Brand Name: Duricef
Pregnancy Category B
Mechanism of action of Duricef
Bactericidal: inhibits synthesis of bacterial cell wall, causing cell death.
Indications of Duricef
- UTIs caused by E. coli, P. mirabilis, Klebsiella
- Pharyngitis, tonsillitis caused by group A ?hemolytic streptococci
- Dermatologic infections caused by staphylococci, streptococci
Contraindications of Duricef
- Allergy to cephalosporins or penicillins
- Renal failure
Adverse effectsof Duricef
- CNS: Headache, dizziness, lethargy, paresthesias
- GI: Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, pseudomembranous colitis, liver toxicity
- Hematologic: Bone marrow depression
- GU: Nephrotoxicity
- Hypersensitivity: Ranging from rash, fever to anaphylaxis; serum sickness reaction
- Other: Superinfections
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