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Forum Name: Antidepressants
Question: Effexor and weight gain
|pain in the sunshine stat - Wed Dec 14, 2005 1:39 pm||
I have been on Effexor XR for over a year I am taking 225 mg, my diet has not changed and I am active. I do not have a routine excercise plan, but I never had one either. I have blown up in my belly midsection. Can Wellbutrin by perscribed with Effexor XR?
|Dr. Tamer Fouad - Thu Dec 15, 2005 1:12 am||
Venlafaxine (Effexor), a potent inhibitor of serotonin and norepinephrine reuptake, is sometimes prescribed for patients with psychomotor retardation, hypersomnia, or resistance to other antidepressants. A short-term study comparing venlafaxine (Effexor) with fluoxetine (Prozac) found no significant weight gain with either agent. Thus, like SSRIs and unlike mirtazapine, venlafaxine (Effexor) is less likely to cause weight gain in the short term, although there are not enough data to comment on its long-term effects.
You will need to discuss the possibility of changing your medication with your psychiatrist.
1. Stahl SM. Psychopharmacology of antidepressants. London, UK: Dunitz 1998.
2. Silverstone PH, Ravindran A. Once daily venlafaxine extended release compared with fluoxetine in outpatients with depression and anxiety. Venlafaxine XR 360 Study Group. J Clin Psychiatry 1999; 60:22–28.
3. Guelfi JD, Ansseau M, Timmerman L, Korsgaard S. Mirtazapine vs venlafaxine in hospitalized severely depressed patients with melancholic features. Mirtazapine-Venlafaxine Study Group. J Clin Psychopharmacol 2001; 21:425–431.
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