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Date of last update: 8/24/2017.

Forum Name: Antidepressants

Question: Safe to take Parnate 2 weeks after Prozac?

 eufsma - Fri Dec 19, 2008 2:55 pm

I took Prozac for two days in a row, 40 mg each day.

It's been 2 weeks since those 2 days of Prozac.

Can I take an MAOI, or do I have to wait the full 5 weeks?
 Dr. E. Seigle - Thu Feb 12, 2009 8:34 pm

Hi eufsma,

The safest answer is yes, you should wait the full five weeks. However, if you under the close supervision of a psychiatrist, she might consider allowing you to start the Parnate sooner, with the proviso that you have the proper education regarding the possibility of a hypertensive crisis, so that you could seek medical attention. In addition, patients often are given to hold and take in case they experience the headache of a hypertensive crisis, special medications that can block this from occuring. Sometimes, chlorpromazine is used, in a single dose, and there are others for blocking the hypertensive reaction. Even so, it would be important to do this only under careful supervision and with a visit to an emergency room or your physician immediately should it occur.

-E. Seigle MD

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