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Date of last update: 8/24/2017.

Forum Name: Antidepressants

Question: Being switched to Celexa

 tjford - Sun Sep 05, 2004 6:39 pm

After being on Effexor XR for 6 months with very little effect, my doctor has finally agreed to switch my medication. Until four days ago, I had been taking 150 mg of Effexor XR (split dose - 75 mg. am; 75 mg pm). For the past four days, my dose has been reduced by my doctor to 75 mg. (which I take in the morning) I am to stay at 75 mg. for another 3 days and then start Celexa. Over the past few days I have found that when I take my 75 mg. in the morning I am very nauseaus. I actually feel better in the morning before I take the Effexor. Could this be because I had been taking a split dose or that my body metabolizes the drug quickly? Also, could starting the Celexa upon discontinuation of the Effexor XR help ease the potential withdrawal symptoms?

 Carolyn Merritt, LPN - Wed Oct 13, 2004 2:53 pm

User avatar The side effects experienced with these drugs disappear upon discontinuation of the drug. There are currently no ominous long term problems with this class of drugs. However, they have only been around 15 years or so, so just starting to see European patients with long term histories. The withdrawal syndrome is best described as "flu like". Headaches, muscle aches, nausea etc. this can last 1-2 weeks. About 30% of patients have a withdrawal syndrome.

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