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Date of last update: 8/24/2017.

Forum Name: Psychiatric Topics

Question: Spironolactone and Extreme depression

 Hoople - Thu May 07, 2009 11:35 am

I recently went coldturkey off 200mg Spiro. I immediately fell into a bad depression so went back on it. Currently weaning off. What would it be about spiro that induced the depression? (I suffer from depression anyway). THankyou
 Debbie Miller, RN - Thu May 21, 2009 10:56 pm

User avatar Hello,
Hormone altering medications could conceivably affect your mood but I suspect it has more to do with underlying and untreated depression itself than the medication withdrawal. You should seek help for your depression to make sure you are getting adequate treatment. This can take a little while so don't expect immediate results. If you think it helps to wean gradually off the spironolactone, that's fine, assuming it isn't causing you other problems (potassium levels can be increased).

Depression is serious and you should get the help you need for it, regardless of the other medications.

Best wishes.

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