Back to table of contents

Sunday June 16, 2002 10:25 PM GMT

free%20radicals.gif (200x200 -- 0 bytes)


Active oxygen species have long been known to be mutagenic, hence playing a role in cancer formation.


prntfrnd.gif (30x26 -- 1309 bytes)printer friendly version

Free Radicals; Types & Dangers
Antioxidants, classification and chemistry


Measuring oxidative DNA damage:

Quantitatively, the 8-hydroxylated derivative of dG is one of the most prevalent oxidised product of DNA generated in vitro under physiological conditions. This lesion also functions as a sensitive biomarker of oxidative DNA damage in vivo (Aruoma et al. 1989). This has been proved in studies using ionising radiation on human cell cultures, whole animals or bacteria. Further, the excretion of 8-hydroxy-G is correlated with age, metabolic rate, caloric intake, and antioxidant intake of diet.

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us