring with continuous pulse oximetry for infants with bronchiolitis who do not require supplemental oxygen varies widely by hospital, according to a study published in the April 21 issue of the Journal of the American Medical Association.

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Editorial (subscription or payment may be required)

SARS-CoV-2 Not Detected in Semen After COVID-19 Recovery

MONDAY, April 27, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not detected in the semen of patients one month after COVID-19 diagnosis, according to a study published online April 17 in Fertility and Sterility.

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Direct Medical Costs of COVID-19 Infection Are Considerable

MONDAY, April 27, 2020 (HealthDay News) -- A single symptomatic COVID-19 infection results in direct medical costs of $3,045 in the United States, according to a study published online April 23 in Health Affairs.

Abstract/Full Text

Former Footballers Report Chronic Traumatic Encephalopathy Symptoms

MONDAY, April 27, 2020 (HealthDay News) -- A number of former American-style football (ASF) players report clinician-diagnosed chronic traumatic encephalopathy (CTE), and they have significantly more comorbidities and cognitive impairment symptoms, according to a study published online April 13 in the Annals of Neurology.

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Mobile BP Monitoring Does Not Change Outcomes After Myocardial Infarction

MONDAY, April 24, 2020 (HealthDay News) -- The use of smartphone-enabled health monitoring devices after myocardial infarction yields similar blood pressure control when compared with regular follow-up visits, according to a study published online April 16 in JAMA Network Open.

Abstract/Full Text
Editorial

Physician's Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of April 20 to 24, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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HTN, Obesity, Diabetes Common in U.S. COVID-19 Patients

FRIDAY, April 24, 2020 (HealthDay News) -- The most common comorbidities among patients hospitalized with COVID-19 in the New York City area are hypertension, obesity, and diabetes, according to a study published online April 22 in the Journal of the American Medical Association.

Abstract/Full Text

FDA Warns About Treating COVID-19 With Unproven Drugs

FRIDAY, April 24, 2020 (HealthDay News) -- Malaria drugs touted by some as potential "game changers" against COVID-19 are actually too dangerous for general use, the U.S. Food and Drug Administration warned Americans on Friday.

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Premature Posting of Remdesivir Findings Were 'Inconclusive'

FRIDAY, April 24, 2020 (HealthDay News) -- Inconclusive findings from a study investigating the antiviral drug remdesivir as a treatment for COVID-19 were posted to the World Health Organization website "prematurely," drug maker Gilead Sciences said Thursday.

CNN Article

COVID-19 Pandemic Delays FDA Review of Vaping Products

FRIDAY, April 24, 2020 (HealthDay News) -- A review of vaping products has been delayed by the COVID-19 outbreak, the U.S. Food and Drug Administration announced Thursday.

AP News Article

Americans Report Concerns Over Their Mental Health During Pandemic

FRIDAY, April 24, 2020 (HealthDay News) -- Mental health concerns top economic worries during the COVID-19 pandemic, according to the results of a survey released by the University of Phoenix.

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Infection Rate Up Prior to Detection of Malignant Cancer

FRIDAY, April 24, 2020 (HealthDay News) -- The rate of infection with influenza, gastroenteritis, hepatitis, and pneumonia is increased before detection of malignant cancer, according to a study published online April 17 in Cancer Immunology Research.

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Prevalence of Hypertension in U.S. 45.4 Percent in 2017 to 2018

FRIDAY, April 24, 2020 (HealthDay News) -- In 2017 to 2018, 45.4 percent of adults had hypertension, with prevalence higher among men than women, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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COVID-19 Outcomes Worse With Diabetes, Hyperglycemia

FRIDAY, April 24, 2020 (HealthDay News) -- Diabetes and/or uncontrolled hyperglycemia occur frequently among hospitalized patients with COVID-19 and are associated with worse outcomes, according to a study accepted for publication in the Journal of Diabetes Science and Technology.

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COVID-19-Linked Changes Reported in Rheumatic Disease Patient Care

FRIDAY, April 24, 2020 (HealthDay News) -- Changes to health care have been reported among patients with rheumatic diseases during the COVID-19 pandemic, according to a study published online April 20 in ACR: Open Rheumatology.

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SARS-CoV-2 Stays in Respiratory Samples Longer in Severely Ill

FRIDAY, April 24, 2020 (HealthDay News) -- The median duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is significantly longer in the respiratory samples of patients with severe versus mild disease, according to a study published online April 21 in The BMJ.

Abstract/Full Text

SARS-CoV-2 Can Spread Rapidly in Homeless Shelters

THURSDAY, April 23, 2020 (HealthDay News) -- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can spread rapidly in homeless shelters, according to two studies published in the April 22 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text - Tobolowsky
Abstract/Full Text - Mosites

CDC: More Chemical Exposures Reported in January to March 2020

THURSDAY, April 23, 2020 (HealthDay News) -- In January to March 2020, there were more chemical exposures reported to the National Poison Data System than in the corresponding months of 2019 and 2018, according to research published in the April 20 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

White House Announces Payment Plan for Uninsured COVID-19 Patients

THURSDAY, April 23, 2020 (HealthDay News) -- A plan to begin paying hospitals and doctors who treat uninsured COVID-19 patients was announced by U.S. Health and Human Services Secretary Alex Azar on Wednesday.

AP News Article

'Health Force' to Combat Pandemic Proposed by U.S. Senators

THURSDAY, April 23, 2020 (HealthDay News) -- A bill to create a "Health Force" to help combat the U.S. COVID-19 outbreak has been announced by two Democratic senators.

NBC News Article

ACEIs/ARBs Not Linked to Severity or Mortality of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- For patients with hypertension hospitalized with COVID-19 infections, angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) are not associated with the severity or mortality of COVID-19, according to a brief report published online April 23 in JAMA Cardiology.

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Visual Impairment May Up Risk for Dementia in Older Women

THURSDAY, April 23, 2020 (HealthDay News) -- In older women, objectively measured visual impairment is associated with a twofold to more than fivefold increased risk for dementia, according to a study published online April 16 in JAMA Ophthalmology.

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Yoga Cuts Testosterone in Women With Polycystic Ovary Syndrome

THURSDAY, April 23, 2020 (HealthDay News) -- A mindful yoga intervention reduces testosterone levels in women with polycystic ovary syndrome (PCOS), according to a study published online April 14 in the Journal of the American Osteopathic Association.

Abstract/Full Text

Clascoterone Cream Safe, Effective for Acne Treatment

THURSDAY, April 23, 2020 (HealthDay News) -- Clascoterone cream, 1 percent, appears to be safe and effective for the treatment of acne, according to a study published online April 22 in JAMA Dermatology.

Abstract/Full Text
Editorial

Lopinavir/Ritonavir, Umifenovir Ineffective for Mild COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- For patients hospitalized with mild/moderate COVID-19, lopinavir/ritonavir (LPV/r) or umifenovir (Arbidol) monotherapy offers little benefit, according to a study published online April 17 in Med.

Abstract/Full Text

AAD Establishes Registry for Skin Manifestations of COVID-19

THURSDAY, April 23, 2020 (HealthDay News) -- A registry has been created for reporting skin manifestations of COVID-19 following reports of patients presenting with skin conditions, including findings outlined in a letter to the editor published online March 26 in the Journal of the European Academy of Dermatology and Venereology.

Registry
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Chronic Conditions, Obesity Common in Fatal Cases of EVALI

THURSDAY, April 23, 2020 (HealthDay News) -- Chronic conditions, including asthma, mental health conditions, and obesity, are common among fatal cases of e-cigarette, or vaping, product use-associated lung injury (EVALI), according to a study published in the April 23 issue of the New England Journal of Medicine.

Abstract/Full Text
Editorial

Higher Manganese Intake May Be Tied to Lower Type 2 Diabetes Risk

THURSDAY, April 23, 2020 (HealthDay News) -- Higher intake of manganese is associated with a lower type 2 diabetes risk among postmenopausal women, independent of known risk factors, according to a study published online April 15 in Diabetes Care.

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Housing Insecurity May Increase Risk for Incident Kidney Disease

THURSDAY, April 23, 2020 (HealthDay News) -- Housing insecurity is tied to an increased risk for developing albuminuria, according to a study published March 31 in Kidney360.

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Firework-Related ED Visits Peak Around Independence Day

WEDNESDAY, April 22, 2020 (HealthDay News) -- Most emergency department admissions for firework-related injuries occur near Independence Day and New Year's Day, involve men and people younger than 18, and are caused by firecrackers and bottle rockets, according to a study published online April 9 in JAMA Ophthalmology.

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Hydroxychloroquine Seems Not to Cut Ventilator Use in COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is no evidence that use of hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) reduces the risks for mechanical ventilation or death from any cause in patients hospitalized with COVID-19, according to a study that has not yet been peer reviewed and was posted online April 21 at medRxiv.org.

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Processed Meat, Unhealthy Snack Food Networks Tied to Dementia

WEDNESDAY, April 22, 2020 (HealthDay News) -- Focused eating habits with high processed meats and unhealthy snacking may be associated with increased dementia risk, according to a study published online April 22 in Neurology.

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Expert Panel: There Are No Proven Drug Treatments for COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is no proven drug treatment for COVID-19 patients, according to a panel of experts convened by the U.S. National Institute of Allergy and Infectious Diseases.

The New York Times Article

Rapid COVID-19 Test Can Produce False Negatives

WEDNESDAY, April 22, 2020 (HealthDay News) -- A widely used rapid COVID-19 test can produce false negatives if a certain solution is used to move or store patients' samples, the test's maker said.

CNN Article

Premature Mortality Rates Up for CAD in Women From Rural U.S.

WEDNESDAY, April 22, 2020 (HealthDay News) -- According to the findings of two studies published online April 20 in the Journal of the American Heart Association, coronary artery disease (CAD) mortality rates have increased among women from rural areas, while social determinants of health (SDOH) increase the risk for 90-day mortality after heart failure hospitalization.

Abstract/Full Text - Bossard (subscription or payment may be required)
Abstract/Full Text - Sterling (subscription or payment may be required)

ST-Segment Elevation Described in Patients With COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- For patients with COVID-19 who have ST-segment elevation, indicating potential acute myocardial infarction, there is considerable variability in presentation, and prognosis is poor, according to a letter to the editor published online April 17 in the New England Journal of Medicine.

Abstract/Full Text

2015 to 2018 Saw High Total Cholesterol for 11.4 Percent of U.S. Adults

WEDNESDAY, April 22, 2020 (HealthDay News) -- Overall, 11.4 percent of adults had high total cholesterol during 2015 to 2018, according to an April data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

Abstract/Full Text

Clinical, Genetic, Biomarker Model IDs Risk for Pancreatic Cancer

WEDNESDAY, April 22, 2020 (HealthDay News) -- A model that includes data on clinical and genetic factors and circulating biomarkers may improve risk discrimination for pancreatic cancer, according to a study published online April 22 in Cancer Epidemiology, Biomarkers & Prevention.

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Heart Rate Variability Related to Risk for Incident Diabetes

WEDNESDAY, April 22, 2020 (HealthDay News) -- Altered heart rate variability (HRV) may be related to risk for incident diabetes in young Asian adults, according to a study published online April 16 in Diabetes Care.

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Living Alone Ups Admission Risk for Respiratory Disease in Seniors

WEDNESDAY, April 22, 2020 (HealthDay News) -- For older adults, the risk for hospital admission due to respiratory disease (RD) is increased in association with living alone and social disengagement, according to a study published online April 21 in Thorax.

Abstract/Full Text

Obesity Ups Risk for COVID-19 Severity

WEDNESDAY, April 22, 2020 (HealthDay News) -- There is a high frequency of obesity among patients admitted to intensive care for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a study published online April 9 in Obesity.

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Scoring System Helps Guide Surgical Care During COVID-19

WEDNESDAY, April 22, 2020 (HealthDay News) -- A scoring system for medically necessary time-sensitive (MeNTS) procedures can facilitate decision making and triage in the setting of COVID-19, according to a study published online April 9 in the Journal of the American College of Surgeons.

Abstract/Full Text

Alone, Low Vitamin D Does Not Cause Osteoporotic Fractures

WEDNESDAY, April 22, 2020 (HealthDay News) -- While low blood levels of vitamin D are associated with osteoporotic fractures, the link is not causative, according to the results of an analysis published online April 7 in Clinical Chemistry.

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IBD Symptoms in Pregnancy Tied to Higher C-Section Rate, IUGR

WEDNESDAY, April 22, 2020 (HealthDay News) -- Women with inflammatory bowel disease (IBD) have lower pregnancy rates, and those with uncontrolled disease are at increased risk for adverse outcomes, according to a study published online April 7 in Alimentary Pharmacology and Therapeutics.

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COVID-19 Tied to Unique Nasal Symptoms

TUESDAY, April 21, 2020 (HealthDay News) -- COVID-19 is not associated with the symptoms typically associated with a viral cold or allergies, such as nasal blockage or mucus production, according to a review published online April 10 in Laryngoscope Investigative Otolaryngology.

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Mental Health Consequences of COVID-19 Pandemic Explored

TUESDAY, April 21, 2020 (HealthDay News) -- A new position paper, published online April 15 in The Lancet Psychiatry, highlights the mental health consequences of COVID-19 management.

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FDA Authorizes COVID-19 Test That Uses Samples Collected at Home

TUESDAY, April 21, 2020 (HealthDay News) -- The U.S. Food and Drug Administration has approved emergency use of the first COVID-19 test that enables patients to take samples at home.

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LA County COVID-19 Infections Far Exceed Number of Confirmed Cases

TUESDAY, April 21, 2020 (HealthDay News) -- An early analysis of antibody testing from Los Angeles County reveals a COVID-19 infection rate that is up to 55 times the number of confirmed COVID-19 cases.

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Expanding Symptom Screening Criteria Can Up COVID-19 Detection

TUESDAY, April 21, 2020 (HealthDay News) -- Expanding COVID-19 symptom screening criteria to include myalgias and chills could identify more health care personnel (HCP) with the illness, according to a research letter published online April 17 in the Journal of the American Medical Association.

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Most Older Adults With New Dementia Die Within Five Years

TUESDAY, April 21, 2020 (HealthDay News) -- Most community-dwelling older adults with newly identified dementia die or are admitted to a long-term care home within five years, according to a study published online April 20 in CMAJ, the journal of the Canadian Medical Association.

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Heightened Surveillance IDs More Thyroid Cancer in 9/11 Responders

TUESDAY, April 21, 2020 (HealthDay News) -- Excess asymptomatic thyroid cancer in Fire Department World Trade Center (WTC)-exposed rescue/recovery workers is apparently attributable to the identification of occult lesions during medical surveillance, according to a study published online April 20 in JAMA Internal Medicine.

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Physicians Report Low Interest in Opioid Use Disorder Meds

TUESDAY, April 21, 2020 (HealthDay News) -- Few primary care physicians report interest in treating patients with opioid use disorder (OUD), according to a research letter published online April 21 in the Annals of Internal Medicine.

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Coinfection With SARS-CoV-2, Other Respiratory Pathogens ID'd

TUESDAY, April 21, 2020 (HealthDay News) -- About 20 percent of specimens positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are positive for other respiratory pathogens, according to a research letter published online April 15 in the Journal of the American Medical Association.

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Cardiac Cath Lab STEMI Activations Drop During Pandemic

TUESDAY, April 21, 2020 (HealthDay News) -- During the COVID-19 pandemic, there has been a 38 percent reduction in U.S. cardiac catheterization laboratory ST-segment elevation myocardial infarction (STEMI) activations, according to a research letter published online April 10 in the Journal of the American College of Cariology.

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Bundled Rapid HIV/Hep C Testing May Improve Infection Awareness

TUESDAY, April 21, 2020 (HealthDay News) -- For people with substance use disorders, combining HIV and hepatitis C virus (HCV) testing and providing immediate test results may increase the number of people who are aware of their infection status, according to a study published in the May issue of Medical Care.

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Cervical Cancer Screening Rates May Be Impacted by Disasters

MONDAY, April 20, 2020 (HealthDay News) -- Cervical cancer screening rates (CCS-Rs) in Japan were significantly lower in the years following the devastating Great East Japan Earthquake of 2011, according to a study recently published online in PLOS ONE.

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Reduced Power Plant Emissions Tied to Better Asthma Measures

MONDAY, April 20, 2020 (HealthDay News) -- Retirement of coal-fired power plants or installation of stricter emissions controls is associated with better asthma-related outcomes, according to a study published online April 13 in Nature Energy.

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Lab Protocol Failures Led to Ineffective COVID-19 Tests From CDC

MONDAY, April 20, 2020 (HealthDay News) -- The first COVID-19 tests in the United States were ineffectiv


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