Name: Cyclobenzaprine hydrochloride
Pregnancy Category B
Centrally acting skeletal muscle relaxant
Precise mechanism of action not known; does not directly relax tense skeletal muscles but appears to act mainly at brain stem levels or in the spinal cord.
Relief of discomfort associated with acute, painful musculoskeletal conditions, as an adjunct to rest, physical therapy
Unlabeled use: adjunct in the management of fibrositis syndrome
Contraindicated in the presence of hypersensistivity to cyclobenzaprine, acute recovery phase of myocardial infarction, arrhythmias, heart block or conduction disturbances, CHF, hyperthyroidism.
Use with caution in the presence of urinary retention, angle-closure glaucoma, increased intraocular pressure, lactation.
- CNS: Drowsiness, dizziness, fatigue, tiredness, asthenia, blurred vision, headache, nervousness, confusion
- GI: Dry mouth, nausea, constipation, dyspepsia, unpleasant taste, liver toxicity in preclinical studies
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