Create Account | Sign In: Author or Forum

Search Symptoms

Category: Gastroenterology

Back to Medical Reference

Diffuse esophageal spasm overview

Published: January 13, 2016. Updated: January 13, 2016

Diffuse esophageal spasm (DES), also known as nutcracker esophagus, is an abnormality of the neural processes in the esophagus leading to intense contractions (spasms).

Clinical picture

Patients present with intermittent chest pain (due to spasm) that is not associated with exertion and bears no relation to food. There is intermittent esophageal dysphagia to both solids and fluids that does not progress.

Barium studies show corkscrew esophagus during the time of an attack. Manometric studies show a pattern of disorganized contractions.


Treatment is with calcium channel blockers or nitrates.

Previous: Hypercholesterolemia Next: Zenker diverticulum

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?

Submit the word you see below: