Back to Macrolides
Clarithromycin hydrochloride
Biaxin Filmtabs
Pregnancy Category C
Drug classes
Mechanism of action
Inhibits protein synthesis in susceptible bacteria, causing cell
death.
Indications
- Treatment of upper respiratory infections caused by S. pyogenes, S. pneumoniae
- Treatment of lower respiratory infections caused by Mycoplasma pneumoniae, S. pneumoniae, H. influenzae, M. catarrhalis
- Treatment of skin and structure infections caused by S. aureus, S. pyogenes
Contraindications
- Contraindicated in the presences of hypersensitivity to clarithromycin, erythromycin, or any macrolide antibiotic.
Use caution in the presence of colitis, hepatic or renal impairment, pregnancy, lactation.
Adverse effects
- CNS: Dizziness, headache, vertigo, somnolence, fatigue
- GI: Diarrhea, abdominal pain, nausea, dyspepsia, flatulence, vomiting, melena, pseudomembranous colitis
- Other: Superinfections
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