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Hodgkin's lymphoma

Hodgkin's disease is a type of lymphoma described by Thomas Hodgkin in 1832, and characterized by the presence of Reed-Sternberg cells.


The estimated new cases and deaths from Hodgkin's lymphoma in the United States in 2005 are:

  • New cases: 7,350

  • Deaths: 1,410

Due to the advances of therapy for Hodgkin's lymphoma over the past 4 decades more than 75% of all newly diagnosed patients can expect a disease-free normal life span.


It is slightly more common in males with a male-to-female ratio of Hodgkin?s disease is 1.3 to 1.


Unlike other lymphomas, whose incidence increases with age, Hodgkin's lymphoma has a bimodal incidence curve: that is, it occurs more frequently in two separate age groups, the first being young adulthood (age 15-35), the second being in those over 50 years old.

Race and ethnicity

Hodgkin?s disease occurs less commonly in African-Americans (2.3 cases per 100,000 persons) than in Caucasians (3.0 per 100,000 persons).


The age-specific incidence of Hodgkin?s disease differs markedly in different countries. In Japan, the overall incidence is low and the early peak is absent. In some developing countries, there is a downward shift of the first peak into childhood.

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