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Date of last update: 9/5/2017.

Forum Name: Pharmacy & Drug Topics

Question: Vicodin, harmful if used with..?

 Panasonic234 - Wed Nov 14, 2007 10:47 am

My friend is a 22 year old male currently taking a Vicodin pill once a day for pain. I'm concerned if it can be harmful to him if mixed with alcohol or other drugs. Any help is greatly appreciated.

Thank you
 Debbie Miller, RN - Wed Nov 14, 2007 11:35 am

User avatar You are right to be concerned about your friend. Vicodin is a potent pain killer and serious side effects such as excessive sedation, confusion, or coma may result if alcohol is taken with it. In addition, patients who drink more than 3 alcoholic drinks a day along with this medication risk serious liver damage. Adding tobacco to this equation further increases liver risk. It logically follows that other drugs that affect the central nervous system could also aggravate side effects and cause decreased reaction time, etc. Machinery (like cars) should not be operated while taking these drugs.

Thank you for being concerned. I hope you can influence your friend. Good luck.
 Panasonic234 - Fri Nov 16, 2007 5:54 pm

Would amoxicillin follow the same rules? About how long after he stops each pill(amoxicillin,Vicodin), is it safe to take other drugs and alcohol?

 John Kenyon, CNA - Sun Jul 20, 2008 4:17 pm

User avatar Hello -

Just following up to answer your last question. Amoxicillin is an antibiotic and carries no specific contraindication to concomitant use of alcohol. As for other drugs, there are far too many to cover here, but there are some specific groups which can be cited as definitely risky when used in conjunction with alcohol, and others which should be combined only with extreme caution and the knowlege and supervision of a doctor. All opiates and opioid drugs (such as Vicodin [dehydro-oxycodone] ) should not be used in conjunction with alcohol for the reasons pointed out by Ms. Miller previously. Also, any drugs which have the potential for sedative side effect. including certain antihistimines, all actual sedatives, anti-anxiety drugs, and many antidepressants. It is always best to check with the prescribing providor if alcolhol use is possible or routine for the patient.

Hope this is helpful.

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