Pregnancy Category C
- Antiviral drug
Antiviral activity against herpes simplex types 1 and 2; mechanism of action has not been established; probably interferes with DNA synthesis.
Herpes simplex virus encephalitis (parenteral administration)
Neonatal herpes simplex virus infections (parenteral administration)
Herpes simplex virus keratitis (ophthalmic administration)
Reduction of complications of herpes zoster in immunocompromised patients
Contraindicated in the presence of allergy to vidarabine, pregnancy, lactation.
Use caution in the presence of liver disease, psychoses, CHF, renal disease, CNS infections.
- CNS: Tremor, headache, psychoses, malaise, dizziness, confusion, irritability, ataxia
- GI: Nausea, vomiting, anorexia, diarrhea
- Hematologic: Decreased reticulocyte count, hemoglobin, hematocrit, WBC, platelet count, increased SGOT, total bilirubin
- Dermatologic: Pruritus, rash
- Local: Pain at injection site
- Other: Weight loss
- Local: Blurring of vision, burning or stinging on administration, photophobia
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