Cancer Chemotherapy Regimen for Osteosarcoma Cancer
VML osteosarcoma(109) _________________________________________________________________ vincristine..... 2.0 mg/sqm (maximum sungle dose 2.0 mg) IV on day 1. methotrexate.... 3,000 to 7,500 mg/sqm IV over 6 h beginning 30 minutes after vincristine. leucovorin...... 15 mg IV every 3 h times 8, then 15 mg orally every 6 h times 8, beginning 3 h after methotrexate infusion is completed. FREQUENCY....... Repeat cycle every 21 days. reference... Jaffe N. Frei E 3d. Watts H. Traggis D. High-dose methotrexate in osteogenic sarcoma: a 5-year experience. Cancer Treatment Reports. 62(2):259-64, 1978 Feb. abstract...
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Dr. Tamer Fouad, M.D.
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