Pregnancy Category B
Mechanism of action
Bactericidal: inhibits synthesis of bacterial cell wall, causing cell death.
- Pharyngitis/tonsillitis caused by Streptococcus pyogenes
- Secondary bacterial infection of acute bronchitis and exacerabation of chronic bronchitis caused by S. pneumoniae, H. influenzae, M. catarrhalis
- Pneumonia caused by S. pneumoniae, H. influenzae
- Dermatologic infections caused by Staphylococcus aureus, S. pyogenes
- Urinary tract infections caused by E. coli, Staphylococcus saprophyticus
- Otitis media caused by S. pneumoniae, H. influenzae, M. catarrhalis, S. pyogenes
- Allergy to cephalosporins or penicillins
- Renal failure
- CNS: Headache, dizziness, lethargy, paresthesias
- GI: Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, pseudomembranous colitis, liver toxicity
- Hematologic: Bone marrow depression
- GU: Nephrotoxicity
- Hypersensitivity: Ranging from rash to fever to anaphylaxis, serum sickness reaction
- Local: Pain, abscess at injection site; phlebitis, inflammation at IV site
- Other: Superinfections
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