Doctors Lounge - Infections AnswersBack to Infections Answers List
If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge (www.doctorslounge.com) does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.
DISCLAIMER: The information provided on www.doctorslounge.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.
Date of last update: 10/12/2017.
Forum Name: AIDS
|trey3025 - Fri Jan 09, 2009 10:00 am||
I'm currently taking a 30-day supply of Truvada as a post exposure prophylactic after a high-risk exposure to HIV. I've read that even in cases where PEPs don't inhibit the transmission of HIV that they can greatly reduce the viral load during the acute phase. If this is the case, would the fact that I'm taking Truvada increase the likelihood that the HIV antibody test at the 3-week post-exposure mark would return a false negative? In other words, would a newly infected person taking Truvada produce detectable amounts of antibodies at a later date than someone who was infected but wasn't taking Truvada? I'm wondering if I should assign much credit to the results of the 3-week antibody test.
|John Kenyon, CNA - Sun Feb 08, 2009 11:02 pm||
While I am unaware of any studies which specificlaly address your question, it does stand to reason that antibodies would become reduced as the viral load is reduced (assuming the virus is even present), so it does become somewhat of a puzzle. Since HIV takes a good six weeks to develop significant antibodies anyway, the early test is essentially a baseline test, so not too much can be taken away from it unless one has already been infected for some time.
The follow up test should be far more telling, so long as the PEP has been discontinued for a few weeks before testing. It's a difficult and anxiety-producing situation at best. Hopefully your follow up test will be negative, and that will be a far more reliable exam.
Good luck to you. Please update us as things unfold.
|| Check a doctor's response to similar questions|
Are you a Doctor, Pharmacist, PA or a Nurse?
Join the Doctors Lounge online medical community
Editorial activities: Publish, peer review, edit online articles.
Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.