Generally unknown. However, it may be caused by a genetically determined disorder of collagen tissue leading to myxomatous degeneration of the mitral valve leaflets.
Usually asymptomatic discovered by chance. Mainly affects young females and may present with chest pain (not related to effort and not relieved by nitrates) or with palpitations.
Rare complications include infective endocarditis, arrhythmias, progressive mitrial regurge, cerebral emboli, sudden death.
Assurance and follow up to detect mitrial regurgitation. Prophylaxis by antibiotics against infective endocarditis especially during dental manipulations. treatment of complications.