Medical Specialty >> Psychiatry

Doctors Lounge - Psychiatry Answers

Back to Psychiatry Answers List

If you think you may have a medical emergency, call your doctor or 911 immediately. Doctors Lounge (www.doctorslounge.com) does not recommend or endorse any specific tests, physicians, products, procedures, opinions, or other information that may be mentioned on the Site.

DISCLAIMER: The information provided on www.doctorslounge.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Please read our 'Terms and Conditions of Use' carefully before using this site.

Date of last update: 8/24/2017.

Forum Name: Antidepressants

Question: ZOLOFT INCREASE


 Mason4477 - Thu Mar 27, 2008 1:39 pm

Hello. I was diagnosed with Panic Disorder and put on Zoloft. For the last month I was taking 50 mg with no side effects except dry mouth and dry eyes for the first couple of days. My doctor raised it two days ago to 100 mg. Last night I got very lightheaded and almost passed out. Began shaking, really fast heartbeat, cold chills and sweat, diarrhea, and my body felt heavy all over I could barely walk because my legs were stiff. I ate a yogurt and felt a little better within 30 minutes and fell asleep. I feel a little better today, but I still feel a little shaky on the inside. Is this normal??
 Dr. E. Seigle - Wed Apr 02, 2008 8:07 pm

Dear Mason4477,

You are likely having a not uncommon adverse reaction to the increased dose of Zoloft. What you experienced yesterday sounds like potentially serious adverse reactions to the Zoloft, as well as common, less serious side effects to Zoloft and similar medications. It is encouaging that you are somewhat better today. An immediate reduction in your dose of Zoloft is likely appropriate, and I would discuss this right away with your prescribing physician. He or she may want you to take a day off from the Zoloft tomorrow and then restart it the next day at 75 mg per day, or simply reduce to 75 mg per day tomorrow. Again, talk to your physician tomorrow before taking any Zoloft. If stiffness, shivering, or fever comes back, it is a potential emergency (possibly representing an adverse reaction known as the serotonin syndrome) and you should call your doctor immediately or go to the emergency room. Good luck!

-Eliot Seigle MD

| Check a doctor's response to similar questions

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us