Medical Specialty >> Pharmacy

Doctors Lounge - Pharmacy Answers

Back to Pharmacy Answers List

If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge ( does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.

DISCLAIMER: The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.

Date of last update: 9/5/2017.

Forum Name: Pharmacy & Drug Topics

Question: Apo-Amitriptyline HCl & Ecstasy

 314 - Wed Nov 05, 2008 6:35 pm

Are there any complications if these two drugs are taken together?
The Amitriptyline is for migraines, therefore only one 25mg dose is taken daily (prevents most headaches, but no other side effects)
Thank you!
 Dr. Safaa Mahmoud - Sun Nov 09, 2008 10:46 am

User avatar Hello,
To my knowledge there are no reported interactions between these two specific medications, but theoretical interaction is still possible.

The amphetamine derivative MDMA or Ecstasy is well known with its immediate short-term undesired side effects, moreover there are major concerns about its long term physical and psychological effects in the medical communities. Thus its clinical use has been discouraged long time ago and the recent available data is from its abuse and its fatal outcomes.

Some of the versions of this drug Ecstasy contains chemical compounds that may also add to the side effects.
The Food and Drug Administration (FDA) has warned consumers not to purchase a herbal version of the illegal street drug "Ecstasy" in 2004 and you can read the details in the following link:

So, informing your physician about your current medications is essential to avoid complications.

I would advise you to follow up with your doctor and to discuss with him your concerns.
Please keep us updated.
Best regards.

| Check a doctor's response to similar questions

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us