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Date of last update: 10/21/2017.

Forum Name: Lymphoma

Question: Question concerning stemcell transplant:

 jypsy_rose_lee - Thu May 04, 2006 10:14 pm

Which is a more servere type of transplant an Allogeneic or an Autologous transplant? Is your chances of dieing from an infection greater when using a doner's stemcells? Thanks for the information. Mary
 Theresa Jones, RN - Fri May 05, 2006 5:42 am

User avatar Hi jypsy_rose_lee,
The essential difference between Autologous bone marrow transplantation and Allogeneic bone marrow transplantation is Autologous involves hematopoietic stem cells from your own body which may be treated to remove any lingering cancer cells, and frozen for storage until after the chemotherapy/radiation treatments are complete and then returned to the body. Allogeneic transplant are healthy cells from a suitably matched donor that are introduced into the body after chemotherapy/radiation treatments are completed. As a general rule autologous transplant may be associated with fewer serious side effects than an allogenic transplant because the cells come from your own body. The physician makes the determination of which type of transplant to use based on many factors, ie, age, overall health, availability of a suitable donor, and cancer type. However, it's important to keep in mind that in some cases an autologous transplant may be less effective than an allogeneic transplant in treating certain kinds of cancer and again is based on the determination of the physician and above factors. I hope this has been somewhat helpful. Best wishes.
Theresa Jones, RN
 jypsy_rose_lee - Sat May 06, 2006 9:37 pm

Thank you Theresa,your information has been very helpful.

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