Back to Infections Drug Index

Back to Penicillins

Amoxicillin

Amoxil, Polymox, Trimox,
Wymox

Pregnancy Category B

Drug classes

Antibiotics
Penicillins

Mechanism of action
Bactericidal: inhibits synthesis of cell wall of sensitive organisms, causing cell death.

Indications

  1. Infections due to susceptible strains of Haemophilus influenzae, E. coli, Proteus mirabilis, Neisseria gonorrhoeae, Streptococcus pneumoniae, streptococci, nonpencillinase-producing staphylococci 

Unlabeld use: Chlamydia trachomatis in pregnancy

Contraindications

  1. Contraindicated in the presence of allergies to penicillins,
    cephalosporins, or other allergens.

Use caution in the presence of renal disorders, lactation.

Adverse effects 

  • CNS: Lethargy, hallucinations, seizures
  • GI: Glossitis, stomatitis, gastritis, sore mouth, furry tongue, black "hairy" tongue, nausea, vomiting, diarrhea, abdominal pain, bloody diarrhea, enterocolitis, pseudomembranous colitis, nonspecific hepatitis
  • Hematologic: Anemia, thrombocytopenia, leukopenia, neutropenia, prolonged bleeding time
    GU: Nephritis
  • Hypersensitivity reactions: Rash, fever, wheezing, anaphylaxis
  • Other: Superinfections-oral and rectal moniliasis, vaginitis

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us