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Date of last update: 9/5/2017.

Forum Name: Pharmacy & Drug Topics

Question: Lethargy with Omeprazole - is this normal?

 PauliePorsche - Sun Jul 25, 2010 6:00 pm

This drug treats my GERD wonderfully, but I've noticed I'm markedly more lethargic and simply don't have the energy levels i once did. Yes, I can pin it to this drug (the one time I discontinued my energy levels shot back up again).

Is there anything I can do to help alleviate this? Does this go away over time? Supplements of some sort?
 Faye Lang, RN, MSW - Wed Jul 28, 2010 9:51 pm

Hello, PauliePorsche,

You've asked some difficult questions. Lethargy has been reported by some patients taking Omeprazole, and some small studies have been conducted, but it doesn't appear that any long-term controlled studies have been done. Side effects of any drug may resolve over time as the person's individual metabolism and chemistry adjusts to the drug, but this is not always the case. The most appropriate action would be to discuss the situation with your doctor. A regular, mild and progressive exercise program may help improve and restore energy levels, if approved by your doctor. Biotin is known to improve energy, but should not be added without your doctor's knowledge and approval, and an alternate medication might be his or her preferred choice. I encourage you to see your doctor at your earliest convenience to discuss your concerns.

I hope this information is helpful to you. Good luck!

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