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Date of last update: 9/5/2017.

Forum Name: Pharmacy & Drug Topics

Question: migraines and prednisone

 teacher1 - Wed Jan 28, 2009 8:12 pm

I've had migraines since 1972. I have had fewer since beginning Imitrex 15 years ago. But I have to take Imitrex daily. I also have degenerative cervical discs and arthritis in my neck. I began a pack of Methylprednisolone tabs, 4mgs, 4 days ago for a prolonged cough. The headaches have been under control with much less Imitrex. Why would this medication greatly affect the headaches? And is there anything that might help the headaches like the Prednisone that I could take prophylactically?
 Tom Plamondon PA-C - Mon Feb 09, 2009 12:12 pm

User avatar Hello,

Thanks for writing in.

Prophylatic medicine for migraines are (pick one):
- nortriptyline or amitryptyline
- verapamil or diltaizem
- propanolol
- prednisone

Each medicine has it's own benefit and side effect profile so considering other medical diagnosis and your other medications is important.

Consult your family physician for the best prophylactic medicine for you.

Also, for migraines it is important to avoid triggers (specific foods eg caffeine and chocolate and some medicines eg hormone replacement drugs and some SSRI's).

Take care and keep us posted.

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