Doctors Lounge - Pharmacy Answers

"The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician."

Back to Pharmacy Answers List

Forum Name: Pharmacy & Drug Topics

Question: combining meds

 Anonymous - Wed Apr 16, 2003 12:09 pm

I need to know about possible problems with mixing Alegra, a high blood pressure medication, and a anti-depressant. This person I'm asking for is sleeping constantly, and also i think shes drinking regularlt with the meds as well.
please help !
 Dr. A. Rajput - Wed Apr 16, 2003 5:20 pm

User avatar as far as i know Allegra is used in allergic rhinitis...but one of the content of allergra is pseudoephidrine !! Co-administration of pseudoephedrine and MAOI’s(anti depressants) may lead to hypertensive crisis. An early warning symptom may be a throbbing headache. the danger of this interaction persists for two weeks after MAOI therapy is discontinued. Pseudoepedrine may cause hypertension and arrhythmia in patients taking tricyclic antidepressants and may antagonise the effects of hypertensive therapy which interferes with sympathetic activity (i.e. alpha and beta blockers).

| Check a doctor's response to similar questions

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us