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Date of last update: 10/04/2017.

Forum Name: Headaches

Question: success rate of GHE45 4 day tx for intractable migraine

 luvcthateba - Sat Sep 20, 2008 9:50 am

what is the success rate for DHE 45v for 4 day 4x day, with depakote 500 mg bid, baaclofen, and visteril q6h, with xanax in hopsital via picc line for intractable migraine?

 John Kenyon, CNA - Sun Nov 02, 2008 11:51 pm

User avatar Hello Erin -

While I've been unable to find any refernece material which quotes even an approximate success rate for the treatment you're asking after, I do know there is significant enthusiasm for it in cases of intractable migraine and cluster headaches, so long as the protocol isn't interrupted because of a reaction to any of the medications involved. I've seen the "short version" of this done in the ER, and have also found that the occasional patient admitted for the multiple-day combined course of treatment seems to come away from it greatly improved and sometimes with lasting improvement, although migraine does recur with these patients.

This is the most I can tell you: that it seems to have been well worth the aggravation in the few cases with which I've had some direct exposure, and that the doctors involved seemed quite enthused about the prospects for not only breaking the status migraine but also for overall long-term improvement of the problem. Perhaps someone else here at The Lounge is more familiar with the protocol and how successful it is in a larger population of patients.

I hope this is helpful. Best of luck to you.

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